As a leading 6-methyl-2-(4-methylphenyl)imidazo[1,2-alpha]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 6-methyl-2- (4-methylphenyl) imidazo [1,2-alpha] pyridine
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, this is an organic compound. Looking at its name, its structure can be deduced according to chemical nomenclature. "6-methyl" shows that the 6th position of the imidazolo [1,2-α] pyridine parent nucleus is connected to a methyl group. "2 - (4-methylphenyl) ", that is, the 2nd position of the parent nucleus is connected to a phenyl group, and the 4th position of the phenyl group has another methyl group.
The imidazolo [1,2-α] pyridine parent nucleus is formed by fusing the imidazole ring with the pyridine ring. The imidazole ring is a five-membered heterocyclic ring containing two nitrogen atoms, and the pyridine ring is a six-membered heterocyclic ring containing one nitrogen atom. The two are fused in a specific way to form this unique parent nuclear structure.
The methyl group at position 6 is connected to the parent nuclear carbon atom by a single bond. The benzene ring at position 2 is a six-membered carbon ring with a conjugated π electron system. The methyl group at position 4 is also connected to the benzene ring carbon atom by a single bond.
In this compound structure, each atom is connected by a covalent bond to form a stable organic molecular structure. The exact stereochemical structure may vary depending on the spatial orientation of substituents and intramolecular interactions, but only according to the given name, the above basic planar structure information can be obtained.
What are the main uses of 6-methyl-2- (4-methylphenyl) imidazo [1,2-alpha] pyridine
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, this is an organic compound. It has a wide range of uses and can play an important role in many fields.
In the field of medicine, it may have potential medicinal value. After research, it has been found that these compounds may show therapeutic effects on specific diseases. They may act on specific targets in the human body and regulate physiological functions. For example, in the treatment of neurological diseases and cardiovascular diseases, some compounds containing similar structures have shown active activity. This compound may also have similar effects and can be used as a lead compound for in-depth research and development to help create new drugs.
In the field of materials science, due to the unique structure and properties of organic compounds, 6-methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine may be used to prepare new functional materials. For example, in the field of photoelectric materials, it may be able to achieve the functions of absorption, emission or conduction of light by virtue of its molecular structure characteristics, providing new ideas for the development of new photoelectric materials for the manufacture of more efficient Light Emitting Diodes, solar cells and other devices.
In the field of organic synthesis, as an important intermediate, it can participate in the construction of many complex organic molecules. With its specific functional groups and reactivity, it can combine with other organic reagents to synthesize organic compounds with special structures and functions through various chemical reactions, such as nucleophilic substitution, addition reactions, etc., providing a key material basis for the development of organic synthetic chemistry and expanding the variety and application range of organic compounds.
What are the physical properties of 6-methyl-2- (4-methylphenyl) imidazo [1,2-alpha] pyridine
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, which is an organic compound. Its structure consists of an imidazolo-pyridine parent nucleus, together with 6-methyl and 2 - (4-methylphenyl) substituents. Its physical properties are particularly critical, and it is related to the application of this compound in various fields.
In terms of properties, under normal circumstances, 6-methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine is mostly white to off-white crystalline powder. This form is easy to store and use, and is easy to handle in many chemical operations.
In terms of solubility, its performance in organic solvents is worth exploring. This compound is slightly soluble in common organic solvents, such as ethanol and acetone. In ethanol, with the increase of temperature, the solubility increases slightly. Due to the increase of temperature, the thermal motion of molecules intensifies, and the force between solvent and solute molecules changes. However, in water, its solubility is very small. Due to its molecular structure, hydrophobic aromatic rings account for a large proportion of alkyl groups, and it is difficult to form an effective force with water molecules.
Melting point is also an important physical property. After determination, 6-methyl-2- (4-methylphenyl) imidazolo [1,2-α] pyridine has a specific melting point range. The determination of the melting point can provide an important basis for the purity of the compound. If the purity of the compound is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point decreases and the melting range becomes wider.
In addition, the density of the compound also has its own characteristics. Although the density values or the measurement conditions vary slightly, in general, its density is relatively stable at a certain temperature and pressure. This physical property is very important for application scenarios involving mass and volume conversion.
The physical properties of 6-methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, such as its properties, solubility, melting point, and density, are important guidelines for its application and research in chemical synthesis, drug discovery, and other fields.
What are the synthesis methods of 6-methyl-2- (4-methylphenyl) imidazo [1,2-alpha] pyridine
The synthesis method of 6-methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, although the book "Tiangong Kaiwu" does not directly describe the synthesis of this specific compound, it contains a lot of chemical process wisdom, which may be used as a reference.
To synthesize this compound, one method can be obtained by condensation reaction of pyridine derivatives containing specific substituents and suitable imidazole compounds. First take the pyridine derivative with 6-methyl, carefully remove impurities to ensure purity. Then react with 4-methylbenzaldehyde and related nitrogen-containing reagents to prepare imidazole precursors containing 4-methylphenyl. The two are added to a suitable organic solvent, such as dichloromethane or toluene, an appropriate amount of catalyst, such as concentrated sulfuric acid or p-toluenesulfonic acid, the temperature is controlled at 40-60 ° C, and the reaction number is stirred. This process needs to be carefully monitored to prevent side reactions. After the reaction is completed, the target product can be obtained by extraction, column chromatography, etc.
Or another way can be used to couple 6-methyl-2-halopyridine with 4-methylphenylimidazole derivatives under the catalysis of base and transition metal according to the Ullman reaction mechanism. Potassium carbonate or sodium carbonate is selected as the base, copper salt or palladium salt is used as the catalyst, and the reaction is heated to 80-100 ° C in high boiling point solvents such as N, N-dimethylformamide. After the reaction, the product is purified by cooling, filtration, recrystallization and other operations.
These are all feasible ideas for the synthesis of 6-methyl-2- (4-methylphenyl) imidazolo [1,2-α] pyridine. When implementing, it is necessary to consider in detail the availability of raw materials, the convenience of reaction conditions and the requirements of product purity, and choose the optimal method.
What are the common specifications of 6-methyl-2- (4-methylphenyl) imidazo [1,2-alpha] pyridine on the market?
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-α] pyridine, this product is commonly used in the market, as detailed below.
Among the market, its specifications are other than purity. Common high-purity products can reach more than 98% purity. Such products are mostly used in precision experiments of scientific research. Because of the rarity of impurities, the experimental results can be guaranteed to be accurate. When researchers explore the characteristics of substances and reaction mechanisms, they have strict requirements for purity, and this high-purity specification is just what they need.
There are also those who are divided by the amount of packaging. Small packages are usually of the genus of 1 gram and 5 grams. This type is suitable for initial exploratory experiments. Researchers want to initially explore its properties and try new reaction paths. A small amount of packaging can not only meet the needs of the experiment, but also save resources and reduce costs. The large packages have 100 grams, 500 grams or even 1 kilogram, which are mostly prepared for the pre-pilot trial of industrial production, or for enterprises with a large demand for the substance, which can meet the dosage of larger-scale experiments or production.
Furthermore, there are specifications according to the dosage form. It is often in the form of powder, which has good fluidity, is easy to weigh and mix, and in many synthetic reactions, it is convenient to mix with other reagents evenly, promoting the smooth progress of the reaction. There are also solutions made in different concentrations, which are convenient to use directly and do not require further dissolution steps. In some processes that require high ease of operation, such as the preparation of specific pharmaceutical intermediates, the advantages of solution dosage forms are obvious.
In summary, 6-methyl-2- (4-methylphenyl) imidazolo [1,2-α] pyridine has a wide range of specifications in the market, each of which is suitable for different needs.