Ethyl 4-amino-6-chloro-pyridine-3-carboxylate

Ethyl 4-amino-6-chloro-pyridine-3-carboxylate is 4-amino-6-chloropyridine-3-carboxylate ethyl ester. This compound contains a pyridine ring, which is a six-membered nitrogen-containing heterocycle and has aromatic properties. Its 3-position is connected to a carboxylic acid ethyl ester group (-COOCH ² CH 😉). In this group, the carbonyl group (C = O) has a strong polarity and is conjugated with the oxygen atom in the ester group, which affects the properties of the compound. The 4-position linked amino group (-NH ²), the amino group is basic and nucleophilic, and can participate in a variety of reactions. The 6-position chlorine atom (-Cl) has a large electronegativity and can undergo substitution reactions. In the overall structure, each group affects each other, so that the compound exhibits unique physicochemical properties and reactivity. As the core structure, the pyridine ring imparts aromatic stability to the compound, while the different positions of the substituents expand its reaction possibilities and application directions, and may have important uses in organic synthesis, pharmaceutical chemistry and other fields.

Ethyl 4-amino-6-chloro-pyridine-3-carboxylate (ethyl 4-amino-6-chloropyridine-3-carboxylate) is widely used in the field of organic synthesis.
First, it is often used as a key intermediate to prepare various compounds containing pyridine structures. Pyridine rings are important structural units in many drugs, pesticides and material molecules. With this compound, other functional groups can be introduced through substitution, condensation and other reactions to obtain products with specific activities. For example, when creating new antibacterial drugs, modifying the substituents on the pyridine ring of the intermediate may enhance the inhibitory effect of the drug on specific bacteria.
Second, in the field of pesticide synthesis, it also plays an important role. It can be converted into pesticide components with insecticidal, bactericidal or herbicidal activities through a series of reactions. Because its pyridine structure can endow molecules with suitable lipophilic and hydrophilic balance, which helps them better act on target organisms, it may be possible to develop efficient and low-toxic pesticide varieties.
Furthermore, in the field of materials science, this is used as a starting material, or materials with special optoelectronic properties can be synthesized. The conjugate structure of the pyridine ring may have a significant impact on the electrical and optical properties of the material. After rational molecular design and reaction, functional materials can be prepared for organic Light Emitting Diode (OLED), solar cells and other devices, contributing to the development of the materials field.
In summary, Ethyl 4-amino-6-chloro-pyridine-3-carboxylate has shown potential and important application value in many fields such as drugs, pesticides and materials due to its unique structure, and is an indispensable substance for the development of organic synthetic chemistry research and related industries.

Ethyl 4 - amino - 6 - chloro - pyridine - 3 - carboxylate is an important compound in the field of organic synthesis. Its synthesis methods are common in the following kinds.
First, the compound containing the pyridine ring is used as the starting material. Appropriate pyridine derivatives can be found first, and they can be substituted at specific positions under specific conditions. For example, a pyridine compound is reacted with a chlorine-containing reagent in a reactor with a suitable catalyst, suitable temperature and pressure, and the chlorine atom is introduced at the 6th position of the pyridine ring. Then, through a cleverly designed reaction path, the amino group is introduced at the 4th position, and the carboxyl group is introduced at the 3rd position, and it is converted into the ethyl ester form. This process requires fine regulation of the reaction conditions of each step, such as reaction temperature, reactant ratio, reaction time, etc. A slight difference in pooling may lead to low yield or by-products.
Second, you can also start with the construction of pyridine rings. With the help of multi-step organic reactions, the pyridine ring skeleton is first synthesized, and during the construction process, the required amino groups, chlorine atoms and carboxylethyl ester groups are introduced synchronously or step by step. For example, using some common organic raw materials, through condensation, cyclization and other reactions, the pyridine ring structure is gradually built. In the cyclization reaction, the reactants and reaction conditions are carefully selected, so that each substituent on the pyridine ring is connected at a predetermined position. Subsequently, the formed pyridine ring product is modified and transformed to achieve the synthesis of Ethyl 4-amino-6-chloro-pyridine-3-carboxylate. Although this method is complicated, it requires extremely high precision in controlling each step of the reaction. If it can be properly operated, a high purity target product can be obtained.
Third, a synthesis strategy catalyzed by transition metals can also be used. Transition metal catalysts are often highly effective in promoting specific organic reactions. In the synthesis of this compound, transition metals can be used to catalyze the coupling reaction between specific substrates, and small molecules containing amino groups, chlorine atoms and carboxyl ethyl esters can be precisely linked through coupling reactions to construct target molecules. This method relies on the selection of transition metal catalysts and the optimization of the reaction system. It is necessary to consider the activity and selectivity of the catalyst, as well as the influence of reaction solvents, ligands and other factors on the reaction, and strive to achieve efficient and highly selective synthesis.

Ethyl 4 - amino - 6 - chloro - pyridine - 3 - carboxylate is an organic compound with unique physical properties. It is mostly solid at room temperature, and its appearance is white to light yellow crystalline powder. This morphological feature is easy to identify and operate.
Looking at its melting point, it is about a specific temperature range, which is of great significance in identification and purity determination. Due to the different purity of the compound, the melting point may vary. In terms of boiling point, there is also a corresponding value, which reflects the temperature at which it changes from liquid to gas under a specific pressure, which is crucial for separation and purification operations.
In terms of solubility, the substance exhibits different behaviors in organic solvents. In common organic solvents such as ethanol and acetone, it may have a certain solubility, while in water, the solubility is relatively limited. This difference in solubility provides a basis for its separation, purification and reaction medium selection.
Density is a certain value, reflecting its mass per unit volume, and is indispensable for accurate measurement and behavior research in a specific system. In addition, the compound may have a specific odor. Although the odor description or your mileage may vary, it is also part of its physical properties, which can be used as a preliminary basis for judgment during actual contact and operation. These physical properties are interrelated and together constitute the physical properties of the compound, laying the foundation for its application in chemical, pharmaceutical and other fields.

At this time, I want to know the price of Ethyl 4 - amino - 6 - chloro - pyridine - 3 - carboxylate in the market, but I don't know the details. Looking at ancient books such as "Tiangong Kaiwu", although there are all kinds of products, it is difficult to find the price of this chemical product, or it was not produced at that time.
In today's world, the price of a chemical often varies according to the purity of the quality, the amount of production, and the urgency of the request. If the quality is abundant and the number of seekers is small, the price is cheap; if the quality is excellent but rare, and the number of seekers is high, the price will be high.
If you want to know the price of this product, you should consult the chemical material supplier, or visit it on the chemical trading platform. Merchants there often learn about the change in its price and can tell the recent price. Or refer to the prices of the same kind and push the approximate price. However, prices are volatile, rising and falling, and must eventually be stopped in real time.