Ethyl 3 Pyridine 2 Ylamino Propanoate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 3-(pyridine-2-ylamino)propanoate

    Specifications

    HS Code

    394477

    Chemical Formula C11H14N2O2
    Molar Mass 206.24 g/mol
    Appearance Solid (usually)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, chloroform
    Melting Point Typically in a certain range (data may vary depending on purity)
    Boiling Point Specific boiling point under standard conditions (data may vary)
    Odor May have a characteristic odor
    Density Specific density value (data may vary)
    Ph Neutral in pure form (in aqueous solution, may have a pH close to 7 depending on hydrolysis)

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    General Information
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    Frequently Asked Questions

    As a leading Ethyl 3-(pyridine-2-ylamino)propanoate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of Ethyl 3- (pyridine-2-ylamino) propanoate?
    Ethyl 3- (pyridine-2-ylamino) propanoate is an organic compound. Its molecule contains a structure of pyridine ring connected to ethoxycarbonyl, which gives it unique chemical properties.
    From the perspective of physical properties, this compound is often liquid or solid at room temperature and pressure, depending on its purity and crystal form. Its melting point and boiling point have specific values due to the intermolecular forces, which are derived from the hydrogen bonds and van der Waals forces in the structure. Due to the presence of polar groups in the molecule, such as amino and ester groups, it has good solubility in polar solvents, but poor solubility in non-polar solvents.
    On chemical properties, due to the presence of amino groups, it has a certain alkalinity and can react with acids to form salts. The presence of pyridine rings makes molecules aromatic and can participate in electrophilic substitution reactions, such as halogenation, nitrification, etc. The reactivity is affected by the electronic effect of the substituents on the ring. Ester groups can undergo hydrolysis reactions. Under acidic or basic conditions, the hydrolysis rate is different from that of the product. Under acidic conditions, 3- (pyridine-2-ylamino) propanoic acid and ethanol are hydrolyzed to form 3- (pyridine-2-ylamino) propanoic acid and ethanol; under basic conditions, the corresponding carboxylate and ethanol are formed. This hydrolysis reaction is a common reaction of esters. At the same time, the carbon-nitrogen bonds, carbon-oxygen bonds, etc. in the molecule can also participate in various organic reactions under appropriate conditions, such as interacting with nucleophiles or electrophiles, thus deriving a variety of organic synthesis pathways, laying the foundation for the preparation of more complex organic compounds.
    What are the main uses of Ethyl 3- (pyridine-2-ylamino) propanoate?
    Ethyl 3- (pyridine-2-ylamino) propanoate is an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its special chemical structure, it can interact with a variety of bioactive molecules to help create drugs with specific curative effects, or make a name for itself in the development of drugs for neurological diseases and cardiovascular diseases.
    In the field of materials science, this compound may participate in the synthesis of polymer materials. With its amino and carboxylethyl ethyl esters and other active groups, it can polymerize with other monomers to shape materials with unique properties, such as special solubility, mechanical properties or optical properties, providing an opportunity for the development of new materials.
    Furthermore, in the field of organic synthesis chemistry, Ethyl 3- (pyridine-2-ylamino) propanoate can be used as a cornerstone for the construction of more complex organic molecules. Due to the reactivity conferred by the pyridine ring with amino and ester groups, it can expand the molecular structure and enrich the variety of organic compounds through various organic reactions, such as nucleophilic substitution and addition reactions, providing a powerful tool for organic synthesis chemists to explore new reaction pathways and compound structures.
    What is the synthesis method of Ethyl 3- (pyridine-2-ylamino) propanoate
    Ethyl 3- (pyridine-2-ylamino) propanoate has many synthesis methods. One common one is to use 2-aminopyridine and ethyl acrylate as starting materials, and under suitable reaction conditions, the nucleophilic addition reaction of the two is performed. In this process, the amino group of 2-aminopyridine is nucleophilic, and the double bond of ethyl acrylate is electrophilic, and the two interact. During the reaction, suitable solvents, such as dichloromethane, N, N-dimethylformamide, etc., need to be selected to provide a stable environment for the reaction. And temperature control is required, generally between room temperature and moderate heating, to ensure a smooth and efficient reaction. < Br >
