Ethyl 1h Pyrrolo 3 2 B Pyridine 2 Carboxylate
pyridine pyrrole pyrazine piperidine piperazine

ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate

    Specifications

    HS Code

    515389

    Chemical Formula C10H10N2O2
    Molar Mass 190.2 g/mol
    Appearance Solid (predicted)
    Boiling Point Predicted to be relatively high due to presence of polar groups
    Melting Point No specific data found, but likely in solid - state at room temperature
    Solubility Soluble in polar organic solvents like ethanol, methanol (predicted due to polar groups)
    Density No experimental value, but predicted based on structure to be around 1.2 - 1.3 g/cm³
    Pka No experimental pKa data, but the pyrrolo - pyridine nitrogen can potentially be basic
    Refractive Index No experimental value, but prediction based on similar heterocyclic compounds possible
    Stability Should be stable under normal conditions, but may react with strong acids, bases or oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading ethyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate
    Ethyl + 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate is an organic compound. Its chemical structure can be summarized as follows:
    The core structure of this compound is 1H - pyrrolo [3,2 - b] pyridine, which is a fused heterocyclic system. It contains a pyrrole ring and a pyridine ring, which are fused in a specific way. Specifically, the nitrogen atom of the pyrrole ring (that is, the 1-position nitrogen atom) shares some atoms with the pyridine ring, forming a fused method of [3,2 - b].
    The ethyl carboxylate moiety is an ethyl ester group, which is connected to the 2-position of 1H-pyrrolo [3,2-b] pyridine. The structure of the ethyl ester group is -COOCH-CH, where -COO-is the characteristic structure of the ester group, which is connected to the 2-position of 1H-pyrrolo [3,2-b] pyridine, and -CH-CH-CH is ethyl.
    In summary, the chemical structure of ethyl 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate is composed of 1H - pyrrolo [3,2 - b] pyridine core heterocyclic ring system and ethyl ester group connected to the 2 - position. This unique structure endows the compound with specific physical and chemical properties, which may be of great significance in the fields of organic synthesis and medicinal chemistry.
    What are the main uses of ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate
    Ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate is an organic compound with a wide range of uses.
    In the field of pharmaceutical chemistry, this compound has a unique structure and can be used as a key intermediate in drug development. Due to its nitrogen heterocycle structure, such structures are often closely related to biological activities. Chemists can create new compounds with specific pharmacological activities by modifying their structures, such as inhibitors or agonists targeting specific disease targets, which paves the way for drug development.
    In materials science, this compound may be used to prepare functional materials. Its special chemical structure may endow materials with special optical and electrical properties. For example, introducing it into polymer materials by specific means may improve the conductivity of the materials, making the materials suitable for organic electronic devices, such as organic Light Emitting Diodes (OLEDs), organic field effect transistors, etc., contributing to the development of new materials.
    In the field of organic synthesis, ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate is an important synthetic building block. Because of its active reaction check point, chemists can use it to carry out various chemical reactions according to different reaction conditions and reagents, such as nucleophilic substitution, electrophilic addition, etc., to construct more complex organic molecular structures and provide effective starting materials for the synthesis of various organic compounds.
    What are the synthesis methods of ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate
    The method of synthesizing ethyl 1H-pyrrolo [3,2 - b] pyridine-2 - carboxylate is an important task in organic synthesis. There are many methods, and each has its advantages and disadvantages. The common ones are briefly described below.
    First, a suitable pyridine derivative is used as the starting material. A suitable substituent is introduced at a specific position of the pyridine ring first, and the pyrrole ring is constructed through a multi-step reaction. For example, a pyridine derivative and a reagent containing an appropriate functional group can be carried out under a specific catalyst and reaction conditions to carry out a nucleophilic substitution reaction to introduce a group that can further react to form a pyrrole ring. Subsequently, under appropriate acid-base conditions and temperatures, the intramolecular ring is formed, and the pyrrolido-pyridine structure is constructed. After esterification, the ethyl ester group is introduced at the 2-position carboxyl group to obtain the target product. In this process, the choice of catalyst and the control of reaction conditions are extremely critical, such as temperature, reaction time and ratio of reactants, which all affect the yield and selectivity of the reaction.
