6 Oxo 1 6 Dihydropyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

6-oxo-1,6-dihydropyridine-3-carboxylic acid

    Specifications

    HS Code

    358718

    Chemical Formula C6H5NO3
    Appearance Solid
    Color Typically white or off - white
    Odor Odorless (usually)
    Melting Point Data needed for accurate value
    Boiling Point Data needed for accurate value
    Solubility In Water Limited solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents
    Pka Value Data needed for accurate value
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 6-oxo-1,6-dihydropyridine-3-carboxylic acid?
    6-Oxo-1,6-dihydropyridine-3-carboxylic acid has a unique chemical structure. Looking at this name, "6-oxo" has a monocarbonyl group ($C = O $) at the 6th position of the pyridine ring, which has a great influence on the reactivity and physical properties of the compound. "1,6-dihydropyridine" shows that the 1st and 6th positions of the pyridine ring are dihydro states, that is, the double bond structure of the original pyridine ring is hydrogenated at this position, resulting in changes in the electron cloud distribution and stability of the pyridine ring. And "-3 -carboxylic acid" explicitly states that there is a carboxylic group ($-COOH $) at the 3rd position of the pyridine ring. The carboxylic group is acidic and can participate in many chemical reactions, such as salt formation, esterification, etc.
    Its overall structure is based on the pyridine ring as the basic skeleton, and the 6-position carbonyl group, the 1-position and 6-position hydrogenation, and the 3-position carboxylic group together build the chemical properties of this compound. Carbonyl groups can participate in nucleophilic addition reactions, and the unsaturation of the dihydropyridine part makes it capable of hydrogenation, oxidation, etc. The acid-base properties of carboxyl groups and the reaction activities of ester formation and amide formation give this compound broad application prospects in organic synthesis, medicinal chemistry and other fields. The various parts in its structure interact with each other and jointly determine the unique physical and chemical properties of the compound.
    What are the common physical properties of 6-oxo-1,6-dihydropyridine-3-carboxylic acid?
    6-Oxo-1,6-dihydropyridine-3-carboxylic acid, that is, 6-oxo-1,6-dihydropyridine-3-carboxylic acid, is a kind of organic compound. Its common physical properties are as follows:
    Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder, which is easy to observe and distinguish. Its color is pure, and the crystalline morphology is regular. Under light, it may be visible with a fine luster, just like a gleaming dust.
    When it comes to solubility, this compound exhibits unique properties in organic solvents. In common organic solvents, such as methanol and ethanol, it has certain solubility. Both methanol and ethanol are polar organic solvents, and there are specific interactions with 6-oxo-1,6-dihydropyridine-3-carboxylic acid molecules, such as hydrogen bonds, van der Waals forces, etc., so they can dissolve them. However, in water, the solubility is relatively limited. Although water is also a polar solvent, the strength and mode of interaction with the compound molecules are different from those of organic solvents, so that the degree of solubility in water is not high.
    When it comes to the melting point, the melting point of this compound is quite high, between 250 ° C and 260 ° C. Determination of the melting point is an important means to identify organic compounds. Such a high melting point indicates that the compound has a strong intermolecular force and a relatively stable structure. A higher temperature is required to destroy the intermolecular force and transform it from a solid state to a liquid state.
    In addition, its stability is also an important physical property. Under normal conditions, the chemical properties are relatively stable. When encountering extreme conditions such as strong acids, strong bases or high temperatures, a chemical reaction may occur, causing its structure to change. This stability is derived from the characteristics of chemical bonds within molecules. The chemical bonds between atoms interact to maintain the stability of the molecular structure. However, under extreme conditions, the chemical bonds may be destroyed, triggering chemical reactions.
    Where is 6-oxo-1,6-dihydropyridine-3-carboxylic acid used?
    6-Oxo-1,6-dihydropyridine-3-carboxylic acid, this is an organic compound that is useful in various fields.
    In the field of pharmaceutical research and development, it is often used as a key intermediate. Due to its unique chemical structure, it can participate in a variety of reactions and assist in the synthesis of molecules with specific biological activities. For example, in the creation of antihypertensive drugs, this compound may be chemically modified to create drugs that inhibit angiotensin-converting enzyme, thereby regulating blood pressure and protecting human health.
