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What is the chemical structure pyridine-3-carboxylate Ethyl 5-AMinoopyrazolo [1,5-a]?
Ethyl + 5 - AMinoopyrazolo%5B1%2C5 - a% 5Dpyridine - 3 - carboxylate, this is the English name of organic compounds. According to chemical naming rules and structural analysis methods, its corresponding chemical structure is: with pyrazolo [1,5 - a] pyridine as the parent nucleus, there is a formate group at the 3rd position of the pyridine ring, and an amino group at the 5th position of the pyrazole ring.
According to this name, "Ethyl" Epiethyl, is a common organic group, such as -C ² H. "5 - AMino", which appears to have an amino group (-NH2O) at a specific position (5th position). " Pyrazolo [1,5-a] pyridine "Pyrazolo [1,5-a] pyridine, a heterocyclic structure formed by fusing a pyridine ring with a pyrazole ring. And" 3-carboxylate "indicates that there is a carboxyl-derived ester group attached to the 3 position of the pyridine part of the heterocyclic ring, which is named ethyl formate (-COOCH ² CH).
In this way, the chemical structure of Ethyl + 5 - AMinoopyrazolo%5B1%2C5 - a% 5Dpyridine - 3 - carboxylate is clarified.
What are the common synthesis methods of Ethyl 5-AMinoopyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl 5 - AMinoopyrazolo [1,5 - a] pyridine - 3 - carboxylate (5 - aminopyrazolo [1,5 - a] pyridine - 3 - carboxylate ethyl ester) common synthesis methods are as follows:
The starting material can be selected as a compound containing pyridine and pyrazole structures, and it can be reacted in multiple steps to form this target product. The first method is to introduce the pyridine ring structure at a specific location using a suitable pyridine derivative as a raw material. This process requires the condensation reaction of the pyridine derivative with the pyridine precursor containing the pyrazole structure under a suitable base and solvent environment. In the reaction, the base can promote the formation of the nucleophilic test agent, and the solvent needs to ensure the solubility of the reactants and the stability of the reaction system.
Method 2 uses pyrazole derivatives as the starting materials to construct pyridine rings through a series of reactions. For example, in the presence of a catalyst, pyrazole derivatives are cyclized with specific nitrogenous and carboxyl-containing reagents to form the basic skeleton of the target product. This cyclization reaction requires strict reaction conditions. Temperature, catalyst dosage and reactant ratio all have a great impact on the reaction process and yield.
There is another method 3, which is achieved by multi-step functional group conversion with easily available simple raw materials. First, the intermediates containing amino groups, carboxyl groups and potential pyrazole and pyridine structure fragments are prepared, and then the complete 5-amino pyrazolo [1,5-a] pyridine-3-carboxylic acid ethyl ester structure is gradually constructed through intramolecular cyclization, modification and other reactions. Each step of the reaction requires fine regulation of the reaction conditions to ensure the selectivity and high efficiency of functional group conversion.
The above synthetic methods have their own advantages and disadvantages. In practical application, the best method should be selected according to factors such as raw material availability, cost and reaction conditions.
What are the physical properties of Ethyl 5-AMinoopyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl 5-AMinoopyrazolo [1,5-a] pyridine-3-carboxylate is an organic compound, which can be called 5-aminopyrazolo [1,5-a] pyridine-3-carboxylate in Chinese. Its physical properties are as follows:
The appearance is mostly white to light yellow crystalline powder, which is easy to observe and handle. In many chemical reactions and preparations, this appearance is conducive to judging its purity and reaction process.
The melting point is in a specific range, usually between 100-110 ° C. As an important physical property, the melting point can not only be used to identify the compound, but also is of great significance for the study of its stability and phase changes at different temperatures. Knowing the melting point allows chemists to precisely control the reaction temperature to ensure the smooth progress of the reaction.
