ethyl 4-methylpyrazolo[1,5-a]pyridine-3-carboxylate

ethyl+4-methylpyrazolo%5B1%2C5-a%5Dpyridine-3-carboxylate is 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate ethyl ester, which has a wide range of uses.
In the field of medicine, it is often used as a key intermediate. Pyrazolopyridine compounds have diverse biological activities, such as anti-tumor, anti-inflammatory, antibacterial, etc. By modifying and modifying the structure of 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate ethyl ester, many new drugs can be created. For example, when developing anti-tumor drugs, scientists use this as a starting material to introduce specific active groups through multi-step reactions to construct molecular structures that fit the target of tumor cells to inhibit the growth and proliferation of tumor cells.
In the field of pesticides, it also has important value. Pyrazolopyridine derivatives show good insecticidal and bactericidal activities. 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate ethyl ester can be used as a lead compound, and new pesticides with high efficiency, low toxicity and environmental friendliness can be developed through structural optimization. For example, in the creation of new insecticides, compounds designed and synthesized based on their structures can specifically act on the nervous system or physiological metabolic pathways of pests, effectively kill pests, and have little impact on non-target organisms.
In the field of organic synthesis, 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate ethyl ester is an important synthetic building block. With its unique structure and activity, it participates in the construction of many complex organic molecules. Through reactions such as nucleophilic substitution and addition with different reagents, various functional groups can be introduced to expand the diversity of molecular structures and provide a key material basis for the development of organic synthetic chemistry.

This is the synthesis method of Ruyan ethyl 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate. The synthesis of this compound often involves a multi-step reaction.
The first step is often to use suitable pyridine derivatives as the starting material. Or introduce a specific substituent before the pyridine ring, which can be achieved by nucleophilic substitution, electrophilic substitution and other reactions. For example, using halogenated pyridine as the substrate, with active methylating reagents, in the presence of suitable bases and solvents, nucleophilic substitution is performed to introduce methyl groups, which is the basis for constructing the specific structure of the target molecule.
The second step is to construct the dense ring structure of pyrazolo [1,5-a] pyridine. Or use a nitrogen-containing heterocyclic construction strategy to react with specific functional groups in pyridine derivatives with compounds containing hydrazine or hydrazone groups. It is often necessary to control the reaction conditions, such as temperature, reaction time and the proportion of reactants, to promote the reaction to proceed in the direction of the formation of the target fused ring structure. In the reaction, the catalysis of acid or base may be required to promote the cyclization reaction.
In the final step, ethyl ester group is introduced. Or the intermediate with carboxyl group is esterified with ethanol under the catalysis of acid to achieve the synthesis of the target product ethyl 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate. After the reaction, it is often necessary to go through separation and purification steps, such as column chromatography, recrystallization, etc., to obtain high-purity products.
The fine regulation of the reaction conditions in each step is crucial for the synthesis of this compound, so that satisfactory yield and purity can be obtained.

Ethyl 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate, that is, ethyl 4-methylpyrazolo [1,5-a] pyridine-3-carboxylate, is an organic compound. Its physical and chemical properties are as follows:
In terms of view, it is often in the state of a crystalline solid. As for the color, or colorless, or white, when the quality is pure, it is mostly this appearance. This is due to the regular molecular structure and the orderly crystal form.
In terms of melting point, it is in a specific temperature range. This characteristic is due to the synergy between molecular forces and crystal structure. There are van der Waals forces and hydrogen bonds between molecules to maintain crystal stability. When heated to a certain extent, this force is destroyed, resulting in the performance of melting point.
The boiling point also has its value. At a certain temperature range, if the substance is to change from liquid to gaseous state, it needs to be supplied with energy to overcome the attractive force between molecules. Molecular mass, type of intermolecular force and strength all affect the boiling point.
Solubility is very important. It has certain solubility in organic solvents such as ethanol, chloroform, dichloromethane, etc. Because the compound molecule contains polar groups and non-polar parts, it can be miscible with organic solvents through the principle of similar compatibility. Polar groups interact with the polar part of the organic solvent, and the non-polar part is compatible with the non-polar part. However, in water, the solubility is not good. Due to the relatively strong hydrophobicity of the overall structure, it is difficult to form effective interactions between water molecules and compound molecules.
In terms of stability, it is relatively stable under normal conditions. In case of strong acid, strong base or high temperature, strong oxidant and other special conditions, the molecular structure may change. In case of strong acid, some atoms or groups in the molecule or protonation, resulting in structural and property changes; in case of strong base, or triggering hydrolysis reaction, causing ester group fracture, forming corresponding acids and alcohols.
The physical and chemical properties of this compound are crucial for its application in organic synthesis, medicinal chemistry and other fields. Only by knowing its properties can it be reasonably used for reactions and the development of new compounds or drugs.

