Ethyl 4 5 6 7 Tetrahydro 1h Pyrrolo 3 2 C Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

ethyl 4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate

    Specifications

    HS Code

    341899

    Chemical Formula C10H14N2O2
    Molar Mass 194.23 g/mol
    Appearance Typically a solid (but appearance can vary based on purity and synthesis method)
    Physical State At Room Temperature Solid
    Solubility In Water Low solubility, relatively hydrophobic
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Melting Point Data may vary by source, but generally in a certain range specific to its crystalline form
    Odor Odorless or faint odor
    Pka pKa values of relevant acidic or basic groups can be measured, data specific to its functional groups

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    General Information
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    Frequently Asked Questions

    As a leading ethyl 4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of ethyl 4,5,6, 7-tetrahydro-1H-pyrrolo [3,2-c] pyridine-2-carboxylate?
    This is the chemical structure analysis of ethyl 4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid ester. Looking at its name, its structural elements can be analyzed step by step. "Ethyl" refers to an alkyl group containing two carbon atoms, expressed as -C ² H, as one of the ester groups. "4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine", this is a fused heterocyclic system. "pyrrolido" means formed by fusing pyrrole rings with pyridine rings. "[ 3,2-C] "shows the positional relationship between the fused two rings." 4,5,6,7-tetrahydro "indicates that the number of hydrogen atoms changes at the 4th, 5th, 6th, and 7th positions of the fused ring system, that is, the four primary double bonds are hydrogenated to form a single bond." 2-carboxylate "indicates that a carboxylic acid ester group is connected at the 2nd position of the fused ring, and the previous" ethyl group "is combined, which can be known as the -COOCH -2 CH 🥰 structure. In summary, the chemical structure of ethyl 4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid ester is an organic compound with a specific fused heterocycle as the core, an ethyl carboxylic acid ester group attached at the 2 position, and the fused ring at the 4, 5, 6, and 7 positions is in the hydrogenated state.
    What are the main uses of ethyl 4, 5, 6, 7-tetrahydro-1H-pyrrolo [3,2-c] pyridine-2-carboxylate
    Ethyl 4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid ester, which is widely used. In the field of medicinal chemistry, it is often used as a key intermediate to help create a variety of specific drugs. Due to its unique chemical structure, it can be cleverly derivatized to build a variety of bioactive molecules, such as innovative drugs targeting specific disease targets. In the field of organic synthesis, this compound can participate in rich organic reactions such as nucleophilic substitution, electrophilic substitution, cycloaddition, etc., providing key building blocks for the synthesis of complex organic molecules, helping chemists to create organic materials with novel structures and unique properties, which are applied in the field of materials science. In addition, in the process of drug development, it can also serve as a lead compound optimization template. Chemists can modify its structure to enhance drug activity and improve pharmacokinetic properties, thereby promoting the development of new drugs. In conclusion, ethyl 4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid esters are of great value and wide use in many scientific fields.
    What are the synthesis methods of ethyl 4,5,6, 7-tetrahydro-1H-pyrrolo [3,2-c] pyridine-2-carboxylate
    There are several methods for the synthesis of ethyl 4, 5, 6, 7 - tetrahydro - 1H - pyrrolo [3, 2 - c] pyridine - 2 - carboxylate.
    One of the methods can be initiated by suitable pyridine derivatives. First, the pyridine is used as a base, and an appropriate substituent is introduced at a specific position to construct the pyrrolido-pyridine skeleton through a multi-step reaction. For example, the pyridine ring is first electrophilic substitution reaction, so that a suitable functional group is attached at a specific position, and then the cyclization reaction is carried out to form a pyrrolido-pyridine structure. On the basis of this structure, the carboxyl group is converted into ethyl ester group through esterification reaction, so as to obtain the target product ethyl 4,5,6,7-tetrahydro-1H-pyrrolo [3,2-c] pyridine-2-carboxylate. In this process, the electrophilic substitution reaction needs to select suitable reagents and conditions to ensure the selectivity and yield of the reaction. The cyclization reaction also needs fine regulation, such as temperature, catalyst and other factors, so that the reaction can proceed in the desired direction.
    The second method can also be a compound containing pyrrole structure as the starting material. First, the pyrrole ring is modified, and the pyridine-related fragments are introduced. After a series of reactions, a complete pyrrole-pyridine system is constructed. Then, as in the previous method, the esterification operation is carried out to generate the target ethyl ester product. In this path, the modification reaction of the pyrrole ring is quite critical, and the activity and selectivity of the pyrrole ring need to be considered. The subsequent reaction of constructing pyridine fragments also requires careful selection of reagents and conditions to achieve the ideal synthesis effect.
