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What is the chemical structure of 6-METHYL-2- (4-METHYLPHENYL) IMIDAZO [1,2-A] PYRIDINE-3-ACETIC ACID
This is the chemical structure analysis of 6-methyl-2- (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid.
Looking at its name, it can be seen that this compound is composed of many parts. "6-methyl" means that the 6-carbon of the imidazolo [1,2-a] pyridine parent nucleus is connected with a methyl group. In the case of methyl, the group formed by one carbon and three hydrogens is also.
"2 - (4-methylphenyl) " means that the 2-carbon of the parent nucleus is connected to a phenyl group, and the 4-carbon of the phenyl group is connected with a methyl group. The phenyl group is a cyclic structure composed of six carbons, with a conjugated π electronic system.
"Imidazolo [1,2-a] pyridine", this is the parent nucleus structure. The imidazole ring fuses with the pyridine ring in a specific way to form this parent nucleus. The imidazole ring consists of two nitrogen atoms and three carbon atoms to form a five-membered heterocycle, and the pyridine ring is a six-membered heterocycle containing one nitrogen atom. After fusing, the two form a unique spatial structure and electron cloud distribution.
"3-acetic acid", indicating that the 3-position carbon of the parent nucleus is connected to an acetic acid group. The acetate group is a one-carbon group with a carboxyl group and a methyl group. The carboxyl group is a group composed of one carbon, two oxides and one hydrogen, which is acidic.
In summary, the chemical structure of this compound is composed of imidazolo [1,2-a] pyridine parent nucleus as the core, and methyl, 4-methylphenyl and acetic acid groups are connected at the 6th, 2nd and 3rd positions respectively. Each part is connected to each other to form a unique chemical structure. The complexity of its structure determines that it may have diverse chemical properties and biological activities.
What are the physical properties of 6-METHYL-2- (4-METHYLPHENYL) IMIDAZO [1,2-A] PYRIDINE-3-ACETIC ACID
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid, this is an organic compound. Its physical properties are unique, let me tell them one by one.
Looking at its properties, under normal circumstances, it may be a white to off-white solid powder. This appearance characteristic is quite common in many organic compounds, just like many finely carved powdered treasures, quietly exuding unique chemical charm.
When it comes to melting point, the melting point of this compound is a key indicator to determine its purity and characteristics. However, the exact melting point value often varies due to differences in preparation process and purity. Roughly speaking, its melting point is within a certain temperature range, which is like a precise threshold. At this temperature, the state of matter will quietly change.
In terms of solubility, it varies in organic solvents. In common organic solvents, such as ethanol, dichloromethane, etc., it may have a certain solubility. Ethanol, like a mild solvent messenger, can interact with the molecules of the compound, causing some molecules to integrate into it to form a uniform dispersion system; dichloromethane, also with its own unique molecular structure, exhibits a certain solubility to the compound. However, in water, its solubility may be low, and the polarity of water interacts with the molecular structure of the compound limited, making it difficult to accept a large number of molecules of this compound, as if there is a natural barrier between the two.
Furthermore, its density is also an important physical property. Although the exact density value needs to be accurately determined experimentally, it can be inferred that its density is equivalent to that of common organic compounds. In the world of chemical substances, under specific conditions, it interacts with surrounding substances according to its own density laws.
The physical properties of this compound are of great significance in chemical research and industrial applications. Only by understanding its properties, melting point, solubility and density can it be better controlled and applied, and it can be used in organic synthesis, drug development and other fields, such as right-hand assistants, to play a unique value.
6-METHYL-2- (4-METHYLPHENYL) IMIDAZO [1,2-A] PYRIDINE-3-ACETIC What is the main use of ACID
6-Methyl-2 - (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid, which is an organic compound. Under the paradigm of "Tiangong Kaiwu", although "Tiangong Kaiwu" does not directly deal with this substance, it can be deduced from its modern application.
In the field of medicinal chemistry, it may be an important pharmaceutical intermediate. Because organic compounds are often the cornerstones of synthetic drugs, through delicate chemical transformation, drugs with specific pharmacological activities can be prepared to treat various diseases. For example, in the development of small molecule drugs targeting specific disease targets, such compounds containing special structures can interact with biomacromolecules by virtue of their unique chemical structures, or be lead compounds that can be optimized and modified to become effective therapeutic drugs.
In the field of materials science, it may have potential applications. For example, the preparation of organic synthetic materials may endow the materials with special properties such as optical and electrical properties due to their structural properties. Taking the preparation of functional polymers as an example, introducing this compound into the polymer structure may improve the solubility and stability of the polymer, or even endow it with unique response properties for the development of smart materials.
