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What is the chemical structure of Ethyl 2-amino-7-isopropyl-5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate
Alas! This is a question about the structure of compounds in organic chemistry. "Ethyl + 2 - amino - 7 - isopropyl - 5 - oxo - 5H - [1] benzopyrano [2,3 - b] pyridine - 3 - carboxylate", according to organic nomenclature, "Ethyl" is ethyl, which is a genus of hydrocarbon groups. "2 - amino" indicates that there is an amino group at the 2nd position, and "7 - isopropyl" is connected to the 7th position of the isopropyl group. " 5-Oxo "shows a carbonyl group at the 5th position, and" 5H - [1] benzopyrano [2,3-b] pyridine "shows a fused heterocyclic structure, which is formed by fusing benzopyran with pyridine. This fused ring system has specific conjugation and electron distribution." 3-carboxylate "refers to a carboxylate group at the 3rd position.
In summary, the structure of this compound is based on benzopyranopyridine as the core skeleton, with amino group at the 2nd position, isopropyl group at the 7th position, carbonyl group at the 5th position, and ethyl carboxylate at the 3rd position. This structure endows the compound with unique chemical properties and potential activities, which may be of great value in organic synthesis, drug development and other fields.
What are the physical properties of Ethyl 2-amino-7-isopropyl-5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate
Ethyl 2 - amino - 7 - isopropyl - 5 - oxo - 5H - [1] benzopyrano [2,3 - b] pyridine - 3 - carboxylate is an organic compound. Its physical properties are as follows:
In terms of appearance, this compound is often in a crystalline solid state. As for the color, or white to off-white, this color indicates that its molecular structure is regular, there are few impurities, the internal arrangement is orderly, and the light is reflected and scattered evenly on its surface, so it presents such a pure color.
Melting point is one of its important physical properties. After many experiments, the melting point of the compound is within a specific range, which reflects the strength of intermolecular forces. The higher melting point means that the intermolecular forces are large, and more energy is required to disintegrate the lattice structure, and the molecules change from solid to liquid. This property is closely related to the hydrogen bonds, van der Waals forces, and conjugate systems existing in the molecule.
Solubility is also a key property. In organic solvents, such as ethanol and dichloromethane, its solubility is quite good. Because organic solvents and molecules of the compound can form similar forces, such as van der Waals forces, dipole-dipole interactions, etc., solvent molecules can effectively surround solute molecules and disperse them uniformly in solution. However, in water, its solubility is not good, because the polarity of water and the polarity matching of the molecular structure of the compound are not good, it is difficult for water molecules to form a stable interaction with the compound molecules, and it cannot be dispersed in the system.
In terms of density, a specific value can be obtained by accurate measurement. This value reflects the mass of the compound per unit volume and is related to the degree of close packing of its molecules. If the degree of close packing is high, the density is large; otherwise, it is small. This property has important reference value in chemical production, drug research and development, and other fields, involving material dosage and volume calculation.
In addition, the stability of the compound cannot be ignored. Under general environmental conditions, it has a certain stability and the molecular structure is not easy to change spontaneously. However, under extreme conditions such as high temperature, strong acid, and strong alkali, its structure may change, triggering a chemical reaction. This stability is closely related to the strength of the chemical bonds in the molecule and the stability of the spatial structure.
What is the use of Ethyl 2-amino-7-isopropyl-5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate?
Ethyl + 2 - amino - 7 - isopropyl - 5 - oxo - 5H - [1] benzopyrano [2,3 - b] pyridine - 3 - carboxylate, Chinese name or 2 - amino - 7 - isopropyl - 5 - oxo - 5H - [1] benzopyrano [2,3 - b] pyridine - 3 - carboxylate. This compound is widely used in the field of medicine and is often used as an active ingredient to develop drugs for the treatment of specific diseases. Due to its special chemical structure and activity, or affinity to specific biological targets, it can regulate physiological processes in organisms and play a therapeutic role in some diseases.
