6 Methyl 3 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

6-Methyl-3-aminopyridine

    Specifications

    HS Code

    909151

    Chemical Formula C6H8N2
    Molar Mass 108.14 g/mol
    Appearance Solid (usually white or off - white)
    Boiling Point Around 252 - 254 °C
    Melting Point 57 - 60 °C
    Density Data may vary, but around 1.1 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, methanol, etc.
    Odor Characteristic amine - like odor
    Flash Point Around 112 °C

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    General Information
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    Frequently Asked Questions

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    What are the chemical properties of 6-Methyl-3-aminopyridine?
    6-Methyl-3-aminopyridine, this is also an organic compound. Its physical properties, at room temperature, are often solid or liquid states, with specific melting points and boiling points. Looking at its chemical properties, it is really interesting.
    First of all, the amino group is an important functional group, which endows this compound with alkalinity. The nitrogen atom in the capped amino group has a lone pair of electrons, which can accept protons. In an acidic environment, it is easy to combine with protons to form corresponding salts. This property allows 6-methyl-3-aminopyridine to react with many acids, just like the fusion of acids and bases, to achieve acid-base neutralization.
    Furthermore, the presence of the pyridine ring makes the compound aromatic. The electron cloud distribution of the aromatic ring is unique, giving it a certain stability. However, due to the characteristics of the electron cloud, the pyridine ring can undergo electrophilic substitution reactions. For example, when encountering electrophilic reagents, the reagents will attack the position with a relatively high electron cloud density on the pyridine ring, and then a substitution reaction will occur, just like an outsider finding a suitable residence and settling in.
    In addition, the introduction of methyl groups also affects its properties. Methyl groups are the electron cloud densities of pyridine rings and amino groups through induction and conjugation effects. This effect may change the reactivity and selectivity of the compound, so that 6-methyl-3-aminopyridine exhibits a unique performance in a specific reaction, like a unique imprint, making it unique on the stage of chemical reactions.
    And because of its nitrogen-containing atoms, 6-methyl-3-aminopyridine can be used as an important intermediate in the field of organic synthesis. With its amino-pyridine ring reactivity, it can participate in many organic reactions, laying the foundation for the construction of more complex organic molecular structures, like the cornerstone of a high-rise building, and plays a key role in the grand project of organic synthesis.
    What are the physical properties of 6-Methyl-3-aminopyridine?
    6-Methyl-3-aminopyridine is a kind of organic compound. Its physical properties are quite characteristic and have been applied in many fields.
    Looking at its properties, under room temperature, 6-methyl-3-aminopyridine is a solid, which is its significant appearance characteristic. As for the color, it is mostly white to light yellow, and the color is relatively light.
    When it comes to the melting point, it is usually within a certain range, and the specific value is about [X] ° C. The characteristics of the melting point are of great significance in the purification and identification of compounds, and can help to distinguish the purity and characteristics of this substance.
    The boiling point is also a key physical property, about [X] ° C. The existence of the boiling point determines the process of its conversion from liquid to gaseous state under specific temperature conditions, which has a great impact on its chemical production and separation processes.
    In terms of solubility, 6-methyl-3-aminopyridine exhibits a certain solubility in some organic solvents. For example, it can be soluble in common organic solvents such as ethanol and ether. This solubility characteristic provides convenient conditions for its treatment as a reactant, intermediate or product in organic synthesis reactions, and facilitates the construction of the reaction system and subsequent separation operations.
    In addition, the substance has certain stability, but under specific conditions, such as high temperature and strong acid-base environment, chemical reactions will also occur, changing its chemical structure and properties.
    Due to its unique physical properties, 6-methyl-3-aminopyridine is used in many fields such as medicine, pesticides, and materials science. In the field of medicine, it can be used as a key intermediate for the synthesis of specific drugs; in the development of pesticides, it contributes to the development of new pesticides; in the field of materials science, or participates in the synthesis of functional materials to help optimize the properties of new materials.
    What are the main uses of 6-Methyl-3-aminopyridine?
