Ethyl 2 6 Dichloro 5 Fluoro Oxo 3 Pyridine Propionate
pyridine pyrrole pyrazine piperidine piperazine

Ethyl 2,6-dichloro-5-fluoro-尾-oxo-3-pyridine propionate

    Specifications

    HS Code

    765653

    Chemical Name Ethyl 2,6 - dichloro - 5 - fluoro -γ - oxo - 3 - pyridine propionate
    Molecular Formula C10H9Cl2FNO3
    Molecular Weight 282.09
    Appearance Solid (usually white or off - white powder)
    Boiling Point N/A (decomposes before boiling)
    Melting Point 98 - 102 °C
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Odor Faint, characteristic odor
    Stability Stable under normal conditions, but sensitive to strong acids and bases

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    General Information
    Where to Buy Ethyl 2,6-dichloro-5-fluoro-尾-oxo-3-pyridine propionate in China?
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    Frequently Asked Questions

    As a leading Ethyl 2,6-dichloro-5-fluoro-尾-oxo-3-pyridine propionate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Ethyl 6-dichloro-5-fluoro- γ-oxo-3-pyridine propionate?
    Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate (2,6 - dichloro - 5 - fluoro - γ - - 3 - ethyl pyridyl propionate), this substance has a wide range of uses, in the field of agrochemical, often used as a key intermediate for the creation of new pesticides. Pesticides are related to the people's livelihood of the society, ensuring the abundance of grains, the prosperity of fruits and vegetables, the elimination of pests, the elimination of diseases, and the maintenance of ecological balance.
    In the field of pharmaceutical and chemical industry, it is also indispensable. Or as the starting material for the research and development of special new drugs, to conquer difficult diseases, heal the body and mind of patients, and lay the cornerstone. Medicine is the great cause of saving people and helping the world. This intermediate contributes to the development of good medicines, which is related to the health of all people.
    Furthermore, in the field of fine chemicals, it participates in the synthesis of many high-end fine chemicals. Fine chemical products, or used in frontier industries such as electronics and materials, promote scientific and technological progress and improve industrial standards. This intermediate is like a smart "factor", active in the complex network of fine chemicals, shaping a variety of high-end products.
    In short, Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate is small in size, but in the vast world of agrochemical, pharmaceutical, fine chemical industry, etc., with its unique structure and activity, exert extraordinary power, influence the development of the industry, far-reaching, like an unsung hero behind the scenes, silently promote the industry forward.
    What are the synthesis methods of Ethyl 6-dichloro-5-fluoro- γ-oxo-3-pyridine propionate
    Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate is an important organic compound. Its synthesis method has been explored by chemists throughout the ages.
    One method uses pyridine derivatives containing corresponding substituents as starting materials. The chlorine and fluorine atoms are introduced at specific positions of the pyridine ring first, which can be achieved by halogenation reaction. Appropriate halogenating reagents, such as chlorine and fluorine-containing halogenating agents, are selected to precisely halogenate the pyridine ring under suitable reaction conditions, such as specific temperatures and catalysts. Subsequently, ethyl γ-carbonyl propionate structure is constructed. A suitable functional group can be introduced into the side chain of the pyridine ring, and then converted into the ethyl gamma-carbonyl propionate moiety through a series of reactions. For example, a specific nucleophilic reagent reacts with the pyridine derivative to form the preliminary structure of the side chain, and then the side chain is perfected by oxidation, esterification and other steps, and the final target product is obtained.
    Another method is to construct the ethyl propionate skeleton first, and then introduce the pyridine ring. Using ethyl propionate derivatives containing suitable substituents as raw materials, by specific reactions, such as nucleophilic substitution, condensation, etc., the pyridine ring is gradually introduced into the ethyl propionate molecule, and chlorine, fluorine atoms and γ-carbonyl groups are precisely introduced into the pyridine ring at the same time. This process requires fine regulation of reaction conditions, such as reaction temperature, ratio of reactants, reaction time, etc., to ensure that each step of the reaction proceeds smoothly, and the product purity and yield are good.
    Furthermore, a multi-step tandem reaction strategy can also be used. Starting from simple raw materials, through careful design of reaction sequences and conditions, multiple reactions can occur in the same reaction system in sequence, and the complex structure of Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate can be directly constructed. In this way, cumbersome intermediate separation steps can be avoided, and the synthesis efficiency and atomic economy can be improved. However, this strategy requires more stringent reaction conditions, and requires in-depth understanding of the reaction mechanism and interaction of each step in order to achieve success.
    What are the physical and chemical properties of Ethyl 6-dichloro-5-fluoro- γ-oxo-3-pyridine propionate
    Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate is an organic compound. The physicochemical properties of this substance are as follows:
    Looking at its properties, it may be a solid under normal conditions, but the exact state depends on specific conditions. Its melting point and boiling point are both key physical properties. The melting point is the temperature at which a substance changes from a solid state to a liquid state. The melting point of this compound may vary depending on intermolecular forces and crystal structures. As for the boiling point, it is the temperature at which a substance converts from a liquid state to a gas state, which is determined by factors such as intermolecular attractive forces and molecular weight.
