6 Methoxyimidazo 1 2 A Pyridine 2 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

6-Methoxyimidazo[1,2-a]pyridine-2-carboxylic acid

    Specifications

    HS Code

    190639

    Chemical Formula C9H8N2O3
    Molecular Weight 192.17
    Appearance Solid (usually white to off - white powder)
    Physical State At Room Temperature Solid
    Melting Point Specific value would require experimental determination
    Solubility In Water Low solubility, likely sparingly soluble
    Solubility In Organic Solvents May be soluble in some polar organic solvents like DMSO, DMF
    Pka Value related to the acidic carboxylic acid group, needs experimental determination
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents
    Odor Odorless or very faint odor

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    General Information
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    Frequently Asked Questions

    As a leading 6-Methoxyimidazo[1,2-a]pyridine-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 6-Methoxyimidazo [1,2-a] pyridine-2-carboxylic acid
    6-Methoxy imidazolo [1,2-a] pyridine-2-carboxylic acid, its chemical structure is formed by combining the parent nuclear structure of imidazolo [1,2-a] pyridine with a specific substituent.
    Looking at its parent nucleus, the structure of imidazolo [1,2-a] pyridine is fused by an imidazole ring and a pyridine ring. This fusing method endows the compound with unique spatial configuration and electronic properties. Among them, the imidazole ring is composed of two nitrogen atoms and three carbon atoms to form a five-membered heterocycle, and the pyridine ring is a six-membered heterocycle containing one nitrogen atom. The two are connected by specific atoms to form a stable and special fused ring system.
    Looking at the substituent, on the basis of the imidazolo [1,2-a] pyridine parent nucleus, the methoxy group (-OCH) is connected at position 6. The oxygen atom in this methoxy group affects the electron cloud distribution of the parent nucleus by virtue of its lone pair electrons, thereby changing the electronic properties and steric resistance of the compound. At the same time, the carboxyl group (-COOH) is connected at position 2, and the carboxyl group is acidic and can participate in many chemical reactions, such as acid-base neutralization. The existence of this carboxyl group greatly enriches the chemical activity and reactivity of the compound.
    In summary, the chemical structure of 6-methoxyimidazo [1,2-a] pyridine-2-carboxylic acid is the product of the ingenious combination of the parent nucleus imidazo [1,2-a] pyridine with the methoxy group at position 6 and the carboxyl group at position 2. This unique structure endows the compound with special physical and chemical properties and potential biological activities.
    What are the main uses of 6-Methoxyimidazo [1,2-a] pyridine-2-carboxylic acid
    6-Methoxyimidazolo [1,2-a] pyridine-2-carboxylic acid, an organic compound. It has a wide range of uses and is often a key intermediate in drug development in the field of medicinal chemistry. By ingeniously modifying and modifying its chemical structure, new drug molecules with specific pharmacological activities can be created. For example, some compounds with potential antibacterial, anti-inflammatory or anti-tumor effects may be carefully synthesized from this as a starting material.
    In the field of materials science, the preparation of some functional materials may also use this substance. Due to its unique molecular structure and chemical properties, it may endow materials with specific optical, electrical or mechanical properties, such as in organic optoelectronic materials, or affect the charge transport and luminous efficiency of materials.
    In the field of chemical synthesis, it is an important cornerstone for the construction of more complex organic molecular structures. With its carboxyl and methoxy active functional groups, it can be combined with other organic compounds through various chemical reactions, such as esterification, amidation, nucleophilic substitution, etc., to expand the route of organic synthesis and synthesize organic compounds with rich structures and different functions.
    What are the synthesis methods of 6-Methoxyimidazo [1,2-a] pyridine-2-carboxylic acid
    The synthesis method of 6-methoxy imidazolo [1,2-a] pyridine-2-carboxylic acid has a variety of paths to follow. One of the common ones is to use an appropriate pyridine derivative as the starting material. The methoxy group is introduced at a specific position of the pyridine ring before the specific position of the pyridine ring. This step often requires the use of nucleophilic substitution reaction, the selection of appropriate methoxylation reagents, and the methoxy group is successfully connected under suitable reaction conditions, such as a specific temperature and the presence of a base catalyst.
