Bistrifluoromethylsulfonylaminochloropyridine

Bistrifluoromethylsulfonylaminochloropyridine, the Chinese name is bis (trifluoromethylsulfonyl) aminochloropyridine, which is widely used in the field of agrochemistry and medicine.
In the field of agrochemistry, it is a key intermediate in the synthesis of pesticides. Due to its unique chemical structure and properties, it can endow pesticides with characteristics such as high efficiency, low toxicity, and broad spectrum. For example, pesticides made from it are effective on pests such as Lepidoptera and Homoptera. After pests come into contact with or ingest pesticides containing this ingredient, they can interfere with the nervous system or physiological and metabolic processes and cause their death. And the pesticide has good environmental compatibility, fast degradation, and little residue, which meets the requirements of modern green agriculture for pesticides. In terms of fungicides, this synthetic product can effectively prevent and control a variety of crop fungal diseases. The mechanism of action is to inhibit the cell wall synthesis of pathogens or interfere with energy metabolism, and protect the healthy growth of crops.
In the field of medicine, it is an important raw material for the synthesis of specific drugs. Because of its structure, it is conducive to the design and modification of drug molecules, and can improve drug activity, selectivity and bioavailability. For example, in the development of anti-tumor drugs, the drug molecules constructed based on this can precisely act on tumor cell targets, inhibit tumor cell proliferation, induce apoptosis, and reduce damage to normal cells, improving therapeutic effect and safety. In terms of antiviral drugs, drugs containing this structure can be rationally designed to bind to key viral proteins, block the process of viral replication and transmission, and provide new directions and effective means for antiviral therapy.

One method is to take a specific pyridine substrate and replace it with chlorine. In this step, a suitable chlorination agent, such as phosphorus oxychloride, needs to be selected. In the appropriate temperature and solvent environment, the hydrogen on the pyridine ring is replaced by chlorine atoms to obtain chloropyridine intermediates.
Second, the chloropyridine intermediate is reacted with bis (trifluoromethylsulfonyl) imide reagent. This reaction may require the help of a catalyst, such as some metal salts, to promote the bonding of the two to obtain Bistrifluoromethylsulfonylaminochloropyridine. During the reaction, the choice of solvent is also critical, and a polar aprotic solvent is required to facilitate the reaction. < Br >
Another method is to derive the active group from bis (trifluoromethylsulfonyl) imide, and then react with the chloropyridine precursor. This active group may be activated by specific reagents, such as after reacting with bases, it is easier to bind to chloropyridine. During the reaction process, the reaction conditions, such as temperature, time, and the proportion of reactants, need to be strictly controlled to achieve a higher yield.
In addition, there is also a method of gradually constructing pyridine rings, first synthesizing the amino fragment containing bis (trifluoromethylsulfonyl), and then closing the ring with the chlorine-containing fragment under appropriate conditions to form a pyridine ring, and finally obtaining the target product. However, this method is slightly more complicated and requires higher control of the reaction conditions. All kinds of synthetic methods have their own advantages and disadvantages, and craftsmen often choose them based on factors such as raw material availability, cost, yield and product purity.

Bistrifluoromethylsulfonylaminochloropyridine is one of the organic compounds. Its physical and chemical properties are particularly important and affect many application fields.
In terms of its physical properties, under normal temperature and pressure, or in a solid state, this is due to the interaction and structure between molecules. Its melting point and boiling point are also key physical properties. The melting point is related to the temperature required to change from the solid state to the liquid state, which is affected by factors such as intermolecular forces and crystal structure. The boiling point is related to the critical temperature of the liquid state to the gas state, reflecting the energy required for the molecule to break free from the liquid phase.
Looking at its chemical properties, the compound contains chlorine atoms, pyridine rings and specific sulfur-containing fluorine groups. The chlorine atom has certain reactivity and can participate in the nucleophilic substitution reaction. The pyridine ring is an aromatic heterocycle, which can undergo electrophilic substitution reaction, and the existence of nitrogen atoms makes the electron cloud distribution of the pyridine ring unique, which affects the reactivity and selectivity. The amino part of bis (trifluoromethanesulfonyl), due to the strong electron absorption of trifluoromethyl, gives the group a unique electronic effect, which can affect the reactivity and stability of the whole molecule. This compound can be used as a key intermediate in the field of organic synthesis. Because of its various activity check points, it can construct more complex organic molecular structures through different reaction paths, and has potential applications in materials science, medicinal chemistry and other fields.

When "Tiangong Kaiwu" was written, there was no "Bistrifluoromethylsulfonylaminochloropyridine". This is a fine chemical synthesized by modern chemistry, and it is difficult for me to tell you its market price range in the format of ancient proverbs. However, in today's world, the price of this chemical fluctuates due to many factors such as purity, origin, market supply and demand. For details, you should consult chemical raw material market merchants, chemical product trading platforms or related industry people, who may be able to tell you the approximate price according to the current facts.

Bistrifluoromethylsulfonylaminochloropyridine, chemical things are also. However, as far as I know, the exact manufacturer is not detailed in the books. In today's world, the chemical industry is prosperous, and there are many producers of such chemicals.
There are factories that cover the world's chemical industry, specializing in fine scholars, or involved in the manufacture of this product. However, if you want to know the details, you need to widely seek the chemical catalog and industry information. Or there are large factories with strong resources and advanced research and development, which can produce this chemical; or there are specialized small factories, which have unique ingenuity in the sub-field and get involved in it.
Today's chemical information can be found on the Internet, chemical forums, professional exhibitions, etc. Although I have not obtained the actual evidence of the manufacturer of this product, if I want to know the details, I can visit it in detail, or I can get one or two of them. Hope to help you solve your doubts and help you explore the manufacturer.