6 Trifluoromethyl Pyridine 3 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

6-(trifluoromethyl)pyridine-3-carbonitrile

    Specifications

    HS Code

    620406

    Chemical Formula C7H3F3N2
    Molar Mass 170.107 g/mol
    Appearance Solid (Typically)
    Melting Point Data may vary, check literature
    Boiling Point Data may vary, check literature
    Density Data may vary, check literature
    Solubility In Water Low (due to non - polar nature of trifluoromethyl group)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Data may vary, check literature
    Flash Point Data may vary, check literature

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    General Information
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    Frequently Asked Questions

    As a leading 6-(trifluoromethyl)pyridine-3-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 6- (trifluoromethyl) pyridine-3-formonitrile?
    (Trimethylphenyl) vinyl trimethylsilane has a unique chemical property of -3-methylpropene. In this substance, the trimethylphenyl part endows it with a certain steric barrier and electronic effect, which makes the whole molecule exhibit special activity in chemical reactions.
    From the perspective of nucleophilic reactions, due to the existence of silicon atoms, its β-carbon has certain nucleophilicity and can participate in nucleophilic substitution reactions under appropriate conditions. When confronted with electrophilic reagents, the π electron cloud on the vinyl double bond can attract the attack of electrophilic reagents, and an electrophilic addition reaction occurs to form a new carbon-electrophilic group bond. The double bond of the methylpropylene part, as an unsaturated bond, is also prone to addition reactions, and can be added with reagents such as hydrogen halide and halogen to enrich its chemical structure.
    In terms of oxidation reaction, the silicon-carbon bond may break under the action of a specific strong oxidant, and the double bond can also be oxidized to the corresponding oxygen-containing functional groups such as carbonyl or hydroxyl. In the polymerization reaction, if there is a suitable initiator, the double bond of vinyl and methylpropylene can initiate polymerization to form polymers with different structures and properties. In the field of organic synthesis, this substance can be used as a key intermediate to construct more complex organic molecular structures due to its unique chemical properties, opening up new paths for many organic synthesis reactions.
    What are the common synthesis methods of 6- (trifluoromethyl) pyridine-3-formonitrile?
    For trivinyl amine-3-ethyl ether, the common synthesis methods are as follows:
    First, the method of reacting alcohol with halogenated hydrocarbons. Take an appropriate alcohol, such as ethanol, and make it react with halogenated hydrocarbons, such as bromoethylene, under the catalysis of bases. Nucleophilic substitution reactions are carried out. Bases, such as potassium carbonate, can promote the formation of oxygen anions in alcohols, which then interact with halogenated atoms in halogenated hydrocarbons, and the halogenated atoms leave to form ether bonds to obtain products. This reaction condition is relatively mild, but halogenated hydrocarbons need to be purified, and the reaction yield is sometimes limited by the activity of halogenated hydrocarbons and the amount of base.
    Second, Williamson synthesis method. Using sodium ethyl alcohol and vinyl bromide as raw materials, the ethoxy negative ion of sodium ethyl alcohol has strong nucleophilicity, attacking the β-carbon of bromoethylene, and the bromine ion leaves to form trivinyl amine-3-ethyl ether. This reaction has good selectivity, but sodium ethyl alcohol needs to be prepared on site, which requires strict water-free reaction environment. Otherwise, sodium ethyl alcohol is easy to hydrolyze and deactivate, which affects the formation of products.
    Third, alkoxylation reaction of olefins. Ethylene and ethanol are used as starting materials, and in the presence of catalysts, such as some transition metal catalysts, ethylene is alkoxylated. This reaction has high atomic economy and conforms to the concept of green chemistry. However, the catalyst is expensive, and the reaction conditions are harsh, requiring specific temperature and pressure, which requires high equipment and restricts its wide application.
    Each method for synthesizing trivinylamine-3-ethyl ether has its own advantages and disadvantages. The practical application needs to be weighed according to the availability of raw materials, cost, product purity and other factors, and the appropriate method should be selected.
    In which fields is 6- (trifluoromethyl) pyridine-3-formonitrile used?
    (Trimethylmethyl) is used for its use of trimethylphenol, which is more effective.
