Ethyl 3 Aminofuro 2 3 B Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

ethyl 3-aminofuro[2,3-b]pyridine-2-carboxylate

    Specifications

    HS Code

    580340

    Chemical Formula C11H12N2O3
    Iupac Name ethyl 3 - aminofuro[2,3 - b]pyridine - 2 - carboxylate
    Appearance Solid (predicted)
    Boiling Point Predicted to be around 344.5°C at 760 mmHg
    Density Predicted density around 1.309 g/cm³
    Solubility Poorly soluble in water, likely more soluble in organic solvents like ethanol, dichloromethane
    Pka No common pKa values found (depends on functional groups and environment)
    Flash Point Predicted flash point around 162.2°C
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate
    Ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate is the name of an organic compound. To clarify its chemical structure, its naming needs to be explained in detail. "Ethyl" indicates that this compound contains ethyl, which is a simple alkyl group composed of two carbon atoms and five hydrogen atoms. The structural formula is -C ² H. "3 - amino" indicates that there is an amino group (-NH ²) substitution at the No. 3 position of the furo [2,3 - b] pyridine ring. "Furo [2,3 - b] pyridine" is the parent nuclear structure. The furo-pyridine ring is formed by fusing the furan ring with the pyridine ring, and the two rings share two carbon atoms. The furan ring is a five-membered heterocyclic ring containing one oxygen atom; the pyridine ring is a six-membered heterocyclic ring containing one nitrogen atom. "2-carboxylate" indicates that there is a carboxylate group connected at position 2, here it is an ethyl ester group (- COOCH -2 CH 😉).
    The chemical structure of this compound is the main structure of a furanopyridine fused ring, with an amino group at position 3 and an ethyl ester at position 2. The other ethyl group is connected to the whole main structure through some chemical bond. Its overall structure is complex and unique, and it may have potential uses in organic synthesis, medicinal chemistry and other fields. Due to its nitrogen, oxygen heteroatoms, amino groups, ester groups and other functional groups, caps can endow compounds with diverse chemical properties and reactivity, and can participate in various organic reactions, or serve as key intermediates for the synthesis of more complex compounds.
    What are the main uses of ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate
    Ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate is an organic compound with a wide range of main uses.
    In the field of medicinal chemistry, this compound plays a key role. It can act as an important intermediate to assist in the synthesis of drug molecules with specific biological activities. For example, due to its unique chemical structure, it may participate in the construction of drugs that act on the nervous system, interact with neurotransmitter receptors, regulate nerve signaling, and then be used to treat neurological-related diseases, such as neuropain and anxiety. Or in the development of anti-tumor drugs, it may become a starting material for the synthesis of drugs with specific molecular mechanisms that target cancer cells, promising to open up new avenues for cancer treatment.
    In the field of materials science, ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate is also useful. It can be used in the preparation of functional organic materials, such as optoelectronic materials. With its electronic structure properties, in the preparation of organic Light Emitting Diode (OLED) materials, it may improve the luminous properties of materials, improve the luminous efficiency and stability, and enable OLED screens to achieve better display effects. It may also be used to synthesize sensing materials with high sensitivity and selectivity to specific gases, and be used in the field of environmental monitoring to accurately detect specific harmful gas components in the air.
    At the level of scientific research and exploration, this compound is used as a research object to help scientists in-depth explore the mechanism of organic chemical reactions. By using it as a substrate to carry out various reactions, analyze the laws of chemical bond fracture and formation during the reaction process, provide experimental basis and data support for the development of organic synthetic chemistry theory, and promote the continuous progress of organic chemistry.
    What are the synthesis methods of ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate
    The method of synthesizing ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate is a significant exploration in the field of organic synthesis.
    First, the amino group can be introduced by amination reaction with suitable furanopyridine derivatives as starting materials. First, the starting material and the amination reagent interact under suitable reaction conditions. Pay attention to the choice of temperature and solvent in the reaction environment. If the temperature is too high, it may cause side reactions and cause poor product purity; if the temperature is too low, the reaction rate will be delayed and take a long time. The solvent needs to be able to dissolve the reactants well and be compatible with the reaction system without interfering with the reaction process.
    Second, after the amino group is introduced, the esterification reaction is carried out to form the ethyl ester structure. Select appropriate alcohol and carboxylic acid derivatives, or use corresponding esterification methods, such as acid-catalyzed esterification. In this step, the type and amount of catalyst are crucial, which can significantly affect the reaction rate and yield. If the amount of catalyst is too small, the reaction is difficult to advance efficiently; too much may cause other unnecessary side reactions.
    Furthermore, there is another way. Furanopyridine skeletons can be constructed first, and clever planning can be made during the construction process to reserve functional groups that can be converted into amino and ester groups at specific positions. Subsequently, these functional groups are sequentially transformed, and the target molecule ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate is synthesized through carefully designed reaction steps. After each reaction step, proper separation and purification operations are required to ensure the purity of the intermediate product, laying a good foundation for subsequent reactions, so that the target product can be obtained efficiently and with high purity.
    What are the physical properties of ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate
    Ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate is an organic compound. Its physical properties are crucial and relevant to many practical applications.
    This compound is mostly solid under normal conditions. Due to the strong interactions between molecules, such as hydrogen bonds and van der Waals forces, the molecules are closely arranged to form a stable lattice structure.
    In terms of melting point, the specific molecular structure and interaction cause it to have a certain melting point value. Functional groups such as amino groups and ester groups in the molecule affect the stability and melting point of the molecule by virtue of their interactions.
    In terms of solubility, according to the principle of similar miscibility, its solubility is better in organic solvents, such as common organic solvents such as ethanol and acetone. Due to the formation of similar forces between these organic solvents and the molecules of the compound, such as dipole-dipole interactions, the solubility can be improved. However, the solubility in water may be limited due to the fact that the molecular polarity does not match exactly with water, and the intermolecular forces are different from the mode of action of water molecules.
    Appearance may be white to off-white crystalline powder, which is determined by the orderly arrangement of molecules in the solid state and the characteristics of light reflection and scattering.
    Ethyl 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate has important applications in organic synthesis, drug development and other fields due to its physical properties. For example, in organic synthesis, its solid-state properties are used to facilitate separation and purification; in drug development, solubility, melting point, and other properties can affect drug dosage form design and bioavailability.
    What is the market outlook for ethyl 3-aminofuro [2,3-b] pyridine-2-carboxylate
    Today there is ethyl + 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate, and its market prospect is related to many parties. This compound has great potential in the field of pharmaceutical research and development. Due to its unique chemical structure, it may provide an opportunity for the creation of new drugs. In the exploration of innovative drugs, researchers often seek compounds with unique structures to explore their new efficacy in treating diseases.
    In the field of materials science, there are also possible applications. For example, it may be chemically modified to have special optical and electrical properties for the preparation of new functional materials. For example, some organic compounds can be cleverly designed to play a key role in optoelectronic devices.
    However, its market development also faces challenges. If the process of synthesizing the compound is complex and expensive, it will limit its large-scale production and application. To develop the market, it is necessary to optimize the synthesis method, reduce costs and increase yield.
    Furthermore, the market competition situation cannot be ignored. Compounds of the same type or with similar functions may already occupy part of the market share. To stand out, it is necessary to highlight its unique advantages, such as higher activity and better stability.
    In summary, ethyl + 3 - aminofuro [2,3 - b] pyridine - 2 - carboxylate has a promising future, but in order to gain a foothold in the market, it is still necessary to overcome problems such as synthesis cost and competition. Through unremitting research and development and innovation, it is expected to gain a broad market space.