    Solubility is also an important property. In organic solvents, such as ethanol, acetone, etc., due to the principle of similar miscibility, or exhibit a certain solubility. Because the molecular structure of the compound contains polar and non-polar parts, it can interact with organic solvent molecules to form van der Waals forces or hydrogen bonds. However, in water, its solubility may be limited, due to the strong polarity of water, and the overall polarity of the compound is not well matched with water.
    From the perspective of chemical properties, the intra-molecular carbonyl group (γ-oxo part) has high reactivity. Carbonyl carbons are positively charged and are susceptible to attack by nucleophiles, such as nucleophilic addition reactions. For example, under the catalysis of acids or bases with alcohols, acetals or semi-acetals can be formed.
    Furthermore, the pyridine ring also affects its chemical properties. The pyridine ring has a certain aromaticity, and the electron cloud distribution on the ring is uneven. The chlorine atom at position 2 and 6 and the fluorine atom at position 5 change the electron cloud density on the ring, making the pyridine ring more prone to nucleophilic substitution. The ester group of the side chain is also typically reactive, and can undergo hydrolysis under the catalysis of acid or base to generate corresponding carboxylic acids and ethanol. When the alkali catalyzes hydrolysis, the reaction rate is faster, and the product is a carboxylate, which can be obtained after acidification.
    What is the price range of Ethyl 6-dichloro-5-fluoro- γ-oxo-3-pyridine propionate in the market?
    Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate is a fine chemical product. It is difficult to make a sudden conclusion in the market price category. This is because the price is often affected by many factors, just like the changing situation, unpredictable and unpredictable.
    First, the price of raw materials has a deep impact. If the supply of raw materials is sufficient and the price is stable, the price of the product may be relatively stable; however, if the raw materials are scarce, or the price rises for various reasons, the price of this product will also rise. If the origin of raw materials suddenly changes and the supply is blocked, the price will be like a wild horse, which is difficult to control.
    Second, the precision of the production process is closely related to the cost, which in turn affects the price. Advanced and efficient processes may reduce costs and increase efficiency, making the price more competitive; while backward and cumbersome processes, high costs, and prices will also rise.
    Third, the market supply and demand situation is also the key. If the market demand is strong and the supply is limited, just like the situation of too many monks and too little porridge, the price will go up; on the contrary, if the market oversupply and product backlog, the price will fall.
    Fourth, policies and regulations and environmental protection requirements will also indirectly affect the price. Stringent environmental protection policies may cause manufacturers to increase environmental protection inputs and increase costs, thereby driving up prices.
    As for its exact market price range, it is difficult to give an accurate value. Prices vary in different periods, regions, and transaction sizes. It is necessary to pay close attention to market dynamics and carefully observe changes in various factors in order to have a more accurate understanding of its price.
    Ethyl 6-dichloro-5-fluoro- γ-oxo-3-pyridine propionate
    Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - pyridine propionate, which is a specific compound in organic chemistry. Under the current chemical industry structure, many manufacturers are involved in the production of this compound.
    In Shandong, there is Shouguang Fukang Pharmaceutical Co., Ltd. This company is famous in the field of production of this compound with its exquisite chemical technology and profound research and development heritage. Its production process is rigorous and orderly, from the selection of raw materials to the precise control of reaction conditions, all follow strict standards to ensure high product quality.
    In the Zhejiang area, Zhejiang Yongtai Technology joint stock company is also an important manufacturer. Our company focuses on technological innovation, invests heavily in research and development, and continuously optimizes the production process. In the production process of this compound, it uses advanced equipment and cutting-edge technology to improve production efficiency and product purity, and the products produced are widely praised in the market.
    In the domain of Jiangsu, Nantong Taihe Chemical Joint Stock Company is also a powerhouse in the production of this compound. This company has accumulated many years of experience in the chemical industry and controls the details of the production process in place. From the operation of the reactor to the purification and refining of the product, it is strictly supervised by a professional team. The Ethyl 2,6 - dichloro - 5 - fluoro - γ - oxo - 3 - ridine propionate produced is of excellent quality and is supplied to many downstream enterprises.
    In addition, some manufacturers in Hubei are also involved in the production of this compound. For example, Hubei Xinmingtai Chemical Co., Ltd., which is actively involved in production by virtue of the rich local chemical resources and convenient transportation conditions. Although the scale may be inferior to the above-mentioned large factories, its products also have a certain market share, and have a firm foothold in the industry with flexible business strategies and reliable product quality.