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What is the main use of 6-tert-butyl 3-methyl 2-amino-4,5-dihydrothieno [2,3-c] pyridine-3,6 (7H) -dicarboxylate
6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate, which is widely used. In the field of medicine, it is a key intermediate for the synthesis of new drugs. The characteristics of this structure can give specific activity and selectivity to drugs, or can be used to develop drugs for the treatment of specific diseases, such as certain inflammation, neurological diseases, etc. Due to the presence of specific groups, the drug is easier to bind to the target target, improve efficacy and reduce adverse reactions.
In the field of materials science, it can be chemically modified to introduce it into polymer materials. With its unique chemical structure, it may improve the properties of materials, such as enhancing material stability, thermal stability, optical properties, etc. This material may be applied to optoelectronic devices, polymer composites and other fields to meet the needs of different scenarios.
In organic synthesis research, as an important building block for organic synthesis, it can participate in various organic reactions and build more complex organic molecular structures. Chemists explore and regulate their reactivity check points to develop novel synthesis methods and routes, expand the boundaries of organic synthesis chemistry, and lay the foundation for the creation of more new organic compounds.
From this perspective, 6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate has important potential application value in many fields such as medicine, materials and organic synthesis, and has broad prospects.
What are the synthesis methods of 6-tert-butyl 3-methyl 2-amino-4,5-dihydrothieno [2,3-c] pyridine-3,6 (7H) -dicarboxylate
To prepare 6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate, there are various methods.
First, a thiophenopyridine ring system can be constructed from a suitable starting material through a multi-step reaction. First, a compound containing thiophene structure and a pyridine derivative are used under suitable reaction conditions, such as in a specific organic solvent, and a base is used as a catalyst to carry out a condensation reaction to form a preliminary ring structure. Subsequently, for this intermediate, substituents such as tert-butyl and methyl are introduced at specific positions. When tert-butyl is introduced, tert-butyl reagents, such as tert-butyl halide, can be selected to react under metal catalysts or alkaline conditions. When methyl is introduced, methylating reagents, such as iodomethane, can be used to react in an alkaline environment. After that, the amino and carboxyl ester groups are precisely modified to obtain the target product.
Second, a compound with a partial target structure can also be used as a starting material. The remaining structure is gradually constructed through selective functional group conversion. For example, a compound containing a partial structure of thiophenopyridine is first formed by a specific reduction reaction to form a 4,5-dihydro structure. Then, the amino group is introduced through the amination reaction. In this process, suitable amination reagents and reaction conditions need to be selected to ensure the selectivity and yield of the reaction. Finally, through the esterification reaction, carboxyl ester groups are introduced, and the reaction conditions are controlled, so that both carboxyl groups are converted into corresponding esters, thereby obtaining 6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate.
These two methods are only examples. In actual synthesis, it is necessary to optimize the synthesis route according to many factors such as the availability of starting materials, the controllability of reaction conditions, and the purity requirements of the target product, in order to achieve efficient and economical synthesis goals.
What are the physicochemical properties of 6-tert-butyl 3-methyl 2-amino-4,5-dihydrothieno [2,3-c] pyridine-3,6 (7H) -dicarboxylate
6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate, this is an organic compound with unique physicochemical properties.
Looking at its properties, it is mostly in a stable solid state at room temperature and pressure. The melting point of this compound is of great significance for its physical state transition under specific conditions, but the specific values vary depending on the preparation and purity. < Br >
In terms of solubility, because its molecular structure contains specific functional groups, it exhibits a certain solubility in organic solvents such as dichloromethane, chloroform, and N, N-dimethylformamide. This property is crucial in the selection of reaction solvents and product separation in organic synthesis.
Stability is also a key property. Under conventional environmental conditions, if there are no special chemical reagents or strong external factors, the compound is structurally stable and can be stored for a long time. However, in the case of strong acids and strong bases, sensitive chemical bonds in its molecular structure, such as ester groups and amino groups, are vulnerable to attack, triggering chemical reactions and causing structural changes.
As for its chemical properties, the presence of amino groups endows the compound with alkalinity, which can neutralize with acids to form corresponding salts. Ester groups have hydrolytic activity, and can be hydrolyzed under acidic or basic conditions. Carboxylic acids and alcohols can be obtained by acidic hydrolysis, and carboxylates and alcohols can be generated by basic hydrolysis. The thiophene-pyridine ring structure endows the compound with certain aromaticity, enabling it to participate in various electrophilic substitution reactions, such as halogenation, nitrification, etc., and has broad application prospects in the field of organic synthesis.
What is the price range of 6-tert-butyl 3-methyl 2-amino-4,5-dihydrothieno [2,3-c] pyridine-3,6 (7H) -dicarboxylate in the market?
Wuweiwen has the exact price of 6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylate for sale in the market. This compound may be a rare chemical or used in niche fields such as specific scientific research and pharmaceutical synthesis.
Its price often varies depending on purity, dosage, supplier and market supply and demand. If high purity (such as more than 98%) and small dosage (such as gram grade) are required, the price per gram may be hundreds or even thousands of yuan for fine chemical suppliers. Because of its synthesis or involving complex steps, specific reagents and conditions, the cost is high.
If it is an industrial-grade dosage (above the kilogram level), and the purity requirements are slightly lower, the price may drop due to the scale effect. However, the difficulty of its synthesis process still makes the price not too low, between thousands and tens of thousands of yuan per kilogram.
However, to know the exact price range, you must consult various chemical suppliers, such as Sigma-Aldrich, Alfa Aesar and other internationally renowned companies, or domestic suppliers such as Buckingway, Tixi Ai, etc., subject to their quotations. And the market price also changes at any time, so real-time inquiry is often required.
What are the application fields of 6-tert-butyl 3-methyl 2-amino-4,5-dihydrothieno [2,3-c] pyridine-3,6 (7H) -dicarboxylate
6-tert-butyl-3-methyl-2-amino-4,5-dihydrothiopheno [2,3-c] pyridine-3,6 (7H) -dicarboxylic acid esters have a wide range of uses. In the field of medicinal chemistry, such compounds are often key intermediates for the development of new drugs. Due to their unique structure, they can be carefully modified and modified by organic synthesis, so it is expected to create molecules with specific pharmacological activities. It may act on specific biological targets, such as enzymes, receptors, etc., and has potential applications in the treatment of many diseases, such as anti-tumor, anti-infection, and treatment of neurological diseases.
In the field of materials science, it may also have outstanding performance. Due to the characteristics of thiophene and pyridine structural units, this compound is endowed with unique electrical and optical properties. Or it can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diode (OLED), components of organic solar cells, etc., to contribute to the development of energy and display technology.
In the field of agricultural chemistry, such compounds may be designed to be converted into new pesticides. With its ability to regulate specific biological activities, high-efficiency, low-toxicity and environmentally friendly insecticides, fungicides, etc. can be developed to help protect and increase crop production. It has potential application value in many aspects such as organic synthesis, drug research and development, material creation and agricultural protection, and the prospect is quite promising.