6 Methyl Imidazo 1 2 A Pyridine 3 Methanol
pyridine pyrrole pyrazine piperidine piperazine

6-methyl-Imidazo[1,2-a]pyridine-3-methanol

    Specifications

    HS Code

    736968

    Chemical Formula C9H10N2O
    Appearance Solid (usually)
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Data needed
    Solubility In Organic Solvents Data needed
    Density Data needed
    Pka Data needed
    Flash Point Data needed

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    General Information
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    Frequently Asked Questions

    As a leading 6-methyl-Imidazo[1,2-a]pyridine-3-methanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 6-methyl-Imidazo [1,2-a] pyridine-3-methanol
    6-Methyl-imidazolo [1,2-a] pyridine-3-methanol, this is an organic compound. Its physical properties, at room temperature or as a solid, because it contains a polar group hydroxyl group, it may have some solubility in polar solvents (such as water and alcohols), but it has poor solubility in non-polar solvents (such as alkanes).
    On its chemical properties, because it contains methanol groups, hydroxyl groups can participate in many reactions. If it can be esterified with acids, it can react with carboxylic acids to form corresponding esters under acid catalysis. This reaction mechanism is that hydroxyl oxygen atoms attack carboxyl carbon atoms and form esters through a series of proton transfer and dehydration steps.
    The imidazolopyridine structure of this compound gives it unique reactivity. Nitrogen atoms have lone pairs of electrons, which can participate in coordination reactions as electron donors and form complexes with metal ions, which may have potential applications in the field of materials science and catalysis. At the same time, the electron-rich properties of the imidazole ring make it prone to electrophilic substitution reactions, such as halogenation, nitrification, etc. The reaction check point may be mainly in the area with high electron cloud density on the imidazole ring.
    In addition, due to the existence of methyl groups, the electron cloud distribution and spatial structure of molecules can be affected, which in turn affects their reactivity and physical properties. The push electron effect of methyl groups may increase the electron cloud density of neighboring atoms, which affects the acidity and alkalinity of compounds and the reaction selectivity.
    What are the main uses of 6-methyl-Imidazo [1,2-a] pyridine-3-methanol
    6-Methyl-imidazolo [1,2-a] pyridine-3-methanol, this is an organic compound that has important uses in many fields.
    In the field of medicinal chemistry, it is often used as a key intermediate. The structure of Geiinimidazolo-pyridine has unique physiological activities, on which a variety of pharmacologically active compounds can be synthesized. Or it can be used to develop antibacterial drugs, which can interfere with specific physiological processes of bacteria with their structural properties, such as cell wall synthesis, protein synthesis, etc., to achieve antibacterial effect; it can also play a role in the development of anti-tumor drugs, by regulating specific signaling pathways of tumor cells, inhibiting the proliferation and metastasis of tumor cells.
    In the field of materials science, it also has application potential. Because its molecular structure contains specific functional groups, or it can participate in material synthesis reactions, giving materials unique properties. For example, when preparing photoelectric materials, introducing them into the molecular structure of materials can improve the photoelectric conversion efficiency of materials, so that materials can exhibit excellent properties in photoelectric devices such as solar cells, Light Emitting Diodes, etc.
    In the field of organic synthetic chemistry, it is an important synthetic building block. Chemists can construct more complex organic molecular structures by performing various chemical modifications on them, such as alkylation, acylation, halogenation, etc. By ingeniously designing the reaction route, a series of organic compounds with novel structures and specific functions can be synthesized from 6-methyl-imidazolo [1,2-a] pyridine-3-methanol as the starting material, which contributes to the development of organic synthetic chemistry.
    What is the synthesis method of 6-methyl-Imidazo [1,2-a] pyridine-3-methanol
    The synthesis method of 6-methyl-imidazolo [1,2-a] pyridine-3-methanol, although the ancient books do not contain its name, is deduced from the principles of today's chemistry, or there are various paths.
    First, it can be started from suitable pyridine derivatives. Introduce appropriate substituents at specific positions in the pyridine ring to construct the basic skeleton of imidazolo [1,2-a] pyridine. For example, pyridine containing corresponding substituents can be formed into imidazolo [1,2-a] pyridine structure through a series of reactions such as condensation and cyclization. In this process, it is necessary to make good use of various shrinkage agents and catalysts to precisely regulate the reaction conditions and make the reaction proceed in the expected direction.
