6-Methyl-2-pyridinecarbonitrile

6 - Methyl - 2 - pyridinecarbonitrile is an organic compound with specific chemical properties. Its appearance is mostly white to light yellow crystalline powder, which is stable at room temperature and pressure.
When it comes to physical properties, the melting point is about 63 - 67 ° C. This characteristic is crucial for the identification, separation and purification of this compound. Because its melting point is relatively clear, the purity can be determined by melting point determination.
In terms of chemical properties, cyanyl (-CN) is its active site. Cyanyl groups have high reactivity and can participate in a variety of chemical reactions. For example, in the hydrolysis reaction, under the catalysis of acid or base, the cyanyl group can be converted into carboxyl group (-COOH) to form 6-methyl-2-pyridinecarboxylic acid. This reaction is often used in organic synthesis to prepare pyridine compounds containing carboxyl groups.
It can also carry out reduction reaction. Under the action of suitable reducing agent, the cyanyl group can be reduced to amino group (-NH2O) to obtain 6-methyl-2-pyridinecylamine, which is widely used in the field of drug synthesis and the preparation of nitrogen-containing heterocyclic compounds.
In addition, the methyl group on the pyridine ring of this compound also has certain reactivity and can undergo substitution reaction. If under appropriate conditions, the hydrogen atom on the methyl group can be replaced by the halogen atom, which lays the foundation for the subsequent introduction of other functional groups and expands the chemical diversity of the compound.
6 - Methyl - 2 - pyridinecarbonitrile Due to its unique chemical properties, it is widely used in the fields of medicine, pesticides and materials science. In the field of medicine, it is used as a key intermediate for the synthesis of biologically active pyridine drugs; in the field of pesticides, it can participate in the preparation of new pesticides with high efficiency and low toxicity; in the field of materials science, it can be chemically modified to prepare functional materials with special properties.

6-Methyl-2-pyridinecarbonitrile, often synthesized by the following methods:
First, 6-methyl-2-pyridinecarboxylic acid is used as the starting material. First, it is heated with thionyl chloride, which is the key step in converting the carboxyl group to the acid chloride. In the reaction, the chlorine atom of thionyl chloride replaces the hydroxyl group of the carboxyl group, and escapes sulfur dioxide and hydrogen chloride gas. Then, the resulting acid chloride is reacted with sodium cyanide in a suitable solvent. This step can cause the cyanyl group to replace the chlorine atom of the acid chloride, thereby obtaining 6-methyl-2-pyridinecarbonitrile. This path step is clear, but it is necessary to pay attention to the toxicity and corrosiveness of the reagents used. < Br > Second, 2-chloro-6-methylpyridine is used as the raw material. It is heated with sodium cyanide in a polar solvent in the presence of a suitable phase transfer catalyst. The phase transfer catalyst can help cyanide ions cross the two-phase interface, improving the reaction rate and yield. The chlorine atom is replaced by cyanyl group, and the final product is obtained. This method is relatively direct, but the acquisition of the raw material 2-chloro-6-methylpyridine may require a pre-reaction.
Third, 6-methylpyridine is used as the starting material. First, nitro is introduced at the 2-position of the pyridine ring through nitrification. This step requires careful control of the reaction conditions. Due to the special distribution of the electron cloud of the pyridine ring, the nitrification check point has a specific selectivity. Then, the nitro group is reduced to an amino group, and the commonly used reducing agents such as iron filings and hydrochloric acid are used. Then, the amino group is diazotized, and then reacted with cuprous cyanide, and the diazo group is replaced by cyanyl group to obtain 6-methyl-2-pyridineformonitrile. There are many steps in this path, and the process is complicated, but the source of raw materials may be more extensive.
All synthesis methods have advantages and disadvantages. The practical application needs to be weighed according to the availability of raw materials, cost, yield and environmental protection.

