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What is the chemical structure of Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydrpyridine-3-5-dicarboxylate?
This is a question about the chemical structure of the substance "Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate". The name of this substance is long and complicated, and it is analyzed according to the naming rules of organic chemistry.
"Dimethyl" means that there are two methyl groups, which are simple alkyl groups and are often connected to the main chain of molecules. "2,6-dimethyl" indicates that there is a methyl group at a specific position in the main chain, that is, at the 2nd and 6th positions. "4 (3-nitrophenyl) " means that a 3-nitrophenyl group is connected at the 4th position, and there is a nitro substitution at the 3rd position of this phenyl group. " 1,4-Dihydropyridine "reveals that the main chain is a dihydropyridine structure, which is formed by hydrogenation at the 1st and 4th positions of the pyridine ring." 3,5-dicarboxylate "indicates the existence of two carboxylic acid ester groups at the 3rd and 5th positions.
In general, the structure of this substance is based on dihydropyridine as the core, with methyl groups at the 2nd and 6th positions, 3-nitrophenyl groups at the 4th position, and carboxylic acid ester groups at the 3rd and 5th positions. Its structure is complex, and each group affects each other, which determines the chemical and physical properties of the substance. It may have unique uses in organic synthesis, medicinal chemistry and other fields.
What are the main uses of Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydrpyridine-3-5-dicarboxylate?
Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate is the name of a chemical substance. It is widely used in the field of medicine and is often used as a key intermediate for cardiovascular drugs. The specific regulatory effect of 1,4-dihydropyridine compounds on calcium ions can help regulate the contraction of the smooth muscles of the heart and blood vessels, and then be used in the treatment of cardiovascular diseases such as hypertension and angina pectoris.
In the field of organic synthesis, this substance can act as an important synthetic building block due to its unique chemical structure. Chemists can perform various chemical reactions on it, such as substitution reactions, oxidation reactions, etc., to prepare more complex and diverse organic compounds, providing key basic raw materials for new drug research and development, materials science and many other fields.
In addition, in chemical research, it is also an important research object. Scientists can further clarify the properties of 1,4-dihydropyridine compounds through in-depth exploration of their reaction mechanisms and physicochemical properties, thereby promoting the development of organic chemistry, medicinal chemistry and other disciplines, and laying a solid foundation for the development of more efficient and safe drugs and functional materials.
What is the production method of Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,1 4-dihydrpyridine-3-5-dicarboxylate?
The method of preparing dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate is an important process in the field of organic synthesis. Its common preparation route follows the classic Hantzsch reaction mechanism.
In the past, this compound was often prepared from methyl acetoacetate, 3-nitrobenzaldehyde and ammonia source. First, 3-nitrobenzaldehyde and methyl acetoacetate are condensed under specific conditions. This process requires careful regulation of the reaction temperature, solvent and catalyst. Usually, ethanol is used as a solvent, and an appropriate amount of organic acid is used as a catalyst. Under mild heating, the condensation reaction between the two occurs slowly to form a key reaction intermediate.
Then, an ammonia source, such as ammonium acetate, is added to further react with the intermediate. In this step, the amount of ammonia source and the reaction time have a great impact on the yield of the product. Under appropriate reaction conditions, after multiple complex reaction steps, molecular rearrangement, cyclization, etc., the target product is dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate.
With the evolution of technology, there are also improved methods. If microwave radiation technology is used, the reaction process can be significantly accelerated, the reaction time can be shortened, and the purity and yield of the product can be improved. Microwave radiation can efficiently stimulate molecular activity and promote the reaction to proceed more efficiently, providing a more convenient and efficient way for the preparation of the compound.
In addition, ionic liquids are used as the reaction medium. The unique physical and chemical properties of ionic liquids can optimize the reaction environment and improve the reaction selectivity and yield. This is also a promising preparation method.
Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1, 4-dihydrpyridine-3-5-dicarboxylate What are the precautions during storage and transportation?
Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate requires careful attention during storage and transportation.
This material is delicate and afraid of light and heat. If exposed to strong light or high temperature, its molecular structure may be damaged, resulting in quality deterioration. Therefore, when storing, it is advisable to choose a cool and dark place, and the temperature should be controlled within a suitable range, and the temperature must not exceed the limit.
Furthermore, it is quite sensitive to humidity. The environment is too humid, or it absorbs moisture, causing deliquescence and other conditions, which will damage the quality. It is necessary to keep the storage place dry, and a desiccant can be placed around to reduce the influence of humidity.
During transportation, it is important to be stable. This product is not resistant to bumps and vibrations, violent shaking or damage to the packaging, and then expose the material. The packaging should be solid and reliable, and it should be properly fixed in the transportation vehicle to prevent its displacement and collision.
At the same time, due to its unique chemical properties, it should not be mixed with other substances. Especially avoid coexisting with strong oxidizing agents, strong acids and alkalis, so as not to trigger chemical reactions and cause danger. Transport personnel should also be familiar with the characteristics of this material and be able to deal with it properly in case of emergencies.
In conclusion, the storage and transportation of dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate requires attention to temperature and humidity, stability and isolation to ensure its quality and safety.
What is the market outlook for Dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydrpyridine-3-5-dicarboxylate?
Today, there is a thing called dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate. The prospect of this product in the market is quite fascinating to explore.
Looking at the current field of pharmaceutical chemistry, such compounds are often involved in the research and development of cardiovascular drugs. Today, cardiovascular diseases are raging, and there are many patients. Doctors are struggling to find good medicines to treat them, and compounds containing this structure may have special effects in regulating cardiovascular function. Therefore, in pharmacies, their demand may be on the rise.
Furthermore, in the process of scientific research, the characteristics and efficacy of new compounds are not studied. This dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate, or contains unknown potential, can be used as a new target for scientific research. If researchers want to explore its details, they must have something to ask for. The market is here, and there is hope for expansion.
Of course, the market prospect is not smooth sailing. If the preparation method is complicated and abnormal, the cost will be high. If the cost is high, the selling price will be difficult to get close to the people, which will hinder marketing activities. And competing products of the same kind may have been preconceived and have occupied a place. To get a share of the market, there must be something outstanding, such as better curative effect and fewer side effects.
In summary, dimethyl-2,6-dimethyl-4 (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate, in the pharmaceutical and chemical market, opportunities and challenges coexist. If its characteristics can be well used to overcome the preparation problems and improve the quality, the prospect may be optimistic; conversely, it may be trapped in various obstacles and difficult to develop grand plans.