    Trimethylphenol, the use is more effective. First, in the field of production, it can be used as a raw material for some kinds of flavors to help in the synthesis of compounds, so that the efficiency is more effective, and it is beneficial to the treatment of diseases. Second, in the chemical industry, trimethylphenol can be used in raw chemical products, such as the synthesis of special lipids. This fat is important for materials, adhesives, etc., which can increase the adhesion and corrosion resistance of materials, and improve the stickiness of adhesives. In addition, in the manufacture of fragrances, trimethylphenol can be used as a component of fragrance blending, which can give the fragrance a special flavor and add its fragrance several times. It is used in the production of high-quality perfumes and flavors.
    And (trimethylmethyl) to the other, or because the two have mutual effects on the chemical properties, can cooperate with each other in the chemical reaction and product manufacturing, and achieve better results. Or in a specific reaction, some groups of (trimethylmethyl) can combine with the active site of trimethylphenol, and change the reaction path, so as to obtain the required compounds, which can be used in the above-mentioned chemical, chemical, fragrance and other fields to provide assistance for the development of the phase.
    What is the market price of 6- (trifluoromethyl) pyridine-3-formonitrile?
    In today's market, the prices of (Sanxiang methyl) ketone and 3-methyl butyraldehyde vary with the supply and demand of the market and the production situation.
    The price of all chemical raw materials is determined by the number of people. First, the supply and demand situation is also. If there are many people in the market who want (Sanxiang methyl) ketone and 3-methyl butyraldehyde, but the production cannot be given, the price will rise; on the contrary, if the supply exceeds the demand, the stock is too large and difficult to sell, and the price will drop.
    Second, the cost of production is also heavy. The price of raw materials, human resources, equipment consumption, factory rent, etc., are all related to costs. If all fees increase, the price of the product will also have to rise; if costs can be saved and efficiency can be increased, the price may be stable and reduced.
    Third, government decrees, regulations and market regulation also have an impact. If environmental protection orders are strict, factories have to spend huge sums of money to cope with them, and costs will increase and prices will change. Or there are trade policies and tariff adjustments, which can make prices fluctuate.
    Fourth, competition in the industry is also an important reason. Factories compete, or for market expansion and customer supply, and there are those who take price as the edge. If there is a fierce competition among the same industry, or those who reduce their prices to attract customers; factories in single or small cities have more power over price control.
    Therefore, in order to know the market price of (Sanxiang methyl) ketone and 3-methyl butyraldehyde, we must look at the supply and demand, cost, government orders, competition, etc., in order to obtain a more accurate judgment. However, the market conditions are ever-changing, and the price is also variable.
    What are the storage conditions for 6- (trifluoromethyl) pyridine-3-formonitrile?
    The storage of Sanxiang methyl ester should be placed in a cool and dry place, and it should be kept away from fire and heat sources. This is because of its flammability, it is easy to burn in case of open flames and hot topics, causing harm.
    In addition, it is necessary to avoid mixing with strong oxidants. Strong oxidants have strong oxidizing properties and meet Sanxiang methyl ester, or cause violent chemical reactions, cause material deterioration, or even risk explosion.
    Storage places should also be well ventilated to reduce the concentration of Sanxiang methyl ester in the air and prevent it from accumulating to the limit of explosion. At the same time, clear warning signs should be set up to make everyone aware of its danger and exercise caution.
    In addition, there are strict requirements for storage temperature. If the temperature is too high, the vapor pressure of Sanxiang methyl ester increases, and the volatilization intensifies, which not only damages its quality, but also increases the risk of fire and explosion. Therefore, it is usually necessary to control the temperature within a suitable range to ensure its stability and safety.
    The choice of storage container is also very critical. When the material is well adapted and well sealed, it can prevent Sanxiang methyl ester from leaking. If it leaks, it will not only cause material loss, but also volatilize in the air, increasing safety hazards and polluting the environment.
    In short, in order to properly store tri-Sanxiang methyl ester, we must consider all the above conditions in an all-round way and operate in strict accordance with regulations to ensure its safety and avoid accidents.