6-Methyl-2-pyrimethonitrile is useful in various fields.
In the field of pharmaceutical creation, this compound is often a key intermediate. Due to its unique chemical structure, it can be derived from biologically active drug molecules through a series of reactions. For example, when developing targeted drugs for specific diseases, 6-methyl-2-pyrimethonitrile can be used as a starting material to build complex and curative drug structures through ingenious synthetic pathways, providing powerful tools for combating difficult diseases.
It also has a place in the field of materials science. Or can participate in the synthesis of special polymer materials, giving the material unique properties, such as improving the stability and optical properties of the material. For example, the preparation of polymers with special optoelectronic properties, the addition of 6-methyl-2-pyridyl formonitrile can optimize the electron transport performance of the polymer, and improve the luminous efficiency and stability of the device in the manufacture of organic Light Emitting Diode (OLED) devices, so that the display technology can be refined.
In the field of pesticide chemistry, 6-methyl-2-pyridyl formonitrile can also play an important role. Based on it, high-efficiency and low-toxicity pesticide products can be developed. By modifying and optimizing its structure, compounds with unique insecticidal, bactericidal or herbicidal activities can be synthesized to precisely combat crop pests and diseases, ensure a bumper harvest of agricultural production, and reduce the negative impact on the environment, which is in line with the current needs of green agriculture development.
In summary, 6-methyl-2-pyrimethonitrile has shown important application value in many fields such as medicine, materials, and pesticides, and has contributed a lot to promoting scientific and technological progress in various fields.

6 - Methyl - 2 - pyridinecarbonitrile, that is, 6 - methyl - 2 - pyrimethonitrile, its market price varies due to a variety of factors.
This compound is widely used in chemical and pharmaceutical fields. In chemical industry, it is often a key raw material for organic synthesis, assisting in the preparation of many complex organic compounds; in medicine, or an important intermediate for the synthesis of specific drugs, it is of great significance for the development of new drugs.
Its price is mainly affected by the cost of raw materials. If the source of raw materials required for the preparation of 6 - methyl - 2 - pyrimethonitrile is scarce, difficult to obtain or expensive to extract, its price will rise. If the raw materials are affected by the season, origin, and market supply and demand, the price fluctuates frequently.
The difficulty and cost of the production process are also the key. If production requires complex equipment, harsh conditions, and high-end technology, the cost will increase and the price will rise. And the complex process often leads to low production efficiency and low output, which will push up the price.
The market supply and demand situation also affects the price. Demand is strong. If the pharmaceutical industry is enthusiastic about the research and development of new drugs containing this ingredient, the demand will exceed the supply, and the price will rise; conversely, the demand will be low, the supply will exceed the demand, and the price will drop.
Regional differences also have an impact. Different regions have different prices due to different economic levels, industrial layouts, and logistics costs. In economically developed areas with concentrated industries, prices may be relatively reasonable due to competition and scale effects; in remote areas with scarce industries, prices may be relatively high due to high logistics and operating costs.
According to market conditions, the price of 6-methyl-2-pyriformonitrile fluctuates from tens to hundreds of yuan per kilogram. For specific prices, you need to consult suppliers in detail when purchasing, and comprehensively consider factors such as quality, quantity, and transaction terms to obtain accurate quotations and optimal procurement plans.

6-Methyl-2-pyridineformonitrile, which is an organic compound. This substance is a white to light yellow crystalline powder and is stable at room temperature and pressure.
In terms of its physical properties, the melting point is between 46 and 49 ° C, which makes it change state at a specific temperature range. The boiling point is about 244 ° C, indicating that a higher temperature is required to make it boil and vaporize. The relative density (water = 1) is about 1.1, reflecting its relationship with the density of water. In addition, it is slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, etc. This solubility property is due to the interaction between its molecular structure and the solvent molecules.
These physical properties are crucial for their application in chemical synthesis, pharmaceutical manufacturing and other fields. Melting point and boiling point determine the choice of temperature conditions during the reaction process, and solubility affects its participation in various chemical reaction systems and reaction processes. It has important guiding significance for related industrial preparation processes, product purification and other links.