Ethyl 5 Carbamoyl 6 Oxo 4 Phenyl 2 Trifluoromethyl 1 4 5 6 Tetrahydro Pyridine 3 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1,4,5,6-tetrahydro-pyridine-3-carboxylate

    Specifications

    HS Code

    740358

    Chemical Formula C17H15F3N2O4
    Molecular Weight 368.31
    Physical State Solid (predicted)
    Appearance White to off - white powder (predicted)
    Melting Point No data available (but can be determined experimentally)
    Boiling Point No data available (but can be estimated based on related compounds)
    Solubility Solubility in common organic solvents like DMSO, DMF; low solubility in water (predicted)
    Pka No data available (but can be estimated for acidic or basic groups in the molecule)
    Logp Estimated logP value indicating lipophilicity (no exact value given, but relative lipophilic due to phenyl and trifluoromethyl groups)
    Density No experimental density data available (but can be calculated or determined experimentally)

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    Frequently Asked Questions

    As a leading Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1,4,5,6-tetrahydro-pyridine-3-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate?
    Ethyl - 5 - carbamoyl - 6 - oxo - 4 - phenyl - 2 - trifluoromethyl - 1,4,5,6 - tetrahydro - pyridine - 3 - carboxylate is an organic compound. Its chemical properties are rich and unique.
    From the structural point of view, this compound contains an ester group (ethoxycarbonyl group), and the ester group is active. It can be hydrolyzed under hydrolysis conditions, when catalyzed by acids or bases. Hydrolyzed in an acidic medium, the corresponding carboxylic acids and alcohols will be gradually formed; in an alkaline environment, carboxylic salts and alcohols will be formed.
    Furthermore, there are carbonyl groups in the molecule, including the carbonyl group of 6-oxo and the carbonyl group of carbamoyl. Carbonyl is electrophilic and vulnerable to attack by nucleophiles. In case of nucleophiles containing active hydrogen, such as alcohols and amines, nucleophilic addition reactions can occur. Take the reaction with alcohols as an example, acetals or semi-acetals can be formed; react with amines, or form amide products.
    In addition, the aromatic ring (phenyl group) in the molecule gives it a certain stability and conjugation effect. Aromatic rings can participate in electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Due to the distribution of electron cloud density, electrophilic reagents are prone to attack specific positions of aromatic rings and form corresponding substitution products.
    The trifluoromethyl group in the molecule has a strong electron-absorbing effect due to the extremely high electronegativity of fluorine atoms. This not only affects the distribution of molecular electron clouds, but also changes its physical and chemical properties, such as improving the lipid solubility of compounds, and can affect the reactivity and selectivity in chemical reactions. The reaction check point of trifluoromethyl ortho-site or para-site, the electron cloud density decreases, and the electrophilic substitution reactivity may change; and the reaction on the carbon atom connected to it may make the carbon atom more vulnerable to nucleophilic reagents due to the electron-absorbing induction effect.
    This compound has a variety of functional groups that interact with each other, making its chemical properties complex and diverse, and may have important applications in the fields of organic synthesis and medicinal chemistry.
    What are the main uses of Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate?
    Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate, is an organic compound. Its main use is often involved in the field of organic synthesis.
    In the process of organic synthesis, this compound can be used as a key intermediate. Due to its unique structure, many functional groups contained in the cover, such as carboxyl ester group, aminoformyl group, carbonyl group, etc., are highly reactive. From this, chemists can use a variety of chemical reactions, such as esterification, amidation, nucleophilic addition, etc., to derive many compounds with complex structures and specific functions.
    For example, amide compounds with novel biological activities can be constructed by amidation with specific amines. Such compounds may emerge in the field of drug research and development, providing the possibility for the search for new pharmaceutical active ingredients. Furthermore, its ester groups can be hydrolyzed or participate in transesterification reactions under suitable conditions, thereby constructing carboxylic acid derivatives or esters with different structures, which are widely used in materials science, fragrance chemistry and other fields.
    In materials science, modified-derived compounds may endow materials with unique physical and chemical properties, such as improving their solubility, thermal stability, or even endowing them with special optical and electrical properties. In the field of fragrance chemistry, the newly generated esters may present a unique aroma, which adds to the preparation of fragrances.
    And because it contains trifluoromethyl, this functional group endows the compound with special physical, chemical and biological activities, such as enhancing the lipophilic and stability of the compound, and then affecting its biological activity and metabolic properties. Therefore, ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate is an important intermediate in the field of organic synthesis, which has contributed greatly to the progress of drug development, materials science, fragrance chemistry and many other disciplines.
    What is the synthesis method of Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate?
    To prepare Ethyl - 5 - carbamoyl - 6 - oxo - 4 - phenyl - 2 - trifluoromethyl - 1,4,5,6 - tetrahydro - pyridine - 3 - carboxylate, the following ancient method can be used.
