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What are the chemical properties of Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate
Ethyl-1H-pyrrolido [2,3-c] pyridine-5-carboxylic acid ester, this is an organic compound. Looking at its chemical properties, it has the general properties of esters. Esters can be hydrolyzed slowly in contact with water, and in acidic environments, the hydrolysis is reversible. The reaction formula is roughly as follows: RCOOR '+ H ² O RCOOH + R'OH. This compound should also be hydrolyzed according to this principle to produce 1H-pyrrolido [2,3-c] pyridine-5-carboxylic acid and ethanol. In alkaline environments, hydrolysis tends to be complete, resulting in carboxylic acid and alcohol. Because the base can react with the generated carboxylic acid, the equilibrium shifts to the right. < Br >
and because of its pyridine ring and pyrrole ring structure, pyridine ring has a certain basic, the lone pair of electrons on the nitrogen atom can accept protons and can form salts with acids; pyrrole ring has a certain aromaticity and electrophilic substitution activity. Under appropriate conditions, electrophilic substitution reactions such as halogenation, nitrification, sulfonation, etc. can occur, and the substitution check point is mostly in the higher density of the electron cloud. The hydrogen of the nitrogen atom on the pyrrole ring has a certain acidity and can react with strong bases.
In addition, the compound contains a conjugated system, which causes it to have a characteristic absorption peak in the ultraviolet-visible spectrum in terms of spectral properties, which can be used for identification and quantitative analysis. The spatial arrangement and electron cloud distribution of atoms in molecules also affect their physical and chemical properties, and play an important role in the chemical reaction pathways and product structures they participate in.
What are the synthesis methods of Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate
There are many common methods for synthesizing Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate (1H-pyrrolo [2,3-c] pyridine-5-carboxylate).
First, it can be prepared by specific condensation reaction from raw materials containing pyridine and pyrrole structures. For example, using suitable pyridine derivatives and pyrrole derivatives as starting materials, under specific catalysts and reaction conditions, the two condensation occurs. In the meantime, the choice of catalyst is very important, or a Lewis acid catalyst is used to promote the reaction process, so that the intermolecular bonding can gradually build the specific structure of the target product. The reaction environment also needs to be controlled, and factors such as temperature and solvent will affect the reaction rate and yield.
Second, through a multi-step reaction, one of the pyridine rings or pyrrole rings can be constructed first, and then the other ring structure can be introduced. For example, the pyridine ring is synthesized by a common organic synthesis method, with functional groups that can be further reacted on it. Then, with suitable reaction conditions, the pyrrole ring part is introduced, and the synthesis of the target molecule is finally achieved. In this process, the order and conditions of each step of the reaction need to be carefully regulated to prevent side reactions from occurring and the yield from decreasing.
Third, there are also methods of chemical modification and transformation using natural products as starting materials. If there are natural products containing similar structural fragments, the synthesis of Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate can be gradually led by modifying and transforming the functional groups at specific positions. This approach may take advantage of the inherent structural advantages of natural products to simplify some synthesis steps, but there are also corresponding requirements for the acquisition and pre-treatment of natural products.
The synthesis process requires careful selection of suitable synthesis methods according to the availability of raw materials, the difficulty of reaction, cost considerations and many other factors, in order to achieve the purpose of efficient synthesis.
What is the main use of Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate?
Ethyl-1H-pyrrolido [2,3-c] pyridine-5-carboxylate has a wide range of uses. In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of many biologically active drugs. Due to its unique chemical structure, it can impart specific properties to drug molecules, such as good affinity with specific targets in vivo, which helps to develop effective therapeutic drugs for specific diseases, such as anti-inflammatory and anti-tumor drugs.
In the field of organic synthesis chemistry, ethyl-1H-pyrrolido [2,3-c] pyridine-5-carboxylate also plays an important role. It can be connected with other organic molecules through various chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc., to construct complex and diverse organic compounds, providing an effective starting material for organic synthesis chemists to explore novel compound structures and properties.