    Then, the structure of imidazolo [1,2-a] pyridine is constructed by cyclization reaction. This cyclization process, or by means of condensation reaction, selects the reagent that can promote the formation of intramolecular rings, and the reaction conditions need to be carefully adjusted to ensure the high efficiency and accuracy of cyclization.
    Furthermore, carboxyl groups are introduced into the imidazolo [1,2-a] pyridine structure obtained. This can be achieved in various ways, such as using halogenated alkyl carboxylic acid esters as reagents, nucleophilic substitution, and then hydrolysis to convert the ester groups into carboxylic groups. The hydrolysis step depends on the characteristics of the reagents and substrates used, and the conditions of acid catalysis or base catalysis are selected to obtain the target 6-methoxy imidazolo [1,2-a] pyridine-2-carboxylic acid. < Br >
    There are also those who start with other heterocyclic compounds and construct the target structure through multi-step functional group transformation and cyclization. The initial heterocyclic ring is modified first, and the functional group that can be further reacted is introduced, and then the imidazolo [1,2-a] pyridine structure is gradually constructed through multi-step reaction, and finally the carboxyl group is introduced. The reaction conditions and the selection of reagents must be carefully considered in each step to ensure the feasibility and yield of the synthetic route.
    What are the physical properties of 6-Methoxyimidazo [1,2-a] pyridine-2-carboxylic acid
    6-Methoxyimidazolo [1,2-a] pyridine-2-carboxylic acid is one of the organic compounds. It has unique physical properties and has attracted much attention in the fields of scientific research and chemical industry.
    Looking at its properties, it is mostly white to light yellow crystalline powder under normal conditions, which is easy to store and use, and also suggests the order of its molecular arrangement. Its melting point is about a specific range, which is crucial for the identification and purification of this compound. The accurate determination of the melting point can help determine its purity geometry.
    In terms of solubility, it has a certain solubility in organic solvents, such as common ethanol and dichloromethane. However, in water, the solubility is relatively limited. This property is closely related to the polarity of the molecule. In its molecular structure, the combination of methoxy, imidazolopyridine ring and carboxyl group creates a specific polar distribution, causing it to behave differently in different solvents. The characteristic of solubility is of great significance in the separation, purification and choice of reaction medium of the compound.
    Furthermore, the stability of this compound is also an important physical property. Under normal environmental conditions, it has a certain stability, and when exposed to extreme conditions such as strong acid, strong base or specific high temperature and light, the molecular structure may change. Understanding this stability can help to take appropriate protective measures during storage, transportation and use to maintain the stability of its chemical structure and properties. The physical properties of 6-methoxyimidazolo [1,2-a] pyridine-2-carboxylic acid lay the foundation for its application in many fields, whether it is used as a synthesis intermediate or for drug research and development.
    What is the price range of 6-Methoxyimidazo [1,2-a] pyridine-2-carboxylic acid in the market?
    6-Methoxyimidazolo [1,2-a] pyridine-2-carboxylic acid, which is in the market, its price domain is difficult to determine. The level of its price often varies due to various reasons.
    First, it is related to its quality. If the quality is good and pure, and impurities are rare, the price must be high; if the quality is impurities, the price should be low. Second, it depends on the state of supply and demand. If there are many applicants and few suppliers, the price will rise; if the supply exceeds the demand, the price will decline. Third, the difficulty of preparation is also involved. If the preparation method is complicated and expensive, the price will be high; if the preparation is simple, the cost is controllable, and the price is close to the people.
    Looking at the past, similar products, the price may range from a few to several hundred yuan per gram. However, 6-methoxyimidazolo [1,2-a] pyridine-2-carboxylic acid, depending on the use, or used in pharmaceutical research and development, or as a chemical raw material, the price is also different. For medical users, because it is related to health, the quality requirements are extremely strict, and the price is often high. For chemical users, the price may be slightly lower, but it also varies according to the specific situation.
    Therefore, if you want to know the exact price, you should carefully observe the current state of the market and consult the merchants to obtain a more accurate number. It is difficult to generalize the range of the price.