    In the field of materials science, 6-oxo-1,6-dihydropyridine-3-carboxylic acid also has potential. Or it can be used to prepare functional polymer materials, by which it can be polymerized with other monomers to give the material special properties, such as improving the solubility and thermal stability of the material, etc., which may be effective in coatings, plastics and other industries.
    In the field of agricultural chemistry, it may also have a place. After appropriate derivatization, it can be made into plant growth regulators, which affect the growth and development process of plants, such as regulating the flowering and fruiting of plants, improving the yield and quality of crops, and adding to agricultural production.
    In the world of organic synthetic chemistry, this compound can be used as the cornerstone for the construction of complex organic molecules due to its lively functional groups, helping chemists create organic compounds with novel structures and unique functions, and promoting the progress of organic chemistry.
    What are the preparation methods of 6-oxo-1,6-dihydropyridine-3-carboxylic acid
    For 6-oxo-1,6-dihydropyridine-3-carboxylic acids, there are many different methods for preparing them. One method can be started from a suitable pyridine derivative. For example, a pyridine compound is oxidized under specific reaction conditions. Take the appropriate pyridine raw material and dissolve it in a specific solvent, such as a non-protic organic solvent, such as dichloromethane or N, N-dimethylformamide. Then, add a suitable oxidizing agent, such as a high-valent metal oxide or peroxide. Control the reaction temperature and time to oxidize the specific position of the pyridine ring to obtain the 6-oxo structure. < Br >
    Another method can be used to construct this compound through a multi-step reaction. First, the nitrogen-containing compound and the carboxyl-containing compound are condensed to form the prototype of the pyridine ring. In an alkaline environment, such as potassium carbonate or sodium hydroxide as bases, the reaction of the two is promoted. Then, the intermediate of the generated pyridine ring is modified. By selecting suitable reagents and conditions, the desired substituent is introduced into the pyridine ring, and the preparation of 6-oxo-1,6-dihydropyridine-3-carboxylic acid is finally achieved.
    Furthermore, the synthesis path of similar compounds can be referred to, and the similarity of their structures and reaction mechanisms can be adjusted. In the synthesis process, it is necessary to pay attention to the selectivity and yield of the reaction, and carefully optimize the reaction conditions of each step, such as temperature, reactant ratio, reaction time, etc., in order to obtain a higher purity and yield of 6-oxo-1,6-dihydropyridine-3-carboxylic acid.
    What is the market prospect of 6-oxo-1,6-dihydropyridine-3-carboxylic acid?
    6-Oxo-1,6-dihydropyridine-3-carboxylic acid, this product is quite promising in the current market prospect. It has emerged in the field of medicine and is a key intermediate for many drug synthesis. Based on it, a variety of drugs with unique curative effects can be prepared, and it has extraordinary effects in the treatment of diseases.
    In view of the vigorous development of the current pharmaceutical industry, the demand for various high-quality intermediates has surged. 6-Oxo-1,6-dihydropyridine-3-carboxylic acid is widely favored among pharmaceutical R & D and production enterprises because of its unique structure, which can participate in various chemical reactions and synthesize active pharmaceutical ingredients with complex structures.
    Furthermore, in the chemical industry, it also has outstanding performance. It can be used as an important raw material for the synthesis of special materials, adding new vitality to the chemical industry. With the progress of material science, the demand for special performance materials is increasing. Materials made of 6-oxo-1,6-dihydropyridine-3-carboxylic acid have full advantages in specific scenarios, such as the synthesis of some high-performance polymers, which make the materials have better mechanical properties and thermal stability.
    At the market level, due to the expansion of application fields, the demand is on the rise. However, its production process has certain complexity, and some production links require high-end technology and equipment, resulting in limited production scale. However, this is also an opportunity. If any company can overcome technical problems and achieve efficient large-scale production, it will be able to seize the opportunity in the market and enjoy rich returns. Overall, the 6-oxo-1,6-dihydropyridine-3-carboxylic acid market has a bright future and great development potential. It needs to be further explored by all parties.