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What is the main use of 6- (trifluoromethyl) pyridine-3-carboxylic acid?
The main use of (triethylmethyl) amine-3-carboxylate is as a corrosion inhibitor. According to Guanfu's "Tiangong Kaiwu", this agent is widely used in the chemical industry.
Metal-covered objects often encounter corrosion, damage their quality and reduce their lifespan, which is not beneficial for work and use. And (triethylmethyl) amine-3-carboxylate can be attached to the metal surface to form a protective film. This film is dense and strong, and can protect the metal from air, water and other aggressive media.
I still remember "Tiangong Kaiwu" saying: "Hardware is a genus that is prone to rust and rot in case of moisture and gas. If you want to protect it, you need to make good use of various agents." This (triethylmethyl) amine-3 -carboxylate is such a gold protection agent. In many metal instruments and pipes, coating this agent can keep it rust-free for a long time and maintain a good state.
And when it inhibits corrosion, it also has mild properties and does not damage the original quality and properties of the metal. Unlike other agents, although it can inhibit corrosion, it may change the color and hardness of the metal. When this agent can protect gold, its gold-protecting properties are really valuable. Therefore, in today's industries, whether metallurgy, machinery, or construction, where metal protection is involved, (triethylmethyl) amine-3 -carboxylate is a commonly used corrosion inhibitor, which is indispensable.
What are the synthesis methods of 6- (trifluoromethyl) pyridine-3-carboxylic acid?
To prepare 6- (triethylamino) hexyl-3-enoic acid, the following methods can be used:
First, starting with hexenoic acid, and triethylamine under suitable conditions, according to the reaction path of nucleophilic addition. Among them, the double bond of hexenoic acid is the reactive check point, and the nitrogen atom of triethylamine is nucleophilic. The two interact, go through a transition state, and finally obtain the target product. During the reaction, temperature and solvent properties are all related to the rate and yield of the reaction. If a polar aprotic solvent, such as dimethylformamide (DMF), can promote the reaction. The temperature may be controlled in the range of room temperature to moderate heating, about 30-60 degrees Celsius, depending on the specific situation.
Second, it is obtained by the substitution reaction of halogenated hexene and triethylamine salt. First, halogenated hexene is prepared. If a halogenating agent reacts with hexene to obtain a halogenated product. Then, halogenated hexene and triethylamine salt are replaced by triethylamino in the presence of a base. The base can be selected from potassium carbonate, sodium carbonate, etc., in an organic solvent such as acetonitrile, heated to reflux, about 80-100 degrees Celsius, and the reaction can be achieved. The activity of the halogen atom of halogenated hexene, the stability of the triethylamine salt, and the strength of the base all affect the reaction
Third, by the method of allylation reaction. The reaction of allyl-containing reagents with suitable caproic acid derivatives. First convert caproic acid into active derivatives, such as acid chloride or anhydride. Then with allyl reagents, such as allyl borate or allyl Grignard reagents, in the presence of metal catalysts, such as palladium catalysts, the allylation reaction is carried out. The reaction environment needs to be anhydrous and oxygen-free, and the solvent is selected as tetrahydrofuran, etc., to regulate the temperature between low temperature and room temperature. Although the amount of palladium catalyst is small, it plays a key catalytic role in the reaction, which can help the effective introduction of allyl, and then obtain 6- (triethylamino) hexyl-3-enoic acid.
What is the market price of 6- (trifluoromethyl) pyridine-3-carboxylic acid?
What is the price of trienyl methyl in the market today? The price of the tricarboxylate in the market often changes due to various reasons, and it is difficult to know for sure.
Looking at the appearance of various market changes, its price may depend on the quality and quantity of things. Those with high quality and abundant quantity, the price may be high; those with poor quality and small quantity, the price may be low. It is also related to the balance of supply and demand. If those who want it are numerous and those who supply it are thin, the price will increase; if the supply exceeds the demand, the price will be depressed.
And the distance of the place where it is produced and the difficulty of transportation are also related to the price. If the place of origin is close and the transportation is easy, the price may be low; if the place of origin is far away and the transportation is difficult, the price may be high. Furthermore, the world situation and political decrees can disturb the price. World chaos or coup d'état, difficulties in production and obstacles to transportation, the price changes constantly.
Therefore, if you want to know the price of tricarboxylates, you must carefully observe the situation of the current city, interview the people and ask the industry, and look at the quality and quantity, supply and demand, origin and transportation routes, and world trends. Only then can you get a more accurate price. However, the market is not constant, and the price is not constant. Only when you study it in real time can you know its near price.
What are the physicochemical properties of 6- (trifluoromethyl) pyridine-3-carboxylic acid?
(Trimethyl) alkyl-3 -carboxylic acids are chemical substances, and their physicalization properties are special.
In terms of physicality, under normal conditions, they can be either solid or liquid, which is determined by the molecular weight of the molecular phase. If the molecular force is low, and the molecular weight of the phase is large, it is mostly solid; conversely, if the molecular force is weak, the molecular weight is small, and it is easy to form a liquid. The melting and boiling force is also the molecular force. The more the molecular force, the higher the melting and boiling force. In general, because the molecule contains carboxyl groups, it can form a high, so the melting and boiling phase is high. < Br >
In terms of solubility, because it contains a carboxyl group, the carboxyl group can be formed by water molecules, so it has a certain solubility in water. However, the alkyl group in the molecule is partially hydrophobic. If the alkyl group is hydrophobic, it will reduce its solubility in water, and the solubility may increase in soluble substances such as ethanol, ethyl ether, etc.
. The presence of the carboxyl group makes it acidic. It can be neutralized and reversed to form a phase of water. The acidic phase of the weak carboxyl group can increase the acidity of the carboxyl group if it has a absorber group. If there is a subscriber group, it will weaken the acidity of the carboxyl group. In addition, it can be esterified and reversed. Under the catalytic action of sulfuric acid and the like, the alcohol is reversed to form ester water. In the same way, the alkyl group part in the molecule can be substituted and reversed. For example, under light or specific catalytic components, the alkyl atom on the alkyl group can be substituted by the alkyl atom or the like. Therefore, the physicalization of (trimethyl) alkyl-3 -carboxylic acids is determined by its molecules, and it has important uses in chemical synthesis and other fields.
What are the precautions for 6- (trifluoromethyl) pyridine-3-carboxylic acid in storage and transportation?
(Triethylamino) -3-carboxyl group in storage and transportation, when careful to check all things, can keep it safe.
First words storage, this substance should be placed in a cool, dry and well ventilated place. Because of its nature or fear of moisture and heat, it is necessary to avoid direct sunlight and moisture. If exposed to the hot sun or in a humid place, its properties may vary and its effectiveness will be reduced. And it should be placed separately from oxidizing agents, acids, bases and other substances. Due to different chemical properties, mixing can easily lead to chemical reactions and cause danger. Storage containers must be well sealed to prevent volatilization and escape, and can also prevent external impurities from mixing in to maintain their purity.
As for transportation, it is also necessary to pay great attention. You should choose a mode of transportation suitable for the characteristics of this substance. When loading and unloading, handle it with care, and do not drop and collide to avoid damage to the container and material leakage. During transportation, strictly prevent water, rain and high temperature. In case of bad weather, such as heavy rain and extreme heat, you need to pay more attention to protection. Vehicles transported should be clean and stain-free, and equipped with corresponding emergency treatment equipment. Once there is a leak, they can respond immediately and reduce the damage. Transportation personnel must also undergo professional training, familiar with the characteristics of this substance and emergency response methods, so as to ensure safe transportation.