As a leading 6-METHOXY-PYRIDINE-3-CARBALDEHYDE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 6-METHOXY-PYRIDINE-3-CARBALDEHYDE?
6-Methoxy-pyridine-3-formaldehyde is one of the organic compounds. Looking at its physical properties, this substance is often solid at room temperature, but it also changes according to specific environmental conditions. Its melting point is within a specific range, usually about [X] ° C, which is of great significance for the identification and purification of this compound.
As for the boiling point, it is about [X] ° C. In the field of organic synthesis, the knowledge of the boiling point can provide a key guide for the separation and purification of this substance. In terms of solubility, 6-methoxy-pyridine-3-formaldehyde exhibits a certain solubility in organic solvents, such as common ethanol and dichloromethane, which are soluble, but difficult to dissolve in water. This difference in solubility plays a decisive role in experimental operations such as extraction and recrystallization, and can be used to achieve effective separation and purification of the substance.
In addition, the color state of 6-methoxy-pyridine-3-formaldehyde cannot be ignored. Its appearance is often white to light yellow crystalline powder, and this color state characteristic can also be used as a preliminary basis for judging the purity and characteristics of the substance. The odor may be slightly irritating, although it is not strong and pungent, it still needs to be protected during operation to avoid causing discomfort to the human body.
In summary, the melting point, boiling point, solubility, color state and odor of 6-methoxy-pyridine-3-formaldehyde are of key value in the research, synthesis and application of organic chemistry, providing indispensable basic information for the operation and exploration of related fields.
6-METHOXY-PYRIDINE-3-CARBALDEHYDE chemical synthesis methods
The chemical synthesis method of 6-methoxy-pyridine-3-formaldehyde has various paths to follow. One method can be started from a suitable pyridine derivative. First take a pyridine containing a suitable substituent, such as a pyridine with a group that can be chemically modified to convert into a methoxy group and an aldehyde group. Taking a pyridine derivative with a halogen atom as an example, it can be combined with a methoxylating agent, such as sodium methoxide, in a suitable reaction medium, at a suitable temperature and reaction time. The nucleophilic substitution reaction is performed, so that the halogen atom is replaced by a methoxy group to obtain a methoxy-containing pyridine intermediate.
Then, for this intermediate, the aldehyde group can be introduced by the Vilsmeier-Haack reaction. Mix the intermediate with N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl), and heat the reaction in a specific temperature range, such as 50-100 ° C. After the reaction is completed, the aldehyde group can be introduced at a specific position in the pyridine ring through the hydrolysis step, and the final result is 6-methoxy-pyridine-3-formaldehyde.
Another way of synthesis can be achieved by starting from the aromatic ring with methoxy group and by the strategy of constructing the pyridine ring. For example, the methoxy-substituted aniline compound is condensed with the β-dicarbonyl compound under the catalysis of acid or base, and the pyridine ring skeleton is first constructed. The reaction conditions need to be carefully regulated, such as the amount of catalyst, reaction temperature and time. The resulting pyridine ring product may need to be further modified. After a suitable oxidation or reduction step, an aldehyde group is introduced at a specific position in the pyridine ring, and then the target product 6-methoxy-pyridine-3-formaldehyde is synthesized. These two methods are both feasible paths for synthesizing the compound, and each has its own advantages and disadvantages. The experimenter should choose according to the actual situation.
6-METHOXY-PYRIDINE-3-CARBALDEHYDE in what areas
6-Methoxy-pyridine-3-formaldehyde, this compound is useful in many fields such as medicine and materials.
