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What is the chemical structure of ethyl 1H-pyrrolo [2,3-c] pyridine-2-carboxylate
Alas! If you want to know the chemical structure of ethyl + 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate, please listen to me in detail.
The name of this compound, ethyl means ethyl, indicating that its structure contains this group. In this part of 1H - pyrrolo [2,3 - c] pyridine, pyrrolo means pyrrole, [2,3 - c] indicates the fusing method of pyrrole ring and pyridine ring, which is connected according to this rule to form a specific fused ring structure. And - 2 - carboxylate indicates that there are carboxylate groups connected at the second position of the fused ring. < Br >
Its structure is roughly as follows. First, there is a parent nuclear structure formed by fusing the pyrrole ring with the pyridine ring. At position 2 of the pyrrole-pyridine ring, a carboxylic acid ester group is connected, and this ester group contains ethyl. It is like a delicate chemical building. The groups are connected in a random manner according to specific rules, forming this unique chemical structure and demonstrating the wonders and delicacies of the chemical world.
What are the main uses of ethyl 1H-pyrrolo [2,3-c] pyridine-2-carboxylate
Ethyl 1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid ester has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate and helps in the synthesis of many drugs. Many new antidepressant drugs use it as the base material to derive compounds with specific pharmacological activities through delicate chemical reactions. Because of its unique chemical structure, it can effectively participate in and promote the reaction process, accurately construct the key parts of drug molecules, and is of great significance to drug research and development.
In the field of materials science, ethyl 1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid ester is also useful. In the preparation of special functional organic materials, it can be used as a structural modification unit. By ingeniously introducing this substance, the photoelectric properties of the material can be significantly improved, such as enhancing the fluorescence properties of the material and improving its charge transport efficiency. In this way, it plays an indispensable role in the research and production of cutting-edge materials such as organic Light Emitting Diodes and solar cells.
In addition, in the field of fine chemicals, it is used as an important raw material for the synthesis of high-end fine chemicals. Such as some special fragrances, additives, etc., after rational chemical transformation, it endows the product with unique properties and quality, meets the specific needs of different industries, enhances the added value of the product, and injects vitality into the development of the fine chemical industry.
What are the synthesis methods of ethyl 1H-pyrrolo [2,3-c] pyridine-2-carboxylate
To prepare ethyl 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate, there are many methods, each with its own advantages. In the past, various sages have diligently studied the way of organic synthesis, and left many wonderful methods for future generations.
First, the corresponding nitrogen-containing heterocyclic precursor and ethyl carboxylate derivatives can be replaced by nucleophilic substitution under specific conditions. First, the active check point on the nitrogen-containing heterocyclic ring initiates a nucleophilic attack on the carbonyl α-carbon of ethyl carboxylate, and then goes through a series of steps such as proton transfer and elimination, and then becomes the target product. This process requires careful selection of solvents, such as aprotic polar solvents, such as DMF, DMSO, etc., because it can promote the activity of nucleophiles and stabilize the reaction intermediates. At the same time, temperature control is also crucial. Under moderate heating conditions, the reaction can proceed smoothly, and it should not be overheated to avoid side reactions.
Second, the method of metal catalysis is also quite desirable. Choose suitable metal catalysts, such as palladium, copper, etc., and use their unique catalytic activity to couple nitrogen-containing heterocycles with ethyl halocarboxylate. Among these, the combination of metal catalysts and ligands is crucial, and delicate ligands can enhance the selectivity and activity of metal catalysts. In the reaction system, the presence of alkali is indispensable, which can assist in the activation of halogenates and promote the progress of the reaction. The reaction environment needs to be strictly anhydrous and oxygen-free to prevent the metal catalyst from deactivating and affecting the reaction effect.
Third, the target molecule can be constructed by multi-step reaction. First, the nitrogen-containing heterocyclic skeleton is constructed from the basic raw material, and then the carboxylic acid ethyl ester group is introduced at a suitable stage. This strategy requires fine regulation of the reaction conditions of each step to ensure the yield and selectivity of each step, and then to achieve the purpose of final synthesis. After each step of the reaction, it needs to be separated and purified to remove impurities and provide pure raw materials for subsequent reactions.
All these synthesis methods require the experimenter to carefully investigate the reaction mechanism and fine-tune the reaction conditions in order to obtain satisfactory results in the synthesis of ethyl 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate.
What are the physical properties of ethyl 1H-pyrrolo [2,3-c] pyridine-2-carboxylate
Ethyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid ester, this is an organic compound with specific physical properties.
Its properties are usually solid, but the specific physical state will vary depending on the purity and environmental conditions. In terms of melting point, the melting point of the substance with different preparations and purity may vary, but it is usually in a certain temperature range, which is critical for determining its purity and characteristics.
In terms of solubility, the substance exhibits different solubility in organic solvents. In common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), it often has good solubility, which makes it convenient to select suitable solvents for reaction, separation and purification in organic synthesis operations. However, in water, its solubility is poor, because the hydrophobic part of the molecular structure of the compound accounts for a large proportion, resulting in weak interaction with water molecules.
In addition, the density of ethyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylic acid ester is also an important physical property. Although the exact density value needs to be accurately determined experimentally, it can be inferred that its density may be similar to that of common organic compounds based on its molecular composition and structural characteristics. This property is of great significance in processes such as volume and mass conversion and mixture separation.
Its boiling point is also affected by factors such as intermolecular forces and relative molecular weights. Under a specific pressure, ethyl-1H-pyrrolido [2,3-c] pyridine-2-carboxylate will reach a specific boiling point, which is of great guiding value for operations such as distillation and separation.
What is the market outlook for ethyl 1H-pyrrolo [2,3-c] pyridine-2-carboxylate
Nowadays, ethyl + 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate has many reasons for its market situation. This compound is in the field of pharmaceutical research and development, and may have potential uses. The structure of 1H - pyrrolo [2,3 - c] pyridine often has unique biological activities, which can be the key parent nucleus for the creation of novel drug molecules. If ethyl + 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate can show good pharmacological properties, such as high efficiency and low toxicity, and strong target specificity, it will attract the attention of pharmaceutical companies and researchers, and the market prospect will be broad.
In the field of materials science, it may also have something to do. Some nitrogen-containing heterocyclic compounds can be used as functional materials, such as optoelectronic materials, after appropriate modification. If ethyl + 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate has unique characteristics in optical and electrical properties, or can be applied to organic Light Emitting Diodes, solar cells and other fields, market demand is also expected to increase.
However, its market prospects are also restricted by various factors. The difficulty of the synthesis process is related to the production cost. If the synthesis steps are cumbersome and harsh conditions, resulting in high costs, it will be unfavorable for large-scale production and marketing activities. Furthermore, regulations and market competition are also key. New drug research and development needs to be strictly approved, and the application of new materials also needs to meet relevant standards. And the competition of similar or alternative products in the market is fierce. If ethyl + 1H - pyrrolo [2,3 - c] pyridine - 2 - carboxylate does not have an outstanding advantage, it may be difficult to seize the market opportunity.