    6-Methyl-3-aminopyridine is also an organic compound. Its use is quite extensive, and it plays an important role in the synthesis of medicine. Due to its unique structure, it can provide a key building block for the creation of new drugs. The synthesis of many antibacterial and anti-inflammatory drugs often relies on this as the starting material. After many delicate transformations, it eventually becomes a good medicine, which is the foundation for healing diseases and saving the world.
    In the field of pesticides, it also has extraordinary performance. It can be used as an important intermediate for the synthesis of new pesticides, helping to develop efficient, low-toxicity and environmentally friendly pesticide varieties, protecting crops from pests and diseases, and ensuring the hope of a bumper harvest.
    Furthermore, in the field of materials science, it has also emerged. With its own chemical properties, it can participate in the preparation of special materials. For example, the participation of some functional polymer materials, 6-methyl-3-aminopyridine, can endow materials with unique properties, such as improving the stability and conductivity of materials, etc., contributing to the development of materials science and promoting its continuous improvement to meet various cutting-edge needs.
    What are 6-Methyl-3-aminopyridine synthesis methods?
    The synthesis method of 6-methyl-3-aminopyridine used to follow various paths. One method is to use 6-methyl-3-nitropyridine as the starting material and obtain it by reduction. Because nitro is easily reduced to amino groups, iron powder and hydrochloric acid are often used as reducing agents. Under appropriate temperature, pressure and solvent environment, the iron powder gradually dissolves, and its electrons transfer to the nitro group, then the nitro group is reduced to amino group, and 6-methyl-3-aminopyridine is obtained. In this reaction, the properties of the solvent, the control of temperature, and the proportion of materials are all key, and the yield is not good. < Br >
    is also prepared by halogenation and aminolysis of pyridine derivatives. The pyridine derivatives are first halogenated under appropriate conditions and halogen atoms are introduced. This halogen has good activity and can react with ammonia or ammonia derivatives. The halogen is replaced by an amino group to form 6-methyl-3-aminopyridine. During halogenation, the type of halogenating agent used and the fine regulation of the reaction conditions all affect the position and degree of halogenation; during aminolysis, the concentration and reaction time of ammonia are also related to the purity and yield of the product.
    is also synthesized by metal-organic chemistry. The specific reaction between metal-organic reagents and pyridine derivatives is used to precisely construct the target molecule. Such as palladium-catalyzed coupling reaction, with the help of the unique activity of palladium catalyst, the reagent containing a specific functional group is coupled with a pyridine derivative, and then the subsequent conversion is obtained to obtain 6-methyl-3-aminopyridine. This method requires strict reaction conditions, and the selection of catalysts and the design of ligands need to be carefully conceived in order to achieve the purpose of efficient synthesis.
    What are the precautions in storage and transportation of 6-Methyl-3-aminopyridine?
    For 6-methyl-3-aminopyridine, many matters need to be paid attention to during storage and transportation.
    This substance has certain chemical activity. When stored, the first environment is dry. Moisture can easily cause it to deteriorate and damage the quality. It should be placed in a dry and well-ventilated place, away from water sources and humid places.
    Furthermore, temperature is also critical. Excessive temperature may cause it to evaporate, or even cause chemical reactions; too low temperature may change the form of the substance, affecting its performance. Therefore, a suitable temperature should be maintained. Generally speaking, room temperature or slightly lower than room temperature is appropriate.
    The choice of storage container should not be ignored. Materials that can withstand their chemical properties, such as glass, specific plastics, etc., must be used to prevent the container from reacting with substances, causing contamination or leakage.
    During transportation, stability is of paramount importance. Ensure that the packaging is firm, avoid collisions and vibrations, and prevent damage to the container. And transport vehicles need to have appropriate protective measures to deal with emergencies.
    At the same time, because of its toxicity and irritation, when operating and contacting, personnel must follow strict safety procedures and wear protective equipment, such as gloves, masks, goggles, etc., to ensure their own safety.
    In addition, whether it is stored or transported, it is necessary to strictly follow relevant regulations and standards, and make labels and records for traceability and management, so as to ensure the safety of 6-methyl-3-aminopyridine during storage and transportation.