    Second, pyrrole derivatives can also be used as starters. First, the pyrrole ring is modified to introduce the group required for the pyridine ring. For example, by using pyridine-related reagents, in a suitable reaction system, the pyridine ring is formed by cyclization. Then, the carboxyl group is esterified to obtain ethyl 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate. This route requires precise design of reaction steps to ensure the smooth progress of each step and avoid unnecessary side reactions.
    Third, there is a strategy to use metal-catalyzed reactions. Using small molecules containing pyridine and pyrrole structural fragments as raw materials, under the action of metal catalysts, the two are connected and the target structure is constructed through cross-coupling reactions. Metal catalysts can effectively promote the reaction, improve reaction efficiency and selectivity. However, the cost and post-treatment of metal catalysts also need to be considered to ensure the economy and feasibility of the synthesis route.
    In conclusion, there are various methods for synthesizing ethyl 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate. In actual operation, many factors such as the availability of raw materials, cost, difficulty in controlling reaction conditions and yield need to be comprehensively considered to select the most suitable synthesis path.
    What are the physical properties of ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate
    Ethyl 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate is an organic compound, and its physical properties are quite characteristic. In appearance, this compound is often white to quasi-white crystalline powder, like fine snow, fine texture, or shimmering under light. Looking at its color, the pure color is white and flawless, but when some impurities are mixed in, it may appear slightly yellow.
    When it comes to the melting point, it is about a specific temperature range, which is one of the key indicators for the identification of this compound. Its melting point is relatively stable, like a fixed nautical needle. Measured under established conditions, it can obtain a more accurate value, which can help researchers determine its purity and characteristics.
    In terms of solubility, it shows good solubility in organic solvents such as dichloromethane and chloroform, just like fish entering water and rapidly blending. However, the solubility in water is not good, just like oil and water are difficult to blend, and this property is closely related to the distribution of hydrophilic groups in its molecular structure.
    Furthermore, the density of the compound is also a specific value. This physical quantity reflects the degree of close arrangement of its molecules, just like the microscopic order inside the substance, which affects its behavior in different environments.
    Its stability is acceptable under normal conditions. When it encounters a hot topic, an open flame or a strong oxidant, the stability drops suddenly, just like a calm lake throwing boulders into the lake, triggering a chain reaction. This feature warns researchers to take extra care during storage and use to ensure safety. In conclusion, the physical properties of Ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate are complex and interrelated, laying the foundation for further research and application.
    What is the market outlook for ethyl 1H-pyrrolo [3,2-b] pyridine-2-carboxylate
    Ethyl + 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate, Chinese name or 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate. Looking at its market prospects, this compound may have potential in the field of pharmaceutical research and development.
    In today's pharmaceutical research, new active ingredients are often found to make specific drugs. 1H - pyrrolo [3,2 - b] pyridine - 2 - carboxylate ethyl ester contains a unique nitrogen heterocyclic structure, which often gives compounds a variety of biological activities, such as anti-tumor, antiviral, anti-inflammatory, etc. Therefore, in the process of creating innovative drugs, it may be a key intermediate, attracting the attention of many pharmaceutical companies and scientific research institutions.
    In the field of materials science, organic compounds with special structures are often the cornerstones of building novel functional materials. The structural properties of 1H-pyrrolido [3,2-b] ethyl pyridine-2-carboxylate may make it stand out in the fields of optoelectronic materials, such as the preparation of organic Light Emitting Diodes, solar cell materials, etc., with its unique electronic structure and optical properties to improve material properties.
    However, its marketing activities also encounter challenges. Synthesis of the compound may require complex steps and special reagents, resulting in high production costs. Only by overcoming the synthesis difficulties and clarifying the pharmacological and toxicological properties can 1H-pyrrolido [3,2-b] pyridine-2-carboxylate ethyl ester shine in the market and bring innovation to the field of medicine and materials.