    There is also a synthesis method. 2-aminopyridine can be modified with appropriate functional groups first, such as introducing protective groups, to prevent unnecessary side reactions. After that, it can be condensed with compounds containing carboxyl groups or their active derivatives to obtain the target product. The choice of condensation reagents is also key, such as dicyclohexyl carbodiimide (DCC) combined with 4-dimethylaminopyridine (DMAP), which can effectively promote the reaction. After the reaction is completed, the protective group is removed to obtain Ethyl 3- (pyridine-2-ylamino) propanoate.
    Furthermore, the method of transition metal catalysis can be used. Palladium, copper and other metals are used as catalysts to couple halopyridine derivatives with compounds containing allyl esters under the synergistic action of ligands. This approach requires fine regulation of catalyst dosage, ligand types and reaction conditions to improve the selectivity and yield of the reaction.
    What should be paid attention to when storing Ethyl 3- (pyridine-2-ylamino) propanoate?
    Ethyl 3- (pyridine-2-ylamino) propanoate is an organic compound. When storing, many aspects need to be paid attention to.
    First, temperature is very important. This compound is mostly sensitive to temperature. Excessive temperature may cause it to decompose, deteriorate, or accelerate its chemical reaction rate, reducing its purity and stability. Therefore, it should be stored in a cool place. Generally speaking, the temperature should be controlled within the range of 5 to 25 degrees Celsius, which can effectively delay the change of its physical and chemical properties.
    Second, humidity cannot be ignored. Humid environment can easily make the compound absorb moisture, cause adverse reactions such as hydrolysis, and destroy its chemical structure. It needs to be stored in a dry place. It can be maintained in a dry environment with the help of desiccants, etc., and the relative humidity should be controlled at 40% to 60%.
    Third, light will affect it. Some organic compounds are prone to photochemical reactions under light, and Ethyl 3- (pyridine-2-ylamino) propanoate or the same is true. It should be stored in a dark container, such as a brown glass bottle, to reduce the effect of light on it and prevent it from failure or impurities due to reactions such as photolysis.
    Fourth, the storage place should be well ventilated. If the storage environment is poorly ventilated, the volatile gas of the compound will accumulate, which may not only endanger the health of the storage personnel, but also under certain conditions, there may be safety hazards such as explosion. Good ventilation can disperse volatile gases in time, maintain fresh air, and reduce safety risks.
    Fifth, be sure to store it separately from other chemicals. Ethyl 3- (pyridine-2-ylamino) propanoate or react with other substances, such as oxidants, acids, bases, etc. Storage separately can avoid accidental reactions and ensure its stability and safety.
    In short, when storing Ethyl 3- (pyridine-2-ylamino) propanoate, temperature, humidity, light, ventilation and isolation from other chemicals should be carefully considered to ensure the stability of the compound and reduce the risk of deterioration and safety.
    What is the market price of Ethyl 3- (pyridine-2-ylamino) propanoate?
    Nowadays, there is something called Ethyl 3- (pyridine-2-ylamino) propanoate. It is difficult to determine the price of the market. The change in its price depends on multiple ends.
    First, the supply and demand of this thing affects its price. If there are many people who ask for it, but the supply is small, the price will increase; conversely, the supply exceeds the demand, and the price may drop. If at a certain time, the karma needs a lot of money for Ethyl 3- (pyridine-2-ylamino) propanoate, but the producer does not meet it enough, and the price remains high.
    Second, the cost of production is also a major reason. The cost of raw materials, labor, equipment, etc. for producing this product is all related to the price. If the price of raw materials increases, or the cost of labor increases, the cost of making this product will increase, and its price in the market will also increase. If the production of raw materials changes, making it difficult to obtain, the price will be expensive, and the price of this product will therefore be higher.
    Third, the competition in the market has a very small impact. If there are many people who make this product, they will compete to sell it at a good price, and the price may be lower. Businesses want to compete for customers, or reduce prices to sell, hoping to get a share of the market.
    Fourth, the regulations of government orders also matter. If the tax adjustment and the rules of access can make the price different. If the tax is heavy, the cost of the business will increase, and the price will rise; if the regulation is strict, it will be difficult to increase the production, and it will also cause the price to change.
    Therefore, the price of Ethyl 3- (pyridine - 2 - ylamino) propanoate city cannot be summarized in a word. Only by looking at supply and demand, costs, competition, and decrees can we obtain its approximate price.