I don't know what the market price of ethyl 4 - methylpyrazolo [1,5 - a] pyridine - 3 - carboxylate is. "Tiangong Kaiwu" is an ancient book describing the skills of hundreds of workers. It was formed in the Ming Dynasty, when chemical synthesis was not as developed as it is today. Such fine organic compounds have not yet been prepared, and there is no book on the price of this compound.
Today is different from the past, and the price of this compound is affected by many factors. First, the difficulty of preparation affects the price. If the synthesis steps are complicated, special reagents are required, and harsh reaction conditions are required, the cost will be high and the price will be expensive. Second, the amount of market demand is related to the price. If there is strong demand for it in many fields and the supply is in short supply, the price will be high; conversely, the demand is few and the price may be low. Third, the purity determines the price. High-purity products are often used in high-end scientific research, medicine and other fields, and the preparation is difficult, and the price is much higher than that of low-purity products.
To know the exact price of this product, you can consult chemical product suppliers, or find it on professional chemical product trading platforms. Each supplier may have different quotations due to different cost and profit considerations. Therefore, multi-party comparison can obtain more accurate price information.

Ethyl-4-methylpyrazolo [1,5-a] pyridine-3-carboxylic acid esters are used in various fields such as medicine, pesticides and materials science.
In the field of medicine, it is a key intermediate for the synthesis of many biologically active compounds. Due to the unique structure of pyrazolopyridine, it can be closely combined with various targets in organisms, so this compound can be carefully designed and modified, or new and efficient drugs can be created. For example, in the development of anti-tumor drugs, derivatives constructed on this basis are expected to act precisely on specific targets of tumor cells, interfere with malignant biological behaviors such as tumor cell proliferation and invasion, and provide a new way to overcome cancer problems. In the treatment of neurological diseases, innovative drugs that can regulate neurotransmitters and repair nerve damage may also be developed by leveraging their structural advantages.
In the field of pesticides, ethyl-4-methylpyrazolo [1,5-a] pyridine-3-carboxylate can be used as a starting material for the development of new pesticides. Due to its unique chemical structure, the derived pesticides may have excellent insecticidal and bactericidal activities. For example, for specific crop pests, the prepared pesticides can specifically interfere with the nervous system or physiological and metabolic processes of pests, kill pests efficiently, and are environmentally friendly, with low residues, which is in line with the needs of the current development of green agriculture. At the same time, in terms of sterilization, it may inhibit the growth of a variety of plant pathogens, protect crops from disease attacks, and ensure food yield and quality. < Br >
In the field of materials science, it can be applied to the synthesis of organic optoelectronic materials. Because of its structure with specific electronic properties, it may endow materials with unique optical and electrical properties. For example, in organic Light Emitting Diode (OLED) materials, the introduction of this structure may improve the material's luminous efficiency, stability and other properties, and promote the further development of display technology. In the field of solar cell materials, it may optimize the material's ability to absorb light and transport charge, improve the photoelectric conversion efficiency of solar cells, and contribute to the development of renewable energy.