    Second, imidazole derivatives can also be used. Through ingenious design of the reaction, the pyridine part is connected to it to construct the target structure. In this path, the selection of the reaction check point and the control of the reaction activity are extremely critical. Or use nucleophilic substitution, electrophilic addition and many other reaction types to gradually splice molecular fragments.
    Wait for imidazolo [1,2-a] pyridine skeleton to be obtained, and then introduce methanol at the 3rd position. The nucleophilic substitution reaction can be used to react with imidazolo [1,2-a] pyridine intermediates with suitable hydroxymethyl reagents. During the reaction, attention should be paid to the activity of the reagent, the selection of the reaction solvent, and conditions such as temperature and time. If a suitable base can promote the activity of the nucleophilic reagent, a specific organic solvent may optimize the reaction environment, making the reaction efficient and selective.
    Or there are other synthesis methods, but they all need to follow the principles of chemistry, study the reaction conditions carefully, observe the characteristics of each intermediate, and repeatedly try to find a suitable synthesis path to obtain this 6-methyl-imidazolo [1,2-a] pyridine-3-methanol.
    What are the precautions for 6-methyl-Imidazo [1,2-a] pyridine-3-methanol in storage and transportation?
    6-Methyl-imidazolo [1,2-a] pyridine-3-methanol is a very important chemical substance. When storing and transporting, many key points must be paid attention to.
    Primary storage environment. This substance should be stored in a cool, dry and well-ventilated place. If it is placed in a high temperature environment, or due to high temperature, its chemical properties will change, or even cause decomposition. If it is extremely hot in summer, if there is no good cooling measures in the warehouse, the temperature will rise, which may damage the stability of the substance. Humid environment is also not advisable, because it may absorb moisture and affect the purity and quality, so moisture protection is extremely critical. A desiccant can be placed in the storage place to maintain dryness.
    Furthermore, attention should be paid to the packaging. Packaging materials with good sealing performance should be used to prevent contact with air. The substance may react with oxygen, carbon dioxide and other components in the air, causing it to deteriorate. If the packaging is damaged, air intrudes, or the substance oxidizes, changing its chemical structure and properties.
    When transporting, stability is of paramount importance. Avoid violent vibration and collision, because the internal structure of the substance may be affected or chemical reactions may be triggered under the shock and collision. And the means of transportation should also maintain suitable temperature and humidity to ensure a stable transportation environment.
    In addition, relevant regulations and standards must be followed. Whether it is storage or transportation, it must strictly comply with the management practices of chemical substances to ensure the safety of personnel and the environment is not polluted. During the operation, the staff should also take protective measures to avoid direct contact with the substance to prevent damage to the body. In this way, the safety and stability of 6-methyl-imidazolo [1,2-a] pyridine-3-methanol during storage and transportation can be ensured.
    What is the market price range for 6-methyl-Imidazo [1,2-a] pyridine-3-methanol?
    I haven't heard the exact price of "6-methyl-Imidazo [1,2-a] pyridine-3-methanol" in the market. This is a special compound related to fine chemicals or pharmaceuticals, and its price often varies depending on purity, yield, supply and demand.
    If it is a high-purity and used as a key intermediate in pharmaceutical research and development, its price is high. Gai pharmaceutical research and development requires strict purity, the preparation process is complicated, and it involves many fine synthesis and purification techniques, and the cost is high. Suppose its purity reaches more than 99%, and it is purchased in small batches, the price per gram may exceed a thousand gold.
    However, if the purity is slightly lower, it should be slightly reduced for general chemical research or non-critical reactions. If the purity is about 95%, the batch is slightly larger, and the price per gram may be in the hundreds of gold.
    In addition, market supply and demand also affect its price. If pharmaceutical companies develop new drugs with this structure at a certain time, and the demand exceeds the supply, the price will rise; on the contrary, if the supply exceeds the demand, the price may be downward.
    Furthermore, the prices demanded by different suppliers are also different. Well-known large factories, due to their excellent quality control and good brand effect, may have high prices; while emerging small factories, in order to compete for the market or slightly reduce their prices. In short, to know the exact market price, it is necessary to carefully observe the market dynamics and consult many suppliers.