In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents such as ethanol and dichloromethane. This solubility characteristic determines its application scenarios in different solvent systems. In organic synthesis, selecting a suitable solvent to dissolve the compound can effectively promote the contact between reaction molecules and improve the reaction efficiency.
In addition, the compound has certain stability, but when exposed to strong oxidants, strong acids or strong bases, chemical reactions may occur and structural changes may occur. Store in a cool, dry and well-ventilated place away from the above substances to maintain the stability of its chemical structure and physical properties.
What are the applications of Ethyl 5-AMinoopyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl 5 - Aminoopyrazolo [1,5 - a] pyridine - 3 - carboxylate is an organic compound that has applications in many fields.
In the field of pharmaceutical research and development, such compounds with nitrogen-containing heterocyclic structures often exhibit unique biological activities. Due to their structural properties, they can interact with specific targets in organisms, or they can be used as lead compounds. After structural modification and optimization, new drugs, such as anti-cancer drugs, are expected to inhibit the growth and spread of cancer cells by precisely acting on specific proteins or signaling pathways of cancer cells; or anti-inflammatory drugs, by modulating inflammation-related signaling molecules, reduce inflammatory responses.
In the field of materials science, they may be involved in the synthesis of functional materials. For example, it can be used as a building unit to prepare materials with special optical and electrical properties. With the electronic properties of nitrogen atoms in its molecular structure, it can be used to make organic Light Emitting Diode (OLED) materials, giving the material unique luminous properties and improving the display effect; or it can be used to prepare conductive polymer materials, providing the possibility for the miniaturization and flexibility of electronic devices.
In the field of agricultural chemistry, or can be used to create new pesticides. Use its impact on specific biological activities to develop high-efficiency, low-toxicity and environmentally friendly insecticides and fungicides. It can precisely act on the specific physiological processes of pests or pathogens, interfering with their normal growth and reproduction, thereby ensuring the healthy growth of crops and improving agricultural production efficiency.
In summary, Ethyl 5 - Aminoopyrazolo [1,5 - a] pyridine - 3 - carboxylate has important application potential in the fields of medicine, materials, agriculture, etc. With the deepening of research, more novel and practical uses may be discovered.
What is the market outlook for Ethyl 5-A Minoopyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl 5-Aminoopyrazolo [1,5-a] pyridine-3-carboxylate is an organic compound, or 5-aminopyrazolo [1,5-a] pyridine-3-carboxylate in Chinese. Looking at its market prospects today, it covers the following ends.
From the field of pharmaceutical research and development, such nitrogen-containing heterocyclic compounds often have unique biological activities. In recent years, pharmaceutical research has demanded novel active molecules, and their structural properties may make them potential drug intermediates. For example, drug design targeting specific disease targets may provide novel ideas and structural templates for developers, and it is expected to emerge in the future creation of anti-malarial, anti-cancer and other drugs. Therefore, its prospects in the pharmaceutical raw material market are promising.
In the field of pesticides, nitrogen-containing heterocyclic compounds are also a research and development hotspot. With the development of green and efficient pesticides, such compounds may have good insecticidal and bactericidal activities due to their unique chemical structures, and are relatively friendly to the environment. If their active mechanisms can be deeply excavated in research and development, and the structure can be optimized, there should be a wide range of fields in the field of new pesticide creation, which can be favored by the market.
However, its market prospects are not without challenges. The complexity of the synthesis process affects its large-scale production and cost control. If the synthesis route is long and the conditions are harsh, the cost will be difficult to drop, which will be unfavorable to market competition. Furthermore, market awareness also needs to be improved. Although its structure has potential advantages, it needs close cooperation between scientific research and marketing activities to make more companies and developers aware of its potential in order to expand market share.
Overall, Ethyl 5 - Aminoopyrazolo [1,5 - a] pyridine - 3 - carboxylate has great potential in the field of pharmaceutical and pesticide research and development. If it can overcome the synthesis problem and improve market awareness, its market prospect will be quite bright.