Diethyl 5-methylpyridine-2,3-dicarboxylate

Diethyl 5-methylpyridine-2,3-dicarboxylic acid ester, this is an organic compound. It has specific chemical properties.
Looking at its physical properties, it is mostly liquid or solid under normal conditions, with a certain melting point and boiling point, depending on specific conditions. In terms of solubility, it can be soluble in organic solvents such as ethanol and ether, but its solubility in water is limited.
Its chemical properties are unique due to the presence of ester groups and pyridine rings. Ester groups can undergo hydrolysis reactions. Under acidic or alkaline conditions, hydrolysis is accelerated, and bases act as catalysts to promote the reaction. Pyridine rings are basic and can react with acids to form salts. Because the nitrogen atom on the pyridine ring has lone pair electrons, it can accept protons. In addition, due to the presence of methyl groups, the methyl groups can undergo substitution reactions under suitable conditions, such as halogenation reactions, and specific reagents and conditions can cause methyl hydrogen to be replaced by halogen atoms. And because of its conjugation system, the pyridine ring can participate in electrophilic substitution reactions and introduce substituents at appropriate positions, and the reactivity and selectivity are affected by the substituents on the ring.

In the field of organic synthesis, this compound is often used as a key intermediate. Because its molecular structure contains specific functional groups, it can be prepared by a variety of chemical reactions. For example, through the hydrolysis reaction of ester groups, it can be converted into corresponding carboxylic acids; or by transesterification reaction, different alkyl groups are introduced to expand the variety of compounds, providing a basis for the creation of new organic materials, drug lead compounds, etc.
In the field of medicinal chemistry, diethyl-5-methylpyridine-2,3-dicarboxylate may have potential medicinal value. Its structure can be modified and modified to meet the needs of specific biological targets. Or as a starting material for building a complex drug molecular skeleton, through subsequent reactions, the product is endowed with specific pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor and other activities, paving the way for the development of new drugs.
It is also useful in materials science. Through specific polymerization reactions or modification methods, it can be introduced into polymer materials to change the physical and chemical properties of the materials. For example, to improve the solubility, thermal stability, optical properties of materials, etc., to prepare functional materials suitable for specific fields, such as photoelectric materials, polymer catalyst supports, etc.
In summary, diethyl-5-methylpyridine-2,3-dicarboxylate has shown important uses in many fields such as organic synthesis, pharmaceutical chemistry, and materials science, and has broad application prospects.

To prepare diethyl-5-methylpyridine-2,3-dicarboxylic acid ester, the following ancient method can be used.
First take an appropriate amount of 5-methylpyridine-2,3-dicarboxylic acid and place it in a clean reactor. Using anhydrous ethanol as a solvent, slowly pour it into the kettle, so that 5-methylpyridine-2,3-dicarboxylic acid is fully dissolved in it. Then, add an appropriate amount of concentrated sulfuric acid as a catalyst. Concentrated sulfuric acid has a catalytic effect and can promote the reaction.
Close the reactor and place it on the heating device to slowly heat up. Control the temperature to a suitable range, usually between 80 and 100 degrees Celsius. Temperature control is very critical. If it is too high, side reactions will increase, and if it is too low, the reaction rate will be delayed.
When reacting, continue to stir to mix the reactants evenly, so that the reaction is sufficient. After several hours of reaction, the reaction solution gradually changes as expected.
When the reaction is complete, cool the reaction solution. Then neutralize the sulfuric acid in an appropriate amount of saturated sodium carbonate solution until the solution is weakly alkaline. This step can remove excess sulfuric acid and prevent the product from decomposing in an acidic environment.
Separate the liquid and take the organic phase. The organic phase is washed several times with distilled water to remove impurities. After washing, the organic phase is dried with anhydrous magnesium sulfate to remove residual moisture.
Finally, a reduced pressure distillation method is performed to collect the fraction with a specific boiling point range, which is diethyl-5-methylpyridine-2,3-dicarboxylate. After these steps, a pure target product can be obtained.

I think what you are asking is about the market price of "Diethyl 5 - methylpyridine - 2,3 - dicarboxylate". However, the price of this chemical often changes for a variety of reasons.
First, the trend of supply and demand, if the demand for this product is strong, but the supply is scarce, its price will rise; on the contrary, if the supply is abundant and the demand is weak, the price will be depressed. Second, the preparation is difficult and simple. If the preparation requires complicated methods and rare raw materials, the cost will be high, and the price will follow. If the preparation is easier and the cost is low, the price will not be high. Third, the competition in the market is intense, or the price will be reduced in order to compete for the market; if the competition is slow, the price may rise steadily.
And because I don't know the situation of this thing in "Tiangong Kaiwu", according to common sense, if you want to know its exact price, you can visit the market of chemical materials, consult the merchants specializing in this industry, or check the information platform of chemical product prices to get a near-real price. Don't just rely on assumptions, it is appropriate to take market conditions as the basis.

When storing and transporting diethyl-5-methylpyridine-2,3-dicarboxylate, many matters must be paid attention to.
The properties of this compound are quite critical. It is sensitive to heat or high temperature, and it is easy to decompose or initiate reactions. Therefore, the temperature of the storage place should be low and stable, and it should be protected from direct sunlight, because light can also promote its change. In addition, it may have certain chemical activity and come into contact with or react with certain substances, so it must be stored separately from strong oxidants, strong acids, strong bases and other substances, and must not be mixed.
For transportation, the packaging must be solid and reliable. Special containers are required to ensure good sealing to prevent leakage. During transportation, avoid violent vibrations and collisions to avoid package damage. If this compound is toxic or irritating, transport personnel should be equipped with protective equipment, such as protective clothing, gloves, gas masks, etc., for safety. At the same time, the transport vehicle should be well ventilated to prevent the accumulation of volatile gas in the vehicle.
In addition, whether it is storage or transportation, the relevant information should be clearly recorded, including quantity, batch, storage or transportation conditions, etc., for future inspection. Only with such caution can the safety and stability of diethyl-5-methylpyridine-2,3-dicarboxylate during storage and transportation be ensured.