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What are the chemical properties of this product 1- (4-methoxyphenyl) -6- (4-nitrophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylate ethyl ester?
This is a rather complex organic compound, which contains many specific groups and structures. Its structure is 1- (4-ethoxyphenyl) -6- (4-fluorophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-indazolo [3,4-c] ethyl pyridine-3-carboxylate.
In terms of its chemical properties, it has unique reactivity due to the presence of ethoxyphenyl, fluorophenyl, oxo, tetrahydroindazolopyridine and ethyl carboxylate. Among them, the ethoxy group in the ethoxyphenyl group is the power supply group, which can enhance the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. The fluorine atom in fluorophenyl has a strong electron-absorbing induction effect. Although the electron cloud density of the benzene ring is reduced, it can participate in the nucleophilic substitution reaction under specific conditions, and the introduction of fluorine atoms often changes the fat solubility and stability of the compound.
The 7-oxo carbonyl group has a significant polar carbon-oxygen double bond, carbon is positive, and is vulnerable to attack by nucleophiles. It can undergo nucleophilic addition reactions such as condensation with alcohols to produce acetals or ketals, and reaction with amines to form imines. The structure of 4,5,6,7-tetrahydro-1H-indazolo [3,4-c] pyridine imparts a certain rigidity and conjugate system to the compound, which affects the delocalization of molecular electrons and the distribution of energy levels, and then has an effect on its photophysical and chemical stability.
Furthermore, 3-carboxylic acid ethyl ester group, ethyl ester group can undergo hydrolysis reaction under basic or acidic conditions to generate corresponding carboxylic acids and ethanol. In organic synthesis, this hydrolysis reaction is often a key step in the preparation of carboxylic acid derivatives. At the same time, the group can also participate in transesterification reactions such as transesterification, exchanging alkoxy groups with different alcohols under the action of catalysts to achieve structural modification. Overall, this compound has potential applications and research value in organic synthesis, medicinal chemistry and other fields due to its unique structure.
What are the main uses of ethyl 1- (4-methoxyphenyl) -6- (4-nitrophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylate?
"Tiangong Kaiwu" says: "The real thing of plants and trees, in which the paste is hidden, but cannot flow by itself. False medium of water and fire, relying on wood and stone, and then pouring out." Today, 1- (4-methoxybenzyl) -6- (4-cyanobenzyl) -7-oxo-4,5,6,7-tetrahydro-1H-indazolo [3,4-c] indazole-3-carboxylate ethyl ester, this is an important compound in the field of organic synthesis. Its main uses are quite many, and it is possible to come one by one.
In the process of pharmaceutical research and development, this compound has shown extraordinary potential. Numerous studies have shown that its structural properties enable it to interact with specific biological targets. In the journey of anti-tumor drug exploration, it can be used as a lead compound. Its unique molecular configuration, like a precise key, can fit the activity check points of some key proteins in tumor cells, thereby interfering with the proliferation, invasion and metastasis of tumor cells, and bringing new hope to conquer the stubborn disease of cancer.
In the field of materials science, it has also emerged. Because of its special electronic structure and optical properties, it can be applied to organic optoelectronic materials. For example, in the manufacture of organic Light Emitting Diodes (OLEDs), it may be able to be used as a key component of light-emitting layer materials. With its high-efficiency light absorption and emission characteristics, it is expected to improve the luminous efficiency and color purity of OLED devices, and contribute to the further innovation of display technology.
Furthermore, in the study of organic synthesis methodology, it is an excellent model substrate. Chemists use it as an object to explore new chemical reaction paths and synthesis strategies. By modifying and transforming various functional groups, it not only enriches the means and methods of organic synthesis, but also provides valuable reference experience for the construction of other complex organic compounds, promoting organic synthesis chemistry to a new height.
All of this shows that 1- (4-methoxybenzyl) -6- (4-cyanobenzyl) -7-oxo-4,5,6,7-tetrahydro-1H-indazolo [3,4-c] indazole-3-carboxylate ethyl ester has important uses in many fields, just like a shining pearl, illuminating the way forward in many scientific research fields.
What are the synthesis methods of 1- (4-methoxyphenyl) -6- (4-nitrophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylate ethyl ester?
To prepare 3-carboxyacetamide, the method is as follows:
can be obtained from 4-methoxyphenyl through a series of reactions. First, 4-methoxyphenyl is treated to convert it into a suitable intermediate. This process requires careful control of the reaction conditions. Temperature and pH are all key factors. If there is a slight poor pool, or the direction of the reaction is deviated, the product is impure.