    Or it can start from simple hydrocarbons and nitrogen-containing and oxygen-containing small molecules, and gradually synthesize in multiple steps to construct pyridine rings, pyrrole rings, and then esterification. Although this approach has many steps, it can be effectively obtained if the reaction conditions of each step are precisely controlled. In short, there are various methods for synthesizing ethyl 4, 5, 6, 7 - tetrahydro - 1H - pyrrolo [3, 2 - c] pyridine - 2 - carboxylate, and each method has its advantages and disadvantages. It is necessary to choose the appropriate one according to the actual situation, such as the availability of raw materials, the ease of control of reaction conditions, and the purity requirements of the product.
    What are the physical properties of ethyl 4,5,6, 7-tetrahydro-1H-pyrrolo [3,2-c] pyridine-2-carboxylate
    Ethyl-4,5,6,7-tetrahydro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid ester, an organic compound. Its physical properties are particularly important, related to its application and characteristics.
    Looking at its properties, under normal temperature and pressure, it is mostly colorless to light yellow liquid, with a clear and fluid appearance. The color and morphology of this substance are extremely critical in visual identification and operation. If its color is different or morphological changes are seen, it may indicate that its purity has changed or chemically changed.
    When it comes to boiling point, it can reach a certain temperature range under specific pressure conditions. The value of this boiling point affects the method of separation and purification. When covering operations such as distillation, the temperature needs to be controlled according to its boiling point to achieve the purpose of separating pure substances. The boiling point also reflects the strength of intermolecular forces, which is related to its stability and volatility.
    In terms of melting point, if the compound is in a solid state, it also has a corresponding melting point. Determination of melting point is an important means to identify its purity and characteristics. The melting point of pure substances is fixed. If it contains impurities, the melting point will often drop and the melting range will increase.
    Solubility is also an important physical property. In common organic solvents, such as ethanol, dichloromethane, etc., it may have certain solubility. This property is crucial in organic synthesis reactions, and is related to the smooth progress of the reaction and the separation and purification of the product. Choosing a suitable solvent can promote the mixing of the reactants, increase the reaction rate, and also facilitate the precipitation of the products from the reaction system.
    Density is the mass per unit volume. Knowing its density is indispensable when measuring and calculating the proportion of the reactant. Substances of different densities also vary in stratification during mixing, which has a great impact on some liquid-liquid reactions or separation operations.
    The physical properties of this compound are of critical significance in many fields such as organic synthesis and medicinal chemistry, laying the foundation for related research and applications.
    Ethyl 4,5,6, 7-tetrahydro-1H-pyrrolo [3,2-c] What is the market outlook for pyridine-2-carboxylate
    Wen Jun inquired about the market prospects of ethyl 4, 5, 6, 7 - tetrahydro - 1H - pyrrolo [3, 2 - c] pyridine - 2 - carboxylate, and I will describe it in quaint words.
    This compound is gradually showing its unique value in the current field of chemistry and medicine. Looking at the road of pharmaceutical research and development, the search for many innovative drugs often relies on various characteristic compounds as the cornerstone. Ethyl 4, 5, 6, 7 - tetrahydro - 1H - pyrrolo [3, 2 - c] pyridine - 2 - carboxylate seems to have potential biological activity due to its special molecular structure, which can be relied on by pharmaceutical chemists to create novel therapeutic agents.
    In the corner of materials science, there may be a place for it to be used. Today's material research and development strives for excellent performance and unique functions. If this compound is cleverly modified and integrated, it may endow the material with different characteristics, such as improving its stability, conductivity or optical properties, thus opening up new fields of material application.
    However, although its market prospects are promising, there are still thorns. The complexity of the synthesis process is the primary challenge. If we want to produce it on a large scale to meet the needs of the market, we must optimize the synthesis method, reduce costs and increase yield. And market competition should not be ignored. Similar or alternative compounds may have entered the market first and occupy a place. In order to stand out in this market, it is necessary to highlight its unique advantages, whether it is excellent performance or low cost.
    Furthermore, changes in regulations and policies also affect its market trend. The pharmaceutical and materials industries are strictly regulated. If this compound is used in related products, it must meet various regulatory requirements, which is also a factor that cannot be ignored.
    Overall, ethyl 4,5,6,7 - tetrahydro - 1H - pyrrolo [3,2 - c] pyridine - 2 - carboxylate Although the prospect is promising, the way forward requires careful planning, breaking through technical bottlenecks, gaining insight into market trends, and conforming to the trend of regulations, in order to achieve good results in the market.