    First take a suitable starting material, which is based on a compound containing phenyl, trifluoromethyl and other corresponding structures. In a suitable reaction vessel, according to the ancient formula, place the starting material in it. First introduce a specific reagent under mild conditions to initiate a preliminary reaction. This step aims to build the basic carbon skeleton and some functional groups. The reagents used must be pure and free of impurities, and the measurement must be accurate to ensure a smooth reaction.
    Then, gradually adjust the temperature, pressure and other conditions in the reaction system to gradually deepen the reaction. When heating up, it is necessary to carefully observe the reaction situation to prevent overheating from causing side reactions. When the reaction reaches a specific stage, add reagents that can form carbamoyl groups and ester groups, carefully regulate the reaction process, so that each functional group is formed in sequence, and accurately construct the structure of the target product.
    During the reaction process, the ancient monitoring methods are often used, such as observing the color change of the reaction solution and the presence or absence of precipitation, etc., to roughly judge the progress of the reaction. When the reaction is nearly complete, according to the ancient method of post-treatment, first extract with a suitable solvent to separate the organic phase and the aqueous phase, and remove impurities. After distillation, recrystallization and other methods, the product is purified to obtain the pure product of Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1,4,5,6-tetrahydro-pyridine-3-carboxylate. In this process, each step needs to be strictly operated and followed the rules of the ancient regulations to obtain satisfactory results.
    Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate What are the precautions during storage and transportation?
    Ethyl - 5 - carbamoyl - 6 - oxo - 4 - phenyl - 2 - trifluoromethyl - 1,4,5,6 - tetrahydro - pyridine - 3 - carboxylate is an organic compound. Many matters need to be paid attention to during storage and transportation.
    When storing, the first environment is drying. This compound is susceptible to water vapor. If the environment is humid, or chemical reactions such as hydrolysis can damage its purity and quality. It should be placed in a desiccant or in a storage place to keep the environment dry.
    Temperature is also critical. Store in a cool place to avoid high temperature. High temperature may cause the compound to decompose, or accelerate its chemical reaction rate and reduce stability. Generally speaking, the storage temperature should not exceed 25 ° C.
    Avoidance from light is also indispensable. Light or luminescent chemical reactions affect the properties of the compound. Can be stored in brown bottles, or placed in storage cabinets protected from light.
    During transportation, the packaging must be stable. This compound may have certain sensitivity, transportation vibration or collision or cause package damage, and then leakage. Suitable packaging materials, such as strong glass bottles, should be selected, and filled with cotton, foam and other cushioning materials to prevent it from shaking and colliding.
    Furthermore, environmental conditions during transportation should also be controlled. Keep the transportation environment dry, cool, and avoid extreme temperature and humidity.
    In addition, relevant regulations and safety standards should be strictly followed for the storage and transportation of this compound. Operators need to be professionally trained and familiar with operating norms and emergency treatment methods to ensure that the entire process is safe and safe from harm to personnel and the environment.
    What is the market outlook for Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate?
    Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate is an organic compound. However, in the current market prospect, it needs to be carefully examined from multiple perspectives.
    From the perspective of the pharmaceutical field, this compound may have potential medicinal properties. Its unique chemical structure may lay the foundation for the development of new drugs. Today, the pharmaceutical industry is hungry for innovative drugs, and many pharmaceutical companies and research institutes are making every effort to explore novel active ingredients. If this compound is studied in depth, it can show significant pharmacological activities, such as anti-tumor, anti-inflammatory, anti-cardiovascular diseases, etc., and has minimal toxic and side effects, it will surely attract widespread attention. At that time, it may attract a lot of investment for follow-up clinical trials and drug development. Once it is successfully approved for listing, its market prospect will be extremely broad, or it can bring huge profits to enterprises.
    In the field of materials science, this compound may be able to make a name for itself in the preparation of special materials. It contains special functional groups, or endows the material with unique properties, such as improving the stability, optical properties or electrical properties of the material. With the continuous advancement of science and technology, the demand for high-performance materials is increasing. If this compound can be applied to high-end electronic materials, optical materials and other fields to meet the urgent demand for advanced materials in the market, it can also open up a considerable market.
    However, the market expansion of this compound also faces many challenges. The first one is the complexity of the synthesis process. If the synthesis steps are cumbersome and costly, it will greatly limit its large-scale production and application. Furthermore, safety and environmental friendliness cannot be ignored. In today's era of environmental protection and safety, compounds need to pass strict relevant tests before they can enter the market.
    In summary, although Ethyl-5-carbamoyl-6-oxo-4-phenyl-2-trifluoromethyl-1, 4, 5, 6-tetrahydro-pyridine-3-carboxylate have addressable market opportunities, they need to overcome many difficulties in order to gain a firm foothold in the market and shine.