Amino 3 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

amino-3-nitropyridine

    Specifications

    HS Code

    771624

    Chemical Formula C5H5N3O2
    Molar Mass 139.11 g/mol
    Appearance Yellow - solid
    Melting Point 165 - 167 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, acetone
    Pka Value For the amino group: around 9 - 10
    Isomerism Exists as a single structural isomer with the given connectivity
    Stability Stable under normal conditions, but can react with strong oxidizing agents

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    General Information
    Where to Buy amino-3-nitropyridine in China?
    As a trusted amino-3-nitropyridine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading amino-3-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of amino-3-nitropyridine?
    Amino-3-nitropyridine has a wide range of uses. It is a key traditional Chinese medicine in the field of medicine. With its unique chemical structure, it can interact with molecules in organisms to help develop new drugs and treat various diseases. For example, it has affinity for specific disease targets, can be used as the basis for drug active ingredients, or is an important building block for the synthesis of complex drug molecules.
    In the field of materials science, it is also indispensable. It is often a raw material for the preparation of materials with special properties. After chemical reactions, it can endow materials with novel electrical and optical properties. If it can participate in the synthesis of materials with specific electrical conductivity or photoluminescence properties, it is expected to be applied in electronic devices, optical displays, etc.
    In the field of pesticides, it also makes a difference. Or due to its structural characteristics, it has the effect of inhibiting or killing certain pests or pathogens, and can be used to develop new pesticides to ensure the healthy growth of crops and protect the smooth agricultural production.
    And in organic synthesis chemistry, amino-3-nitropyridine is a commonly used intermediate. With its amino and nitro groups, it can undergo various chemical reactions, introduce other functional groups, and construct more complex organic molecular structures, which contribute to the expansion of organic synthesis and promote the development of chemical synthesis.
    What are the physical properties of amino-3-nitropyridine?
    Amino-3-nitropyridine is one of the organic compounds. Its physical properties are unique, let me explain in detail for you.
    Under normal conditions, this substance is mostly in a solid state, but the specific form may vary slightly depending on the preparation conditions, or it is crystalline, crystal clear, or powder state, delicate and subtle.
    When it comes to color, amino-3-nitropyridine often appears light yellow to yellow, and its color is bright and eye-catching.
    Its melting point is also one of the important physical properties. Generally speaking, the melting point is within a certain range, which is crucial for the identification and purification of this substance. Due to the different purity of amino-3-nitropyridine, the melting point may be slightly different, so the purity can be judged according to the melting point.
    Furthermore, the solubility is also its significant physical properties. In common organic solvents, such as ethanol, acetone, etc., amino-3-nitropyridine has a certain solubility. However, in water, its solubility is relatively low. This difference in solubility provides many possibilities for its separation, purification and application in different chemical reaction systems.
    As for the density, although it varies depending on the precise measurement conditions, it is roughly within a certain range. This density data has important reference value in the chemical production, storage and transportation of this substance.
    In summary, the physical properties of amino-3-nitropyridine, from morphology, color, melting point, solubility to density, all have their own characteristics, which play a crucial role in chemical research and related industrial applications.
    What are amino-3-nitropyridine synthesis methods?
    There are various ways to synthesize amino-3-nitropyridine. One is to use pyridine as the starting material, introduce nitro groups into the pyridine ring through nitration reaction, and then convert the nitro groups into amino groups through reduction reaction. Specifically, in the nitration step, pyridine can be co-placed with mixed acids of nitric acid and sulfuric acid, and the reaction temperature and time can be controlled to make pyridine nitrate accurately at 3 positions to obtain 3-nitropyridine. Subsequently, suitable reducing agents, such as iron powder, zinc powder, etc., are selected to reduce 3-nitropyridine in an acidic medium to obtain the target product, amino-3-nitropyridine.
    The second method can be started from pyridine derivatives containing amino groups and nitro groups, and achieved by appropriate functional group conversion. For example, first prepare a pyridine derivative with a specific substituent, which contains functional groups that can be converted into amino groups and nitro groups, and then carry out the corresponding reactions in sequence to convert the functional groups into amino groups and nitro groups one by one, and finally synthesize amino-3-nitropyridine. However, this approach needs to be carefully studied for each step of the reaction conditions to ensure the selectivity and yield of the reaction.
    Another method can use the coupling reaction catalyzed by transition metals. The target molecule is formed by the coupling reaction of pyridine derivatives containing suitable leaving groups and reagents containing amino or nitro groups under the action of transition metal catalysts such as palladium catalysts. This method requires careful screening of catalysts, ligands and reaction solvents to achieve efficient and highly selective synthesis. All these synthesis methods have advantages and disadvantages. In practical application, the choice needs to be weighed according to many factors such as the availability of raw materials, the feasibility of reaction conditions, the purity and yield of the product.
    What amino-3-nitropyridine need to pay attention to when storing and transporting
    3-Amino-3-nitropyridine, when it is stored and transported, all kinds of matters must be paid attention to. This is a chemical substance, its nature is different, and if it is slightly careless, it may cause disaster.
    When it is stored, the first environment is heavy. It should be placed in a cool, dry and well-ventilated place, away from direct sunlight, to prevent decomposition by heat and cause danger. Temperature and humidity should also be carefully controlled to avoid deterioration. Furthermore, it must be separated from other substances, especially those with oxidation, reduction or acidic and alkaline substances, to avoid chemical reactions, damage its quality, or even cause violent reactions, endangering safety.
    When shipping, the packaging must be tight. A suitable container should be used to keep it stable and not damaged by vibration and collision. The transporter must also undergo professional training to be familiar with the properties of this object and know how to deal with it in case of emergency. Always check the complete damage of the package on the way. If there is any leakage, take proper measures quickly and do not slack off.
    In addition, whether it is stored or shipped, detailed records must be kept, recording the quantity, entry and exit time and condition. Everyone should also strictly abide by the relevant regulations and must not violate them. In this way, the safety of 3-amino-3-nitropyridine storage and transportation can be avoided.
    What is the market outlook for amino-3-nitropyridine?
    Amino-3-nitropyridine, that is, amino-3-nitropyridine, the market prospect of this product is related to many aspects.
    In today's field of chemical synthesis, many new materials and drug research and development, the demand for this product is growing. In the field of materials, due to its unique molecular structure, it can be used as a key intermediate for the preparation of polymer materials with special properties. These materials are widely used in electronics, optics and other industries, such as the manufacture of high-performance display screens, semiconductor materials, etc. Therefore, with the vigorous development of related industries, the demand for amino-3-nitropyridine is expected to increase.
    As for drug development, it is also of great value in the construction of specific drug molecular structures. The pharmaceutical industry continues to explore innovative drugs to deal with various diseases. The chemical synthesis path involved in amino-3-nitropyridine may provide opportunities for the creation of new drugs, so the potential demand in the pharmaceutical field is considerable.
    However, its market prospects are also constrained by many factors. First, the complexity of the production process is closely related to the cost. If the production process is cumbersome and costly, the product price is bound to remain high, or the market expansion is restricted. Second, regulations and policies are increasingly strict in the supervision of chemicals. If amino-3-nitropyridine does not meet the standards in terms of environmental protection and safety, the production and sales will be hindered. Third, the market competition situation should not be underestimated. The emergence of congeneric products or alternative products, or the diversion of market share.
    Overall, amino - 3 - nitropyridine is driven by emerging industries, and the market prospect contains opportunities. To fully exploit this opportunity, we need to deal with many challenges such as production, regulations, and competition, and open up a broader market space by optimizing production processes, complying with regulatory requirements, and enhancing product competitiveness.