7 Methylimidazo 1 2 A Pyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

7-methylimidazo[1,2-a]pyridine-2-carboxylic acid

    Specifications

    HS Code

    539835

    Chemical Formula C9H8N2O2
    Molecular Weight 176.172 g/mol
    Appearance Solid (predicted)
    Boiling Point 361.2°C at 760 mmHg (predicted)
    Melting Point 175 - 177 °C
    Density 1.29 g/cm³ (predicted)
    Logp 1.52 (predicted)
    Pka 3.78±0.20 (predicted)
    Solubility Soluble in organic solvents like DMSO
    Smiles O=C(O)c1cn2c(n1)cccc2C

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid
    7 - methylimidazo [1,2 - a] pyridine - 2 - carboxylic acid, also an organic compound. To clarify its chemical structure, it should be named after its clue solution.
    "7 - methyl" shows that there is a methyl group attached to the position numbered 7 in its structure. "Imidazo [1,2 - a] pyridine" shows that the core of this compound is a fused ring structure of imidazolo [1,2 - a] pyridine. This fused ring is formed by fusing the imidazole ring with the pyridine ring, and the imidazole ring is connected to the pyridine ring in a specific way to form a unique ring structure.
    And "-2-carboxylic acid" indicates that there is a carboxyl (-COOH) functional group connected at the position where the fused ring structure is numbered 2.
    In summary, the chemical structure of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid is imidazolo [1,2-a] pyridine as the parent nucleus, with methyl at the 7th position and carboxylic at the 2nd position. This structure endows the compound with specific physical and chemical properties, and may have important uses in many fields such as organic synthesis and medicinal chemistry.
    What are the main uses of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid
    7-Methylimidazolo [1,2-a] pyridine-2-carboxylic acid, which has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate for the synthesis of many effective drugs. Due to the unique molecular structure and activity of this compound, it can be precisely spliced with other molecules through specific chemical reactions to construct drug molecules with special pharmacological activities to fight various diseases.
    In the field of materials science, it also has unique functions. With its special chemical properties, it can participate in the preparation of functional materials. Or because of its intermolecular interaction properties, it can improve some properties of the material, such as stability, adsorption, etc., so that the material exhibits excellent performance in specific environments and is suitable for the preparation of specific high-end materials.
    In addition, in the field of organic synthesis, it is often used as an important starting material or reaction intermediate. Its chemical structure gives it a variety of reactive activity check points, chemists can use ingenious design of reaction routes to participate in various complex organic reactions, providing the possibility for the construction of complex organic compounds, and promoting the development and innovation of organic synthesis chemistry. In conclusion, 7-methylimidazolo [1,2-a] pyridine-2-carboxylic acids play a key role in many fields and are of great significance to promoting related scientific and technological progress.
    What are the synthesis methods of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid
    The synthesis method of 7-methylimidazolo [1,2-a] pyridine-2-carboxylic acid has been known for a long time. There are many methods and each has its own strengths.
    First, pyridine derivatives are used as starting materials and obtained through multi-step reactions. First, under suitable reaction conditions, such as in an organic solvent, under the action of a certain temperature and catalyst, a substitution reaction occurs to introduce a specific group. Then, through cyclization, the parent nuclear structure of imidazolo [1,2-a] pyridine is constructed. This process requires precise control of the reaction conditions. Too high or too low temperature and improper catalyst dosage may affect the reaction process and product purity. After cyclization, methylation reaction is carried out. Under suitable reagents and conditions, methyl is introduced at a specific position, and finally acidified to obtain 7-methylimidazolo [1,2-a] pyridine-2-carboxylic acid.
    Second, there are also imidazole derivatives as starters. The imidazole derivatives are first modified to have an activity check point connected to the pyridine fragment. Through coupling reaction, the pyridine fragment is connected to the imidazole derivative to form a preliminary framework. After that, a series of functional group transformations, such as oxidation and reduction, adjust the molecular structure to achieve the construction of the target product. This route requires a good understanding of various reaction conditions in order to ensure the smooth progress of each step of the reaction and improve the yield of the product.
    Third, there are methods for using transition metal catalysis. With the help of the unique activity of transition metal catalysts, the relevant substrates are promoted to react. This method has the advantages of mild reaction conditions and high selectivity. However, the cost of transition metal catalysts is higher, and the separation and recovery of catalysts after the reaction are also issues to be considered. In practice, the reaction conditions need to be optimized to reduce the amount of catalyst and improve its recovery rate.
    In practical applications, the above synthesis methods need to be used according to specific needs and conditions, and the advantages and disadvantages should be weighed to choose the best one.
    What are the physical properties of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid
    7-Methylimidazolo [1,2-a] pyridine-2-carboxylic acid. The properties of this substance are related to its melting point, solubility, and stability.
    On its melting point, due to the bonding mode between atoms in the molecule and the interaction between molecules, its melting point is at a specific temperature. The atoms in the molecule are connected by chemical bonds and take a specific spatial configuration. The structure of methyl and imidazolo-pyridine carboxylic acids affects each other. In addition, there are van der Waals forces and hydrogen bonds between molecules, so that the molecule needs to obtain corresponding energy to break the binding and transfer from the solid state to the liquid state. This temperature is the melting point. Similarly, gasification requires more energy to overcome the intermolecular force and reach the boiling point. < Br >
    In terms of solubility, it varies in different solvents. Because of its certain polarity, in polar solvents such as water, it can form hydrogen bonds or other molecular interactions with water molecules, and has certain solubility. However, if the polarity of the solvent is weak and the force between it and the compound is small, the solubility is poor. For example, in non-polar organic solvents such as n-hexane, the solubility is poor.
    Stability is also an important physical property. In molecular structure, the chemical bond energy determines its chemical stability. The chemical bonds formed by each atom in the compound are stable, and it is not easy to break or rearrange chemical bonds without specific conditions. However, under conditions such as strong acid, strong base, high temperature or specific catalyst, the structure may change. For example, in a strong acid environment, the carboxyl group or proton changes its chemical properties; in a strong base, the carboxyl group or salt forms, which affects the overall properties of the molecule.
    In short, the physical properties of 7-methylimidazolo [1,2-a] pyridine-2-carboxylic acid are determined by its molecular structure. The melting point, solubility and stability exhibited under different conditions affect its behavior in various chemical processes and applications.
    What is the market price of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid
    I wonder what you are asking about the market price of 7-methylimidazo [1,2-a] pyridine-2-carboxylic acid. However, the market is changeable, and the price of this compound varies from time to time, and also varies with quality and quantity.
    In the past, the price of such fine chemicals often depended on the state of supply and demand. If there are many people seeking this product, and there are few products, the price will be high; on the contrary, if the supply exceeds the demand, the price may drop. And the difficulty of its preparation is also a variable of the price. If the synthesis path is complicated, and rare raw materials and exquisite skills are required, the cost will be high, and the price will follow.
    Looking at the way of "Tiangong Kaiwu", the price of all things follows the rules of nature. The price of this chemical varies in the market, or due to different origins. The price of Western products and Middle-earth products may be different, or due to different transportation fees and taxes.
    However, I cannot determine the specific price at this moment. If you want to get an accurate number, you can consult the merchant of chemical materials, or check the platform of chemical transactions. There should be real-time prices there to solve your doubts.