In addition, in the field of materials science, compounds containing this structure may exhibit unique photoelectric properties after appropriate modification, or can be applied to the preparation of organic Light Emitting Diodes, solar cells and other materials, which contributes to the development of materials science. From this perspective, ethyl-1H-pyrrolido [2,3-c] pyridine-5-carboxylic acid esters have important value and wide application prospects in many scientific fields.
What is the market outlook for Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate?
Ethyl 1H-Pyrrolo [2,3-c] Pyridine-5-Carboxylate, which is an organic compound, can be called 1H-pyrrolo [2,3-c] pyridine-5-carboxylic acid ethyl ester in Chinese. To explore its market prospects, many aspects need to be looked at.
Looking at the current pharmaceutical field, many innovative drug research and development have a growing demand for characteristic heterocyclic structures. Ethyl 1H-pyrrolo [2,3-c] pyridine-5-carboxylate contains a unique pyrrolido-pyridine structure, which often has good biological activity and pharmacological properties in pharmaceutical chemistry. For example, in the development of some anti-cancer drugs, such heterocyclic structures can be used as key pharmacopharmaceuticals, modified and optimized, and may be able to develop new and efficient anti-cancer drugs. Therefore, at the forefront of pharmaceutical research and development, it may have a broad application space, and market demand is expected to grow with the advancement of new drug research and development.
Looking at material science, organic functional materials are developing rapidly. Compounds containing specific heterocycles can be rationally designed and synthesized, giving materials special photoelectric properties. 1H-pyrrolido [2,3-c] ethyl pyridine-5-carboxylate may participate in the preparation of new photoelectric materials, such as organic Light Emitting Diode (OLED) materials, solar cell materials, etc. With the booming development of electronic equipment and new energy industries, the demand for high-performance organic materials is rising, and this compound may also find opportunities for development in the materials market.
However, its marketing activities also face challenges. Synthesis of the compound may require complex steps and specific conditions, the cost may be high, limiting large-scale application. And the entry of new compounds into the market requires strict safety and performance evaluation, which is time-consuming and laborious. But over time, with the optimization of the synthesis process, cost reduction, and in-depth application research, Ethyl 1H-Pyrrolo [2,3-c] Pyridine-5-Carboxylate in the fields of medicine and materials or shine, opening up a broad market.
Ethyl 1H-Pyrrolo [2,3-C] Pyridine-5-Carboxylate Precautions during storage and transportation
Ethyl 1H - Pyrrolo [2,3 - c] Pyridine - 5 - Carboxylate is an organic compound. When storing and transporting, pay attention to the following things:
First, the storage environment must be dry and cool. This compound is afraid of moisture and high temperature. If it is in a humid place, it may cause chemical reactions such as hydrolysis, which will damage its purity and quality. High temperature will also accelerate its chemical change. Therefore, it should be stored in a dry, cool and well-ventilated place. The temperature should be maintained at 5 ° C to 25 ° C.
Second, it must be tightly packed. Due to its nature or more active, it can be exposed to air for a long time, or react with oxygen, water vapor, etc. in the air. It needs to be stored in a sealed container. Glass or special plastic containers are often used to ensure that the packaging is not at risk of leakage to maintain its chemical stability.
Third, during transportation, avoid violent vibration and collision. The compound structure may have a certain vulnerability, violent vibration, collision or damage to the packaging, and may cause internal structural changes, affecting its chemical properties. The transportation vehicle should run smoothly to reduce bumps.
Fourth, it must be isolated from oxidizing agents, acids, alkalis and other chemicals. The chemical properties of Ethyl 1H - Pyrrolo [2,3 - c] Pyridine - 5 - Carboxylate determine that it is easy to chemically react with these substances, causing hazards such as combustion and explosion. During storage and transportation, it should never be mixed with such chemicals.
Fifth, do a good job of marking. Whether it is storage containers or transportation packaging, the name, nature, and hazard precautions of the compound should be clearly marked so that relevant personnel know that in the event of an emergency, they can quickly take correct measures according to the marking information to ensure the safety of personnel and the environment.