8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

8+-+%E6%B0%AF+-+6+-%EF%BC%88%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%EF%BC%89%E5%92%AA%E5%94%91%E5%B9%B6%5B1%2C2+-+a%5D%E5%90%A1%E5%95%B6+-+2+-+%E7%BE%A7%E9%85%B8%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E6%98%AF%E4%BB%80%E4%B9%88%3F this is a garbled character, I cannot accurately identify and understand its exact meaning. You can re-state the question clearly and accurately, so that I can answer you in the classical Chinese format of "Tiangong Kaiwu" as required.

To obtain 8-bromo-6- (triethylmethyl) quinoline [1,2-a] and to its 2-carboxyl group, the following methods can be used:
First, the corresponding quinoline derivative is used as the beginning, and bromine atoms are introduced by halogenation reaction. In a suitable solvent, such as dichloromethane, brominating reagents, such as N-bromosuccinimide (NBS), in the presence of an initiator such as benzoyl peroxide, temperature-controlled reaction, using electrophilic substitution mechanism, the bromine atoms fall precisely in the predetermined position to obtain bromine-containing intermediates. Subsequently, through a specific nucleophilic substitution or condensation reaction, triethyl groups are connected.
Second, the quinoline mother core containing triethyl methyl is first constructed, and then brominated. With suitable raw materials, such as aniline and corresponding carbonyl compounds, the quinoline ring is reacted in multiple steps, and triethyl methyl is introduced. Then select suitable bromination conditions, such as liquid bromine and catalyst combination, to achieve the introduction of bromine atoms at the target check point.
As for the introduction of carboxyl groups to the 2-position of the product, the Grignard reagent method can be used. First, the product and magnesium chips are prepared into Grignard reagent in anhydrous ether and other solvents, and then carbon dioxide is introduced, and the 2-carboxyl group product can be obtained by hydrolysis.
Or by nitrile hydrolysis, the cyano group is first introduced into the 2-position of the product, such as through nucleophilic substitution to access the cyano group, and then catalyzed hydrolysis with acid or base to convert the cyano group to the carboxyl group, thereby achieving the synthesis of 8-bromo-6- (triethylmethyl) quinoline [1,2-a] and 2-carboxyl.

"Tiangong Kaiwu" says: "The physicality of 8 + -alkane-6- (triethyl) octano [1,2-a] to its -2-carboxylic acid is related to the characteristics of material composition and reaction. Among this compound, 8 + -alkane has a chain-like structure, and the length and arrangement of its carbon chains determine its basic physical properties, such as melting point and boiling point. Generally speaking, the longer the carbon chain, the stronger the intermolecular force, the higher the boiling point, and the solubility is also affected, which tends to show better solubility in non-polar solvents.
As for the -6- (triethyl) part, the introduction of ethyl groups changes the spatial structure of molecules and the distribution of electron clouds. The presence of multiple ethyl groups increases the volume and steric barrier of molecules, affecting the interaction between molecules. This structural adjustment may change the chemical activity of the compound. In some reactions, the steric barrier is large, and the reactivity may decrease, hindering the reagent from approaching the reaction check point.
The octano [1,2-a] structure endows the compound with unique rigidity and stability. The existence of this thick ring structure strengthens the stability of the molecule and also has a significant impact on its chemical properties. In chemical reactions, higher energy may be required to initiate the reaction due to its stable structure, or a special reaction path may be exhibited under specific conditions.
The last part of the -2-carboxylic acid, the presence of the carboxyl group (-COOH), imparts acidic properties to the compound. The carboxyl group can ionize hydrogen ions, making the compound have the general property of acid, and can neutralize with bases to generate corresponding salts and water. And the carboxyl group can participate in various organic reactions such as esterification reaction, which greatly enriches the chemical properties of the compound. In summary, the physicochemical properties of 8 + -alkane-6- (triethyl) octano [1,2-a] -2-carboxylic acids exhibit unique properties due to the synergistic structure of each part.

I have heard your inquiry about the market price of triethylaminoindole and its derivatives. The price of these two in the market is difficult to determine, and the price often changes due to various factors.
As far as triethylaminoindole is concerned, its price is related to the quality. If it is high quality, pure and less heterogeneous, the price must be high; the quality is the opposite. And its preparation process also affects, the difficulty of preparation, the price of materials used, all lead to fluctuations in price. Furthermore, market supply and demand are also the main reasons. If the demand is strong and the supply is small, the price will rise; if the supply exceeds the demand, the price will be depressed. < Br >
As for its derivative 2-carboxyl-1,2-a indole, the situation is similar. Quality, process, supply and demand all affect its price. And this derivative may be difficult to synthesize, the materials used are rare, and the price may be higher than that of triethylaminoindole.
If you want to know its price, you should visit various pharmaceutical merchants, chemical raw material houses, or check industry information and trading platforms. Only then can you get real-time prices in the market as evidence for business planning or research.

I look at your words about the storage conditions of octanitrate-cyanogen-hexa (triethylmethyl) pyridino [1,2-a] pyridino-2-carboxylic acid. These things are related to chemistry, which is very important, and may cause harm.
Octanitrate-cyanogen-hexa (triethylmethyl) pyridino [1,2-a] pyridino-2-carboxylic acid should be stored in a cool, dry and well-ventilated place. This is due to its nature or fear of heat and moisture. If it is in a warm and humid place, it may cause qualitative change, damage its effectiveness, or even be dangerous.
And must be kept away from fire and heat sources. Nitrate materials are mostly flammable and explosive. When exposed to open flames and hot topics, they are easy to cause violent reactions and endanger the safety of the surroundings.
should also be stored separately from oxidants and edible chemicals, and must not be mixed. Different chemicals interact with each other or cause unpredictable changes, which can lead to disasters.
Storage places should be equipped with suitable materials to contain leaks. In case of leakage, they can be dealt with in time to prevent their spread and cause greater harm.
When handling, be sure to unload lightly to prevent damage to packaging and containers. If the packaging of this medicine is damaged, it will not only affect its quality, but the leakage may also pollute the environment and harm humans and animals.
In short, the storage of octanitrate-cyanogen-hexa (triethylmethyl) pyridine-2-carboxylic acid needs to be treated with caution, and the above conditions should be strictly observed to ensure safety.