7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine

7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine is an organic compound with unique chemical properties. It contains chlorine atoms, methoxy groups and pyrrolido-pyridine structures, which endow it with various chemical activities.
From the perspective of substituents, chlorine atoms have electron-absorbing properties, which can affect the distribution and polarity of molecular electron clouds. Because its electronegativity is greater than that of carbon, the C-Cl bond electron cloud is biased towards chlorine, causing the connected carbon atoms to be partially positively charged, making the position vulnerable to nucleophilic reagents and triggering nucleophilic substitution reactions. For example, in the presence of appropriate basic conditions and nucleophiles, chlorine atoms can be replaced by other groups, such as hydroxyl groups, amino groups, etc., to form different derivatives.
Methoxy group is the power supply group, which can increase the electron cloud density of the pyridine ring through the p-π conjugation effect. This makes the pyridine ring more prone to electrophilic substitution, and the electron cloud density of the methoxy group o and para-position increases more significantly. Electrophilic reagents attack these positions more often. For example, when reacting with halogenating reagents, halogen atoms may preferentially replace methoxy o and para-position hydrogen atoms. The structure of the pyrrolido-pyridine thick ring gives the compound unique stability and electron delocalization properties. Due to the expansion of the conjugate system, the molecular energy decreases and the stability is enhanced. This structure also affects its spectral properties, such as specific absorption peaks in the ultraviolet-visible spectrum, which facilitates structure identification and analysis.
In addition, the solubility and physical properties of the compound are also affected by the structure. Contains polar groups such as methoxy, which make it soluble in polar solvents (such as methanol, ethanol, etc.), but the chlorine atom and fused ring structure limit its solubility in water.
Overall, the chemical properties of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine are determined by the synergy of various groups in its structure. These properties are of great significance in the fields of organic synthesis and medicinal chemistry, and can be used as intermediates for the synthesis of more complex functional molecules.

The common synthesis method of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine follows the conventional path of organic synthesis. The synthesis of this compound often takes a specific nitrogen-containing heterocyclic compound as the starting material and is formed through a multi-step reaction.
Initially, or take a suitable pyridine derivative, the structure needs to contain a modifiable check point for subsequent introduction of the desired group. Through the halogenation reaction, the chlorine atom is introduced at a specific position in the pyridine ring. This step requires precise control of the reaction conditions, such as the reaction temperature, the proportion of reactants and the choice of catalyst, all of which are related to the efficiency and selectivity of the reaction. The halogenating reagents used, such as thionyl chloride, phosphorus oxychloride, etc., are selected according to the characteristics of the substrate and the reaction environment.
Then, through the methoxylation step, a methoxy group is added to the molecule. In this process, commonly used methoxylating reagents such as sodium methoxide, dimethyl carbonate, etc. react with chlorine-containing intermediates in an appropriate solvent. The polarity and alkalinity of the reaction solvent have a great impact on the reaction process and must be carefully considered. This step of the reaction may need to be carried out under conditions such as heating and inert gas protection to promote the smooth occurrence of the reaction and avoid the interference of side reactions.
The construction of pyrrole ring is a key step. It is often achieved by intramolecular cyclization reactions, which often involve the rearrangement of intramolecular chemical bonds and the formation of new bonds. Specific catalysts, such as some transition metal catalysts or organic base catalysts, can be used to reduce the activation energy of the reaction and guide the reaction along the desired path. The regulation of reaction conditions, such as reaction time, temperature and catalyst dosage, is crucial to the formation of pyrrole rings and the purity of the product.
The whole process of synthesis requires a variety of analytical methods to monitor the reaction process, such as thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), etc., to ensure that each step of the reaction achieves the desired effect and the purity and structure of the product meet the requirements. After each step of the reaction, it is often necessary to separate and purify operations, such as column chromatography, recrystallization, etc., to remove impurities and obtain pure products. In this way, through careful operation of various steps, the target compound 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine can be obtained.

7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, an organic compound, has applications in many fields.
In the field of pharmaceutical research and development, it may be a key intermediate. Geinpyridine and pyrrole structures widely exist in many drug molecules and have diverse biological activities. The chlorine and methoxy substituents of this compound can regulate its physicochemical properties and biological activities. For example, by modifying its structure, new drugs with specific pharmacological activities can be developed, or specific targets can be acted on to treat related diseases, such as for some cancer targets, by derivatization of the compound to develop new anti-cancer drugs; or acting on nervous system targets, to develop drugs for treating neurological diseases.
In the field of materials science, organic heterocyclic compounds often have unique photoelectric properties. 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine may participate in the preparation of organic Light Emitting Diode (OLED) materials. Its special molecular structure may endow the material with specific luminescent properties, such as adjusting the luminescence color and efficiency. It can also be used to prepare conductive polymer materials. Due to its structure of π-electron conjugated system, it can improve the conductivity of polymers and has potential application value in the field of electronic devices.
In agricultural chemistry, compounds containing pyridine and pyrrole structures may have insecticidal and bactericidal activities. 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine can be developed into new pesticides after appropriate modification. For example, for specific crop pests or pathogens, pesticides with high selectivity and activity can be designed and synthesized to help agricultural pest control and ensure crop yield and quality.

7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, the market price of this product is difficult to determine. The price often changes for many reasons, such as the difficulty of production, the supply and demand of the market, and the quality.
In the past, if a city official wanted this product, he would have to search for news from many parties, ask merchants, and observe the number of rewards, so as to know the market. Although the information is convenient today, it is not easy to obtain an accurate price.
If it is difficult to make, requires a lot of ingenuity and order, and the materials used are rare, the cost is high, and the price will be high. And if there are many seekers in the market, but the supply is scarce, the so-called "what is rare is expensive", the price will also rise. On the contrary, if it is easy to make, the supply is sufficient, and there are few applicants, the price may become more affordable.
And the quality is different, the price is also different. Those who are pure and flawless and meet strict standards are more expensive than those with slightly more impurities and slightly inferior quality. Therefore, in order to know the exact market price of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, it is necessary to consult people in the industry, observe changes in the market, and comprehensively consider various factors. It is not possible to set the price based on one statement alone, but to review it carefully to avoid mistakes.

The investigation of the safety and toxicity of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine is related to many aspects.
The safety of this compound depends on its chemical structure and properties. The presence of chlorine atoms and methoxy groups in its structure may affect its chemical activity and stability. However, it is difficult to fully understand its performance in complex biological systems from the structure alone.
When it comes to toxicity, it is based on experiments. In the laboratory, animal models are often used for toxicity testing. Looking at its acute toxicity to test animals, if ingested this compound, animals may show signs of abnormal behavior and physiological dysfunction. If the test animal may have reduced activity, abnormal eating and drinking, severe or life-threatening.
Subacute and chronic toxicity cannot be ignored. Long-term low-dose exposure may cause functional and organic lesions of the test animal organs. Or damage important organs such as liver and kidneys, affecting their metabolism and excretion functions.
And if this compound is released in the environment, its ecotoxicity should also be considered. It may have different degrees of impact on aquatic organisms, soil microorganisms, etc., or cause ecosystem imbalance.
However, in order to know the safety and toxicity of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine in detail, rigorous scientific experiments and comprehensive evaluations are still required to obtain accurate conclusions to clarify its potential impact on life, health and the environment.