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What is the chemical structure of ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate?
Eh, this "ethyl + 2 - oxo - 1 - phenyl - 1,2,4,5,6,7 - hexahydropyrazolo [1,5 - a] pyridine - 3 - carboxylate" has the name of the compound. If you want to know the name of the chemical, the naming method of the chemical is to solve it.
In this name, "ethyl" is also an ethyl group, which is often referred to as "ethyl", and its formula is - CH ³ CH. "Carboxylate" means that it is a carboxylic acid ester, that is, it has the element of - COO -, and this is an ethyl phase, which forms the ester part of - COOCH -2 CH.
"2 - oxo - 1 - phenyl - 1,2,4,5,6,7 - hexahydropyrazolo [1,5 - a] pyridine - 3 -" This section is the description of the core. "1,2,4,5,6,7 - hexahydropyrazolo [1,5 - a] pyridine" Table 1 is a fused system, formed by the fusing of pyrazolopyridine, and the 1, 2, 4, 5, 6, 7 positions of this system are all reduced, that is, the phase is not mixed with the pyrazolopyridine, and this system is more complex. " 2-Oxo "means that there is a one-carbonyl group (C = O) at the second position of the system, and" 1-phenyl "means that there is a phenyl group (-C H) at the first position of the system." 3 - "indicates that the carboxyl group (esterified ester group) is located at the third position of the system.
On this compound, it is 1, 2, 4, 5, 6, 7-hexapyrazolo [1,5-a] pyridine mother nucleus, 1-phenyl, 2-carbonyl, and 3-carboxylate ethyl. It can be roughly shown as follows: by means of a fused system, each of the above-mentioned bases is connected at a specific position on the system, and is arranged in the characteristic space of the compound.
What are the main physical properties of ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl-2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylic acid ester, this is an organic compound. Its main physical properties are as follows:
- ** Properties **: Usually in the state of white to off-white crystalline powder, this is its common appearance, and it is stable under normal conditions.
- ** Melting point **: The melting point of this compound is in a specific range, but it fluctuates slightly due to differences in preparation process and purity. This melting point characteristic can be used for preliminary identification and purity judgment. Melting point determination follows specific experimental methods to accurately determine its melting temperature range. < Br > - ** Solubility **: In organic solvents, such as ethanol, dichloromethane, etc., it exhibits a certain solubility. In ethanol, with the increase of temperature, the solubility increases. This property is related to the polar groups in the molecular structure. Polar groups interact with organic solvent molecules to promote the dissolution process. However, in water, the solubility is relatively low, because the overall polarity of the molecule is limited, and the interaction with water molecules is weak.
- ** Density **: The density is about [X] g/³ cm. As an inherent property of a substance, the density depends on the molecular mass and the way of molecular accumulation. Its density value is crucial for determining the dosage of substances and the ratio of reaction systems in organic synthesis and material research. < Br > - ** Stability **: It has good stability in a dry environment at room temperature and pressure. However, in case of strong acid, strong alkali, or high temperature and high humidity conditions, chemical reactions may occur and cause structural changes. Under strong light irradiation, luminescent chemical reactions may also be induced. This stability feature is of great significance for the storage and use of this compound, and it needs to be properly preserved to maintain its chemical structure and properties stability.
What are the applications of ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate?
Ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate is an organic compound that has applications in many fields.
In the field of pharmaceutical research and development, such compounds containing nitrogen heterocyclic structures often exhibit a variety of biological activities. Or have potential pharmacological activities and can be used as lead compounds for the development of new drugs. Researchers have modified its structure to explore its effect on specific disease-related targets, such as inhibition of the growth of certain tumor cells or regulation of proteins related to neurological diseases, hoping to develop new therapeutic drugs.
In the field of materials science, this compound may participate in the preparation of materials with special properties due to its unique structure. Or can be used as a functional monomer to polymerize with other substances to impart specific optical, electrical or mechanical properties to the material. For example, materials with specific fluorescence properties are prepared by polymerization reaction and used in the field of biological imaging or optical sensors.
In the field of organic synthesis, it can be used as a key intermediate. Because its structure contains multiple active check points, it can be derived through a variety of organic reactions. Through reactions such as nucleophilic substitution and electrophilic addition, more complex organic molecular structures can be constructed, providing an effective way for the synthesis of natural product analogs or new organic functional molecules. Ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate has important application value in the fields of medicine, materials and organic synthesis, and provides key material basis and research direction for the development of related fields.
What are the synthesis methods of ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate?
The method of preparing ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate has various paths.
First, it can be obtained from a suitable starting material through cyclization. First, take a nitrogen-containing and carbonyl-containing compound with a specific structure, and add an appropriate amount of catalyst to a suitable reaction medium. Common catalysts, such as acids or bases. If an acid is used as a catalyst, the nucleophilic addition and dehydration steps in the molecule can occur one after another. During this process, the raw material molecules interact and go through complex intermediates to gradually build the pyrazolopyridine ring structure of the target product. For example, a compound containing a benzene ring and an ortho-active group of the nitrogen atom and a carboxylic acid ester derivative with a carbonyl group are used as starting materials. Under mild acidic conditions, in an organic solvent such as toluene or dichloromethane, when heated and stirred for a few times, the target product can gradually form the prototype. After subsequent separation and purification steps, such as column chromatography or recrystallization, pure ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate.
Second, a multi-step reaction strategy can also be used. First, the key intermediate is prepared by conventional organic synthesis methods. For example, the pyrazole ring part is first constructed, and the hydrazine compound is reacted with the β-dicarbonyl compound to form a pyrazole derivative. The reaction conditions are relatively mild and can occur at room temperature or slightly heated in alcoholic solvents. Subsequently, the pyrazole derivatives are modified to introduce pyridine ring fragments. This can be achieved by means of nucleophilic substitution or electrophilic substitution reactions, and appropriate reagents and reaction conditions can be selected according to the properties and positions of the substituents required to be introduced on the pyridine ring. Finally, ethyl ester groups are introduced through esterification to achieve the synthesis of ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate. Although this multi-step strategy is slightly complicated, the selectivity of each step is higher, which can effectively control the purity and structure of the product.
How stable is ethyl 2-oxo-1-phenyl-1,2,4,5,6,7-hexahydropyrazolo [1,5-a] pyridine-3-carboxylate?
Eh! To know the characterization of ethyl + 2 - oxo - 1 - phenyl - 1,2,4,5,6,7 - hexahydropyrazolo [1,5 - a] pyridine - 3 - carboxylate, it is important to consider the factors of its transformation and external environment.
This compound has the characteristics of pyrazole and pyridine, and its framework should be determined. Among them, the existence of phenyl groups can disperse the sub-cloud and increase the characterization of molecules due to the co-effect of aromatics. However, there are carbonyl and other functionalities on it, and carbonyl is resistant, which can be multiplexed and reversed, or affect its characterization.
As far as the external environment is concerned, if the degree of resistance increases, the molecule may increase, which may cause it to disintegrate and crack, and the quality of the molecule may decrease. In case of acid resistance, because the compound contains reversible functional properties, it is easy to reverse, and the quality of the compound is also affected. In case of acid, carbonyl or progeny, it will lead to a series of reactions.
If it is in the oxidizing environment, some parts of the molecule may be oxidized and the original quality will be broken. On the contrary, in the inert environment, low temperature and neutral environment, the compound may be able to maintain the high quality of the phase. Therefore, ethyl + 2 - oxo - 1 - phenyl - 1, 2, 4, 5, 6, 7 - hexahydropyrazolo [1, 5 - a] pyridine - 3 - carboxylate is characterized by the interaction of external factors.