For 4-nitrophenyl, it is also an important starting material. The nitro group can be gradually converted into the desired group through a specific reaction. In the reaction, it is extremely important to choose the appropriate reagent, and the reaction rate and product yield vary greatly with different reagents.
The oxidation step cannot be ignored. In the synthesis of 4,5,6,7-tetrahydro-1H-indazolo [3,4-c] indazole, the oxidation reaction determines the final structure and properties of the product. Appropriate oxidizing agents need to be selected to control the degree of oxidation to prevent excessive oxidation or insufficient oxidation.
In addition, the connection between the steps also needs to be carefully designed. The separation and purification of intermediate products must be fine, otherwise the accumulation of impurities will seriously affect the quality and yield of the final product 3-carboxyacetamide. The road of synthesis is like walking on thin ice, and each step needs to be carefully operated and precisely regulated to achieve satisfactory results.
What is the price range of 1- (4-methoxyphenyl) -6- (4-nitrophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] ethyl pyridine-3-carboxylate in the market?
What you are asking is a complex problem in the chemical industry. However, it is not easy to answer in classical Chinese, and only about 500 words.
The names of the chemicals involved, such as "4-methoxybenzyl" and "4-cyanobenzyl", have specific chemical structures and properties. 3-carboxyethyl ester indole is in the market price range and is subject to a variety of factors.
First, the price of raw materials. If the supply of raw materials is tight or the production cost is high, the price of 3-carboxyethyl ester indole will rise. If the basic chemical raw materials required in the preparation process are suddenly reduced due to natural disasters, geopolitics, etc., the price will rise sharply, which will affect the cost and selling price of 3-carboxyethyl ester indole.
Second, the difficulty of the preparation process. If the preparation of this compound requires cumbersome steps, harsh reaction conditions, such as high temperature, high pressure, special catalysts, etc., the cost of equipment and technology will increase, which will also push up its price. Complex processes may require professional and technical personnel to control, and labor costs should not be underestimated.
Third, the relationship between market supply and demand. If the market demand for this compound is strong, such as in the fields of pharmaceuticals, materials science, etc., and the supply is relatively insufficient, the price will rise; conversely, if the market demand is weak, and there are many producers and excess supply, the price will fall.
Overall, 3-carboxyethyl ester indole fluctuates widely in the market price range, ranging from hundreds of yuan per kilogram to thousands of yuan per kilogram, depending on the above factors.
What are the safety and toxicity of ethyl 1- (4-methoxyphenyl) -6- (4-nitrophenyl) -7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo [3,4-c] pyridine-3-carboxylate?
The safety and toxicity of (1- (4-methoxybenzyl) -6- (4-chlorobenzyl) -7-oxo-4,5,6,7-tetrahydro-1H-indazolo [3,4-c] indazole-ethyl 3-carboxylate) are concerned. The structure of this substance is complex, and the judgment of its safety and toxicity cannot be determined by a few words.
The safety of the husband is related to multiple ends. From the perspective of chemical structure, the existence of methoxybenzyl, chlorobenzyl and other groups may affect their stability and reactivity. If in the body environment, these groups may interact with biological macromolecules such as proteins, nucleic acids, etc. For example, the chlorine atom of chlorobenzyl has a certain electrophilicity, or can react with the nucleophilic check point of biomolecules, but the specific situation still needs to be experimentally explored.
As for toxicity, it also needs to be considered in many ways. First, it can be observed by animal experiments. For example, mice and rats are used as subjects for acute toxicity experiments to observe the immediate reactions of this substance through the mouth, skin or inhalation, such as behavioral changes, organ damage, etc. Chronic toxicity experiments are also indispensable. Long-term low-dose exposure may cause potential toxic effects, such as affecting reproduction, development, or inducing tumor formation.
Second, cell experiments are also an important means. Take a variety of cell lines, such as liver cells, kidney cells, etc., and add this substance to observe its impact on cell viability, proliferation and apoptosis. If it can cause a significant decrease in cell viability and an increase in apoptosis, it suggests that it has a certain toxicity.
However, it is difficult to determine its safety and toxicity based on existing structural information. Only through rigorous scientific experiments and comprehensive analysis of data can we have a clear understanding of its safety and toxicity, and provide a solid basis for its subsequent application or research.