7-Methylimidazo[1,2-a]pyridine-3-carbaldehyde

7-Methylimidazolo [1,2-a] pyridine-3-formaldehyde, which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to help synthesize many biologically active compounds. For example, when creating new antimalarial drugs, their structural properties can be combined with specific targets in the malaria parasite. After modification and derivatization, it is expected to develop new antimalarial drugs with good efficacy.
In the field of materials science, because the compound has specific electronic structure and optical properties, or can participate in the preparation of organic optoelectronic materials. Like in the exploration of organic Light Emitting Diode (OLED) materials, it can become an important component in building the structure of the luminous layer, endowing the material with unique luminous properties and improving the OLED display effect.
In the research and development of pesticides, with its special action mechanism on some biological enzymes, it can be used as a lead compound for structural optimization. After modification, it may become a new type of pesticide with high efficiency, low toxicity and environmental friendliness, which can be used to precisely control crop diseases and pests and ensure agricultural production.
In summary, 7-methylimidazolo [1,2-a] pyridine-3-formaldehyde has potential application value in the fields of medicine, materials, pesticides, etc., providing an important basis for many research and innovation.

The synthesis method of 7-methylimidazolo [1,2-a] pyridine-3-formaldehyde is not directly described in the classic "Tiangong Kaiwu", but it can follow the principle of chemistry and refer to the method of similar synthesis.
First, it can be started from the corresponding pyridine derivatives. First, take a suitable pyridine raw material, and introduce the 7-position methylation through a specific alkylation reaction. This alkylation step should be selected under mild conditions and an effective catalyst to prevent side reactions. Then, through cyclization, the structure of imidazolo [1,2-a] pyridine is constructed. When cyclization, the reaction temperature, duration and ratio of reactants need to be controlled to make the cyclization proceed smoothly. Finally, the aldehyde group is introduced at the 3 position by suitable oxidation or formylation means. This formylation process is essential for the selection of reagents and reaction environment, or the classic Vilsmeier-Haack reaction can be used, depending on the raw materials and conditions.
Second, the imidazole derivative can also be started. First, the imidazole is specially modified to have an activity check point connected to the pyridine ring. After condensation reaction, an imidazolo [1,2-a] pyridine skeleton is formed. During the process, attention is paid to the activity and selectivity of the reaction, and the reaction parameters are optimized. Subsequent to the previous method, methyl and aldehyde groups are introduced at appropriate stages to complete the synthesis of the target product. Every step of the reaction needs to be carefully monitored to ensure the purity and yield of the product. Although "Tiangong Kaiwu" does not involve this specific synthesis, today's chemistry and scientific methods can make this synthesis possible.

7-Methylimidazolo [1,2-a] pyridine-3-formaldehyde, the physical properties of this substance are related to its appearance, melting point, boiling point, solubility and other characteristics.
Looking at its appearance, under room temperature and pressure, it may be in a solid state, the color may be white to light yellow powder, or a crystalline solid, depending on its purity and preparation method.
As for the melting point, after many experiments, it is about a specific temperature range. This temperature range varies slightly due to the measurement environment and equipment accuracy, but it can be roughly framed around a certain value. This value is extremely beneficial for determining its purity and performing related chemical operations.
In terms of boiling point, under specific pressure conditions, the temperature when the substance reaches the boiling state is of great significance for its separation, purification and other process operations. Only by accurately knowing the boiling point can we reasonably plan distillation and other processes to obtain pure target products.
Solubility is also one of the important physical properties. In organic solvents, such as common ethanol and dichloromethane, the degree of solubility varies. In ethanol, according to the principle of similar miscibility, some functional groups interact with ethanol molecules to show a certain solubility; in dichloromethane, 7-methylimidazolo [1,2-a] pyridine-3-formaldehyde also exhibits unique solubility due to the polar and structural characteristics of dichloromethane. In water, due to the large proportion of hydrophobic groups in its molecular structure, its solubility is relatively poor.
In addition, the physical properties such as density and refractive index of the substance also play an important role in specific chemical analysis and chemical production processes, which can assist in the identification of substances and the monitoring of reaction progress.

7 - Methylimidazo [1,2 - a] pyridine - 3 - carbalaldehyde is an organic compound. It has an aldehyde group, so it has the typical chemical properties of an aldehyde. The aldehyde group can undergo oxidation reaction. Under the action of mild oxidizing agents such as Torun reagent (silver ammonia solution), a silver mirror reaction can occur to generate a bright silver mirror. This reaction can be used to identify the existence of aldehyde groups; in case of Feilin reagent, a brick red precipitation can be produced.
Its aldehyde group can also undergo reduction reaction. With hydrogen as a reducing agent, the aldehyde group can be reduced to an alcohol hydroxyl group and converted to 7 - Methylimidazo [1,2 - a] pyridine - 3 - methanol in the presence of suitable catalysts such as nickel.
At the same time, due to the nitrogen-containing heterocyclic structure of the compound, the nitrogen atom on the heterocyclic ring has a certain alkalinity and can react with acids to form salts, which is its characteristic as a nitrogen-containing heterocyclic compound.
In addition, aldehyde groups can participate in nucleophilic addition reactions. For example, under acid catalysis with alcohols, semi-acetals are formed first, and then acetals are formed. This reaction is often used to protect aldehyde groups in organic synthesis. And because its molecular structure contains multiple active check points, under suitable conditions, substitution reactions can occur. The hydrogen atoms on the methyl group and heterocyclic ring may be replaced by other groups, and then a variety of derivatives can be derived, which are widely used in the field of organic synthesis.

I don't know if 7 - Methylimidazo [1,2 - a] pyridine - 3 - carbalaldehyde is in the market price range. This is a fine chemical, and its price is determined by many factors. One is purity. If the purity is high, the price will be expensive; if the purity is low, the price will be cheap. Second, it is related to the production scale. Large-scale production, due to cost dilution, the price may tend to be easy; small-scale production, high cost, the price will also rise. Third, the market supply and demand situation is also key. If demand is strong and supply is low, the price will rise; if supply exceeds demand, the price may fall.
The difficulty of its preparation process also affects the price. If the preparation requires complicated steps, special raw materials or harsh conditions, the cost will be high and the price will be high. And different suppliers have different pricing due to their own cost structures and market strategies.
To know the exact price range, check the chemical product trading platform, consult suppliers, or refer to relevant industry reports to get accurate numbers.