In the field of fine chemicals, or as a synthetic raw material for special chemicals. Fine chemical products pursue high purity and high performance. The special structure of this compound can meet the synthesis needs of specific fine chemicals, and is used to prepare high-end coatings, fragrances, additives, etc., to improve the quality and performance of products. It has important uses in modern chemistry-related fields, or in drug research and development, material creation, and preparation of fine chemical products. Although it is not a product of Tiangong Kaiwu at that time, it shows a wide range of application prospects according to the development of modern science.
What are the synthesis methods of 6-METHYL-2- (4-METHYLPHENYL) IMIDAZO [1,2-A] PYRIDINE-3-ACETIC ACID
The synthesis method of 6-methyl-2- (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid covers various pathways. The synthesis of this compound can follow the common way of organic synthesis, starting with basic organic compounds, and gradually building the structure of the target molecule through various reactions.
First look at the selection of starting materials, or choose simple compounds containing pyridine and imidazole structures, or compounds with methyl, phenyl and other substituents as starting materials. Based on the starting material, various reactions can be applied to form the target product.
One, or nucleophilic substitution reaction can be used. In this reaction, a compound with a suitable leaving group acts with a nucleophilic reagent. For example, a pyridine derivative containing a halogen atom and a nucleophilic reagent containing an imidazole structure, under suitable conditions, the halogen atom is replaced by a nucleophilic reagent to initially establish a partial structure of imidazolopyridine. This step requires careful regulation of reaction conditions, such as temperature, solvent and base dosage, to increase the selectivity and yield of the reaction.
Second, the arylation reaction is also the key. React with an arylating reagent containing methylphenyl with a preliminarily constructed imidazolopyridine intermediate. Through the catalysis of transition metals, such as the aromatization reaction catalyzed by palladium, the methyl phenyl group is connected to the imidazolopyridine structure, and the key skeleton of the target molecule is precisely constructed. In this process, the type of catalyst, the selection of ligands, and the control of the reaction atmosphere all have a great impact on the reaction effect.
Furthermore, the molecular carbon chain is constructed to form the acetic acid part, or the carboxylation reaction can be used. Take an intermediate with an appropriate functional group and react with carboxylation reagents such as carbon dioxide under specific conditions to introduce the acetic acid structure. This step may require a special catalyst and reaction environment to ensure the smooth progress of carboxylation.
After each step of the reaction, the product often needs to be separated and purified. High purity 6-methyl-2- (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid can be obtained by means of column chromatography and recrystallization. Every step of this synthesis requires careful consideration and operation to achieve satisfactory synthetic results.
What is the market outlook for 6-METHYL-2- (4-METHYLPHENYL) IMIDAZO [1,2-A] PYRIDINE-3-ACETIC ACID
6-Methyl-2- (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid, this compound has broad prospects in the field of medicine and chemical industry.
Looking at today's market, the demand for innovative small molecule compounds in pharmaceutical research and development is like a thirsty earth. This compound has a unique structure and is like a delicate key, which may open the door to specific biological targets and emerge in the creation of new drugs. It has great potential in the development of drugs for neurological diseases. As some studies have shown, similar structural compounds have a positive effect on neurotransmitter regulation. 6-methyl-2 - (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid may contribute to the development of drugs for intractable neurological diseases such as epilepsy and Parkinson's disease.
Furthermore, there is also hope in the field of tumor therapeutic drugs. Now there is an urgent need for tumor treatment, and the development of targeted drugs is in full swing. This compound's unique chemical structure may give it the ability to target specific molecular pathways in tumor cells, making it a sharp edge to overcome tumor problems and bringing good news to many patients.
In the chemical industry, it may be used as a key intermediate in organic synthesis. For example, through a series of chemical reactions, more complex and special properties of organic materials can be constructed, which can be used in high-end material manufacturing to improve material properties and meet the needs of frontier fields such as aerospace and electronic technology.
However, its market development is not smooth sailing. R & D costs are high, such as new drug research and development requires multiple rounds of experiments, massive investment of funds and manpower. And competition is intense, with global scientific research institutions and pharmaceutical companies all investing in related fields. However, opportunities and challenges coexist. Over time, after unremitting research by researchers, 6-methyl-2- (4-methylphenyl) imidazolo [1,2-a] pyridine-3-acetic acid may be able to bloom in the market, injecting majestic impetus into the development of the pharmaceutical and chemical industry.