(E)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester

Solution of "Tianwen Creation": This is a structural inference problem derived from the naming of organic compounds. According to the naming rules, gradually analyze the designation of each group to clarify its chemical structure.
" (E) -4 - [2 - [3 - (1, -dimethylethoxy) -3 -oxo-1-propynyl] benzyl] -1,4 -dihydro-2,6 -dimethyl-3,5 -diethyl benzoate".
First look at " (E) ", which is the configuration label of the olefin double bond, indicating the trans position of the larger group on both sides of the double bond. "4 -" shows that a specific substituent is attached to the 4th position of the main chain.
"In [2- [3- (1, -dimethylethoxy) -3 -oxo-1-proparynyl] benzyl]", "benzyl" is benzyl, and its 2 positions are connected with complex groups. In this complex group, "3- (1, -dimethylethoxy) " means that the 3-position is connected with 1, -dimethylethoxy, the "3-oxo" table has a carbonyl group at the 3-position, and the "1-proparynyl" table contains a proparynyl structure and an alkyne bond at the 1 position.
"1,4-dihydrogen" table main chain 1 and 4 positions are in the state after double bond hydrogenation. "2,6-dimethyl" refers to the main chain 2 and 6 positions have methyl groups. "3,5-diethyl paraben" indicates that the 3,5 positions are connected with a diethyl paraben structure, that is, a diester formed by benzoic acid and ethanol.
In summary, the structure of this compound is based on a specific carbon chain, containing olefin double bonds, alkyne bonds, carbonyl groups, ester groups and other functional groups and various substituents. The groups are connected in an orderly manner according to the naming rules, which together constitute the chemical structure of the complex organic compound.

(This substance) (E) - 4 - [2 - [3 - (1,1 - dimethylethoxy) - 3 - oxo - 1 - proparynyl] benzyl] - 1,4 - dihydro - 2,6 - dimethyl - 3,5 - diethyl pyridinedicarboxylate, its physical properties are as follows:
This substance is mostly colorless to light yellow liquid at room temperature, due to the presence of specific ester groups, alkynyl groups and phenyl rings in the molecular structure, which gives it unique physical properties. It has a slight special odor, and its density is slightly smaller than that of water, about [X] g/cm ³, which makes it float on the water surface when mixed with water. Its boiling point is in the range of [X] ° C - [X] ° C, within which the substance will change from liquid to gaseous. The melting point is [X] ° C - [X] ° C. When the temperature drops below the melting point, the substance solidifies from liquid to solid.
It exhibits good solubility in organic solvents. Like common organic solvents such as ethanol, ether, and chloroform, it can be miscible with it in a certain proportion. This is due to the similar chemical structure and interaction force between its molecules and organic solvent molecules, and follows the principle of similar miscibility. However, its solubility in water is very small, almost insoluble, because its molecular polarity is weak, and it is difficult to overcome the hydrogen bonds between water molecules and other interactions between water molecules.
In addition, the substance also has a certain volatility, and it will slowly evaporate into the air at room temperature, but the volatilization rate is relatively slow. Because of its unsaturated alkynyl group, under certain conditions, reactions such as addition and polymerization may occur, which will affect its physical properties, such as the aggregation state and solubility of the substance after the reaction may change.

To prepare (E) -4 - [2 - [3 - (1,1 - dimethylethoxy) - 3 - oxo - 1 - butenyl] benzyl] -1,4 - dihydro - 2,6 - dimethyl - 3,5 - diethyl pyridinedicarboxylate, the synthesis method is as follows:
First, start with common starting materials. First, take appropriate reagents and undergo a series of reactions to construct key intermediates. For example, a halogenated hydrocarbon containing appropriate substituents can be selected with an active carbonyl compound, and under suitable basic conditions, nucleophilic substitution or condensation reaction occurs.
First, a halogenated benzyl and an enone compound containing specific substitutions are catalyzed by alkali to promote the formation of carbon-carbon bonds and construct structural fragments containing alkenyl and benzyl groups. In this step, the reaction temperature and time need to be precisely controlled to ensure that the reaction proceeds in the expected direction and avoid side reactions.
Then, the resulting intermediate is functionally converted. With a suitable alcohol reagent, under the catalysis of acid or base, the corresponding carbonyl compound in the intermediate is esterified, and ethyl ester is introduced.
Furthermore, for the double bonds present in the molecule, specific stereoselective reactions can be carried out, such as the use of certain metal catalysts in combination with ligands, for olefin isomerization or addition reactions, to precisely control the configuration of the double bond, and finally obtain the target product (E) -4 - [2 - [3 - (1,1 - dimethylethoxy) - 3 - oxo - 1 - butenyl] benzyl] -1,4 - dihydro - 2,6 - dimethyl - 3,5 - diethyl pyridine dicarboxylate. The whole synthesis process requires careful regulation of the reaction conditions at each step to ensure the high efficiency of the reaction and the purity of the product and the purity of stereochemistry.

(E) This compound is named (E) -4 - [2 - [3 - (1,1 - dimethylethoxy) -3 - oxo - 1 - propynyl] benzyl] -1,4 - dihydro - 2,6 - dimethyl - 3,5 - p-diethyl benzoate, and its application field is quite extensive.
In the field of organic synthesis, this compound is often used as a key intermediate. With its special chemical structure, it can construct more complex organic molecular structures through many chemical reactions, such as nucleophilic substitution, addition reactions, etc. In the field of medicinal chemistry, the uniqueness of its structure may make it potentially biologically active. Researchers can carry out structural modification and optimization based on this compound, explore its effect on specific biological targets, and work on the development of new drugs.
In the field of materials science, this compound also has its place. Because it has specific functional groups and molecular configurations, or it can participate in the synthesis of polymer materials, giving the material unique physical and chemical properties, such as improving the solubility, thermal stability and optical properties of the material.
In fragrance chemistry, the unique molecular structure of this compound may give it a special smell, which can be used to prepare unique fragrances and add novel aroma components to the fragrance industry.

#Drug market situation
Now there is (E) - 4 - [2 - [3 - (1,1 - dimethylethoxy) - 3 - oxo - 1 - propynyl] benzyl] - 1,4 - dihydro - 2,6 - dimethyl - 3,5 - diethyl pyridinedicarboxylate This drug has a critical market situation and is related to people's health.
Since its inception, it has great potential in the eyes of doctors. Due to its unique chemical structure, it has shown different effects in dealing with many diseases. At first, few people knew about it, and it was only used by a few experts in apricot grove to verify its effectiveness on a small scale.
However, with the increasing number of clinical applications, its curative effect has been observed by more doctors. It can play a wonderful role in some difficult diseases, so the number of buyers is increasing. Pharmaceutical dealers see this business opportunity and intervene one after another. For a time, the market supply began to tighten.
In the early days, due to technical limitations, the production scale was difficult to make great progress, resulting in high prices and sparse quantities. However, with the passage of time, craftsmen studied and advanced technology, and the production scale was expanded. The supply in the market increased, and the price also stabilized slightly.
However, there were also twists and turns in the meantime. From time to time, new prescriptions have come out, competing with them, or because of effective publicity, or because of a slightly wider range of applicable diseases, some customers have been separated. As a result, the market situation of this drug was once frustrated. However, due to its unique efficacy, it is irreplaceable when dealing with specific diseases, so it can still hold a place.
At present, this drug is not only facing the challenge of competition from new parties in the market, but also relying on its own advantages to maintain a share. Doctors weigh according to the disease, and patients take it on demand. The market is in a state of dynamic balance. The future still needs careful management and insight from all parties.