ethyl 1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 1H - pyrazolo [3,4 - c] pyridine - 3 - carboxylate is the Chinese name 1H - pyrazolo [3,4 - c] pyridine - 3 - carboxylate. The chemical structure of this compound can be explained by its name. "Ethyl" indicates that it contains an ethyl ester group, that is, a structural fragment of - COOCH < unk > CH < unk >. This fragment is an ester functional group, and the carbon atom of the ethyl ester group is connected to the rest of the molecule. "1H - pyrazolo [3,4 - c] pyridine" indicates that its core structure is a pyrazolo-pyridine thick ring system. The pyrazole ring fuses with the pyridine ring in a specific manner, where "[3,4-c]" indicates the positional relationship between the pyrazole ring and the pyridine ring. Specifically, the carbon atoms at positions 3,4 of the pyrazole ring are connected to the specific carbon atoms of the pyridine ring to form a fused ring. At position 3 of the fused ring system, the above-mentioned ethyl ester group is connected, namely - COOCH -2 CH < unk >. 1H - indicates that the 1 position of the pyrazolo ring is occupied by a hydrogen atom. In summary, the chemical structure of ethyl 1H - pyrazolo [3,4 - c] pyridine - 3 - carboxylate is an organic compound with a pyrazolopyridine fused ring as the core, an ethyl ester group at position 3, and a hydrogen atom at position 1.

Ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylate, Chinese name ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylate, this compound has a wide range of uses.
In the field of pharmaceutical chemistry, it is often used as a key intermediate. Because the structure of pyrazolo-pyridine exists in many bioactive molecules, it can participate in the construction of compounds with specific pharmacological activities. Taking the development of new anti-tumor drugs as an example, chemists can modify the structure of the compound and access different active groups to create new drugs that have targeted inhibitory effects on tumor cells. Or in the development of anti-inflammatory drugs, use its structural properties to design drugs that can regulate inflammation-related signaling pathways.
In the field of materials science, ethyl 1H-pyrazolo [3,4 - c] pyridine-3-carboxylate may be involved in the preparation of functional materials. For example, in the preparation of organic optoelectronic materials, its special structure may endow the materials with unique optoelectronic properties, such as adjusting the wavelength of the material, improving the fluorescence quantum efficiency, etc., to help prepare better Light Emitting Diode (OLED) materials for the manufacture of high definition display screens.
The compound also has potential applications in the field of pesticide chemistry. New pesticides can be developed based on their structure, and by virtue of their special mechanism of action against certain pests or pathogens, high-efficiency, low-toxicity, and environmentally friendly pesticides can be created, which can not only effectively control crop pests and diseases, but also reduce the harm to the environment and non-target organisms.

The synthesis method of fuethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid esters is one of the important topics in organic synthetic chemistry. There are many methods, and I will describe one of them in detail today.
First take the appropriate pyridine derivative, which is the starting material for the reaction. In a specific reaction vessel, add the pyridine derivative, and add an appropriate amount of base. The function of the base is to form an active check point at a specific position of the pyridine derivative, which is convenient for subsequent reactions. The choice of base is quite critical, depending on the specific conditions of the reaction and the characteristics of the raw materials. Common ones are potassium carbonate, sodium carbonate, etc.
Next, add reagents containing the structure of pyrazole. This reagent undergoes nucleophilic substitution reaction with alkali-activated pyridine derivatives. During the reaction, the reaction temperature and reaction time need to be strictly controlled. If the temperature is too low, the reaction rate will be slow and it will be difficult to achieve the desired effect; if the temperature is too high, it may breed side reactions and affect the purity of the product. Generally speaking, the reaction temperature is mostly controlled in a moderate range, such as 50-100 degrees Celsius. The reaction time also needs to be precisely controlled, ranging from a few hours to more than ten hours. Depending on the reaction process, it can be monitored by thin-layer chromatography and other means.
After the nucleophilic substitution reaction is completed, the product needs to be further processed. The initial separation and purification of the product is often carried out by extraction, washing, etc. When extracting, a suitable organic solvent is selected to enrich the product in the organic phase and The washing step can remove the residual alkali and other water-soluble impurities in the product.
Subsequently, the preliminarily purified product is separated by column chromatography. Column chromatography is a fine separation method commonly used in organic synthesis, which can effectively separate the product from other trace impurities to obtain high-purity ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid ester. Select an appropriate silica gel as the stationary phase and match it with a suitable eluent to achieve the final purification of the product according to the difference in the partition coefficient between the product and the impurities in the stationary phase and the eluent. In this way, the target product can be obtained, which is a synthetic method of ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylate.

Ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid ester, this is an organic compound. Its physical properties are crucial and related to its application in many fields.
Looking at its properties, under normal temperature and pressure, it is mostly in a solid state, but it also varies according to specific conditions. The melting point of this compound, under specific conditions, or within a certain range. The melting point, the temperature at which a substance changes from a solid state to a liquid state, is a key indicator for the identification and purification of the compound.
As for the boiling point, it is also an important physical property. The determination of the boiling point can help us know at what temperature the compound converts from a liquid state to a gaseous state. This property is indispensable in separation and purification operations such as distillation.
In terms of solubility, ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylic acid esters exhibit different solubility in organic solvents. In some organic solvents, such as common ethanol and acetone, it may have good solubility, but in water, it may have poor solubility. This difference in solubility has far-reaching effects on chemical reactions, separation processes, and drug formulations.
In addition, its density is also an important consideration. Density reflects the mass per unit volume of the compound and is a key parameter in scenarios involving material measurement, reaction system design, etc.
Its appearance is either white to off-white powder or crystalline solid, and this appearance characteristic is also the basis for preliminary identification of the compound.
Overall, the physical properties of ethyl 1H-pyrazolo [3,4-c] pyridine-3-carboxylate, such as melting point, boiling point, solubility, density and appearance, are of great significance to its research, application and treatment, and must be known by practitioners in related fields.

Ethyl + 1H-pyrazolo [3,4-c] pyridine-3-carboxylate is 1H-pyrazolo [3,4-c] pyridine-3-carboxylate, which is worth exploring in the current market prospect.
Looking at its market, in recent years, the field of pharmaceutical research and development has paid more and more attention to nitrogen-containing heterocyclic compounds. 1H-pyrazolo [3,4-c] pyridine-3-carboxylate, as an important nitrogen-containing heterocyclic derivative, has emerged in the creation of new drugs. Many scientific research teams have focused on its biological activity, and after many experiments and studies, they have found that it has potential application value in many pharmacological activities such as anti-cancer and anti-inflammatory.
Pharmaceutical companies are gradually observing its potential, or increasing investment in the research and development of this compound, with the intention of developing innovative drugs with high efficacy and low side effects. In this context, the market demand for 1H-pyrazolo [3,4 - c] pyridine-3-carboxylate ethyl ester is expected to rise.
However, the market prospect is not completely bright. The complex synthesis process and high cost set obstacles for industrial production. If a more efficient and economical synthesis path cannot be found, large-scale production and marketing activities of products will be hindered. At the same time, the pharmaceutical R & D cycle is long and high-risk, and there are many variables in the successful development of new drugs, which also adds uncertain factors to the market prospect.
In summary, although 1H-pyrazolo [3,4-c] pyridine-3-carboxylate ethyl ester presents potential development opportunities in the field of pharmaceutical R & D, it is necessary to overcome the problems of synthesis process and R & D risks in order to open up broad market prospects.