butyl pyridine-3-carboxylate

Butylpyridine-3-carboxylate has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. With its unique chemical structure, it can participate in various chemical reactions, and then build various complex organic compounds.
For example, in pharmaceutical chemistry, it can be used as a starting material or an important structural fragment for the synthesis of specific drug molecules. Drug developers can chemically modify and derive butylpyridine-3-carboxylate, or create drugs with novel pharmacological activities, providing new opportunities for the treatment of various diseases.
In the field of materials science, butylpyridine-3-carboxylate also has outstanding performance. It can be used to prepare some functional materials, such as polymers with special properties. By introducing it into the polymer structure, it can endow the material with unique solubility, thermal stability or optical properties, etc., to meet the needs of different fields for special properties of the material.
In addition, in the fragrance industry, it may be used as an ingredient for the preparation of fragrances due to its special odor and chemical properties, adding a different aroma level to fragrance products and enriching fragrance categories.
Furthermore, in scientific research experiments, butylpyridine-3-carboxylate is used as a common reagent to provide chemists with assistance for exploring new reaction paths and studying reaction mechanisms, and to promote the continuous development of organic chemistry theory and practice.

Butylpyridine-3-carboxylic acid ester is one of the organic compounds. Its physical properties are crucial and related to many applications of this substance.
First of all, butylpyridine-3-carboxylic acid ester is often liquid, with clear texture and specific fluidity. This property is convenient for transfer and operation in many chemical reactions or industrial processes.
Second, the boiling point of this compound is moderate. The appropriate boiling point makes it easier to control the temperature conditions during distillation, separation and other operations, so as to achieve effective separation from other substances and ensure the purity of the product.
Furthermore, solubility is also an important property. Butylpyridine-3-carboxylate exhibits good solubility in organic solvents, such as common ethanol, ether and other organic solvents, which can be miscible with it. This solubility property is conducive to its participation in organic synthesis reactions as a solvent, or as a carrier in the field of drug research and development, assisting the dissolution and dispersion of active ingredients.
In addition, density is also one of its physical properties. The specific density gives it a unique layering property in mixtures, which plays a key role in some processes that require separation through density differences.
Its appearance may have a weak color, but it is generally more transparent. This appearance property is convenient for observation and monitoring of its state in practical applications.
In summary, the physical properties of butylpyridine-3-carboxylic acid esters, including liquid properties, moderate boiling point, good solubility and specific density, are of great significance in organic synthesis, industrial production and related scientific research fields, laying the foundation for their wide application.

Butylpyridine-3-carboxylic acid ester, this is an organic compound. Its chemical stability depends on various factors and depends on the environment and conditions.
Under normal conditions, butylpyridine-3-carboxylic acid ester has certain chemical stability. In its structure, the pyridine ring is connected to the carboxyl ester group. The pyridine ring is an aromatic structure and has certain stability due to the conjugation effect. It can reduce the overall energy of the molecule and is not easy to react easily. Although the ester group formed by carboxyl and butyl is slightly more active than the pyridine ring, it is also relatively stable under mild conditions.
In case of specific chemical reagents, the stability of butylpyridine-3-carboxylate may be affected. In case of strong acid and alkali, ester groups may undergo hydrolysis. In acidic media, protons will attack the carbonyl carbon of the ester group, causing it to hydrolyze to form pyridine-3-carboxylic acid and butanol; under basic conditions, hydroxide ions nucleophilic attack carbonyl carbon, and the hydrolysis rate is faster. The products are pyridine-3-carboxylate and butanol.
Temperature also plays a role in its stability. High temperature will increase the thermal motion energy of the molecule, increase the reactivity, or cause the decomposition of butylpyridine-3-carboxylate or other chemical reactions. Light or the presence of a specific catalyst may also trigger the reaction of the compound and change its chemical stability.
In summary, the chemical stability of butylpyridine-3-carboxylate is not absolute, and it can remain relatively stable under mild and common conditions. However, when the specific chemical environment, temperature, light and other factors change, its stability may be damaged and corresponding chemical reactions occur.

The method of preparing butylpyridine-3-carboxylic acid ester has followed the following methods in the past.
First, pyridine-3-carboxylic acid and n-butanol are used as materials, and acid is used as a catalyst to carry out the esterification reaction. Among them, sulfuric acid and p-toluenesulfonic acid are both commonly used acid catalysts. During the reaction, pyridine-3-carboxylic acid and n-butanol need to be mixed in a suitable ratio in the reaction vessel, an appropriate amount of catalyst is added, and heating is refluxed. During the process, the control of temperature is quite critical, generally maintained near the boiling point of n-butanol, so that the reaction can proceed steadily. After the reaction is completed, pure butylpyridine-3-carboxylic acid ester can be obtained through neutralization, liquid separation, distillation and other operations. The advantage of this approach is that the raw materials are easy to find and the reaction principle is clear; however, the drawbacks are also obvious, such as the risk of corrosion of the catalyst to the equipment, and the subsequent processing is complicated.
Second, pyridine-3-carboxylic acid derivatives are reacted with butylating reagents. Such as pyridine-3-carboxylic acid chloride and n-butanol, in the presence of bases, can be formed into butylpyridine-3-carboxylic acid esters. Bases are commonly used in triethylamine and pyridine, which act as acid binding and promote the reaction to move right. Compared with the former, the conditions of this reaction are slightly milder and the yield is better. However, the preparation of pyridine-3-carboxylic acid chloride requires additional steps, and its properties are active, so it needs to be carefully preserved and handled.
Third, it is prepared by the coupling reaction catalyzed by transition metals. For example, with the help of transition metal catalysts and ligands such as palladium, pyridine-3-borate and halobutane, the carbon-oxygen bond is constructed to obtain the target product. This method has the advantages of good selectivity and mild conditions. However, the transition metal catalyst is expensive, and the reaction system is relatively complex, and the reaction conditions are strictly controlled. The cost consideration in actual production is quite heavy.

However, the price range of yl pyridine-3-carboxylate in the market is difficult to determine. Cover this compound, or due to purity, source, supply and demand in the market, its price fluctuations are unstable.
Looking at the price of various chemical raw materials, the price of pure is high, and the price of miscellaneous is average. If this is the case, but the purity of yl pyridine-3-carboxylate is very high, and it is used in important places such as fine chemical industry and pharmaceutical development, its price must be high. On the contrary, if the purity is slightly inferior, it is only for general industrial use, and the price is slightly cheaper.
Also, the place where this compound is produced is different, and it is also related to the price. The place of origin is close to the city, the freight is provincial, and the price is close to the people; if the place of origin is far away, the freight will increase, and the price will also increase.
Furthermore, the supply and demand of the city is the key to the price. If there are many applicants, if there are few suppliers, the price will be raised; if the demand is rare, if the supplier is sufficient, the price will be depressed.
To sum up, if you want to know the exact price of yl pyridine-3-carboxylate, you need to carefully observe its purity, source, and the supply and demand situation of the market. Or consult a chemical raw material supplier, or check a professional price information platform, you can get a more accurate price. However, roughly speaking, the price per kilogram ranges from tens to hundreds of yuan, but the actual situation varies according to the specific situation.