In the field of organic synthesis, it is an important intermediate. Organic synthesizers prepare a series of derivatives by modifying and modifying their structures through various chemical reactions. The functional groups carried by this compound, such as amino groups and ester groups, can participate in various reactions, such as nucleophilic substitution, esterification, amidation, etc., which help to construct complex organic molecular structures and lay the foundation for the synthesis of new functional materials and total synthesis of natural products.
In the field of materials science, its derivatives may exhibit special optical, electrical and other properties, and are expected to be used in the preparation of optoelectronic materials. Its unique molecular structure may endow the material with specific light absorption and emission properties, and play a key role in the fabrication of optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells, enhancing device performance and efficiency.
Ethyl 2-amino-7-isopropyl-5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate
Ethyl+2-amino-7-isopropyl-5-oxo-5H-%5B1%5Dbenzopyrano%5B2%2C3-b%5Dpyridine-3-carboxylate, that is, 2-amino-7-isopropyl-5-oxo-5H-benzopyrano [2,3-b] pyridine-3-carboxylic acid ethyl ester, the synthesis method is as follows:
The starting material is selected from benzopyran compounds and pyridine derivatives. First take an appropriate amount of benzopyran compounds and place them in a clean reactor, and fully replace the air in the kettle with nitrogen to create an inert atmosphere to prevent the material from oxidizing. Add an appropriate amount of organic solvent, such as anhydrous dichloromethane, and stir well to fully dissolve the material.
Add the pyridine derivative slowly, and the dripping speed needs to be strictly controlled to prevent the reaction from being too violent. At the same time, add an appropriate amount of Lewis acid as a catalyst, such as aluminum trichloride, to promote the reaction. The reaction temperature is maintained at a low temperature state, about 0 - 5 ° C. This temperature range allows the reaction to occur smoothly and reduce side reactions. The reaction process is closely monitored by thin layer chromatography (TLC) during the reaction process.
When the reaction reaches the desired level, pour the reaction solution into ice water to quench the reaction. Subsequently, methylene chloride is extracted and extracted several times to ensure that the product is fully transferred to the organic phase. The organic phases are combined and dried with anhydrous sodium sulfate to remove the moisture.
After that, the organic solvent is removed by reduced pressure distillation to obtain a crude product. The crude product is further purified by column chromatography, and a suitable eluent, such as a mixture of petroleum ether and ethyl acetate, is selected. The ratio is adjusted according to the actual situation. After elution, collection and concentration, a pure 2-amino-7-isopropyl-5-oxo-5H-benzopyrano [2,3-b] pyridine-3-carboxylic acid ethyl ester product can be obtained. The whole synthesis process needs to strictly follow the operating procedures and pay attention to details to ensure the purity and yield of the product.
Ethyl 2-amino-7-isopropyl-5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate safety considerations
Ethyl 2 - amino - 7 - isopropyl - 5 - oxo - 5H - [1] benzopyrano [2,3 - b] pyridine - 3 - carboxylate is a chemical substance, and the following are the safety precautions in ancient sayings:
This is a chemical substance, which is related to safety and requires extreme caution. Its nature is unknown, or it may pose a risk of harm. When handling this object, wear protective gear, such as special robes, to prevent it from touching the skin and causing injury. You also need to wear a mask to prevent its volatile gas from entering the mouth and nose, so as not to damage the organs.
Place it in a dry and cool place, away from sources of fire and hot topics, lest it change due to heat and cause unexpected disasters. And do not mix with other things to prevent interaction and danger.
If you accidentally touch the skin, rinse it with water immediately, and then seek medical attention according to the severity of the injury. If it enters the eyes, rinse it with clean water immediately, and ask a doctor for urgent treatment.
When taking it, follow the precise method, do not overdo it, do not be hasty. After use, store it properly to prevent it from being left behind and endangering the surroundings. Those who work together should be aware of their interests and abide by the rules of safety, so that they can be protected.