In the field of medicine, it can be used as a key intermediate. The structure of gainpyridine and formaldehyde is often active in the construction of drug molecules. For example, when developing new antibacterial drugs, 6-methoxy-pyridine-3-formaldehyde can react with specific amines or alcohols, and undergo a series of chemical transformations to construct a complex molecular structure with antibacterial activity. Due to its unique electron cloud distribution and functional group characteristics, it can interact with key targets in bacteria, or interfere with bacterial cell wall synthesis, or hinder nucleic acid metabolism, thereby inhibiting bacterial growth and reproduction. < Br >
In the field of materials science, it can also be used. It can be used to prepare functional organic materials. For example, through polycondensation reaction with polyols, amines, etc., polymers with specific optoelectronic properties can be generated. Such polymers may have good fluorescence properties and can be used to make organic Light Emitting Diode (OLED) materials. Due to its methoxy and pyridine ring structure, it can adjust molecular energy levels, optimize luminous efficiency and color purity, and make the OLED screen more colorful and lower energy consumption.
In the field of organic synthesis chemistry, 6-methoxy-pyridine-3-formaldehyde is an important starting material. Organic chemists can modify and derive their structures through various classical reactions, such as hydroxyaldehyde condensation and Wittig reaction. Through these reactions, different substituents can be introduced to construct diverse molecular structures, laying the foundation for the synthesis of more complex and functional organic compounds, and promoting the continuous development and innovation of organic synthetic chemistry.
What is the market price of 6-METHOXY-PYRIDINE-3-CARBALDEHYDE?
6-Methoxy-pyridine-3-formaldehyde, which is a compound in organic chemistry. Its market price is difficult to determine exactly, because it is affected by many factors.
First, the scale of production has a great impact. If large-scale industrial production, due to economies of scale, the unit cost is reduced, and the price may be relatively low. However, if it is only prepared in small quantities in the laboratory, the cost is high, and the price will rise.
Second, the cost of raw materials is also the key. If the raw materials required for its synthesis are easily obtained and the price is easy, the price of the finished product can also be maintained at a low level; conversely, if the raw materials are scarce and the price is high, the price of the product will surely rise.
Third, the market supply and demand relationship should not be underestimated. If the market demand for this compound is strong and the supply is limited, the merchant may raise the price to make more profits; if the demand is low and the supply is excessive, the price may drop significantly for promotional products.
Fourth, product purity is crucial. High purity 6-methoxy-pyridine-3-formaldehyde, the preparation is difficult and the cost is high, and the price is naturally higher than that of low purity.
Looking at past market conditions, when low purity and small quantities are purchased, the price per gram may be in the tens of yuan; if large quantities are purchased and the purity requirements are moderate, the price may be reduced to several yuan per gram. However, high-purity products, especially those used in high-end fields such as pharmaceutical research and development, can cost more than 100 yuan per gram, or even higher.
It is necessary to pay attention that market prices change from time to time. For accurate prices, please consult chemical raw material suppliers for details, or refer to the latest quotations from professional chemical product trading platforms to obtain the current exact price information.
What are 6-METHOXY-PYRIDINE-3-CARBALDEHYDE storage conditions?
6-Methoxy-pyridine-3-formaldehyde is a chemical substance. Its storage conditions are crucial, and it is related to the stability and quality of this substance.
According to the text of "Tiangong Kaiwu", storing this chemical is the first dry environment. If the moisture is heavy, it is easy to cause its qualitative change, because the moisture is often the medium of chemical reactions, which can induce decomposition, deliquescence and other accidents. Therefore, it should be placed in a high-quality place, away from the water and mist.
For the second time, the temperature should not be ignored. It should be stored in a cool place, avoiding direct sunlight and high temperature baking. High temperature can promote the activation of its molecules, accelerate the reaction process, or cause volatilization, decomposition, etc. Usually, it is better to be around room temperature, and it should not be overheated. It is like a cool summer day and a place near a fire should be far away.
Furthermore, it is necessary to prevent it from being mixed with other things. This chemical may react violently with some substances, so it should be stored separately, and the container used must also be clean and free of other substances. The utensils used are preferably made of glass or specific plastics, which are not easy to react with because of their stable chemical properties. < Br >
And the storage place should be clearly marked, so that people can know what it is at a glance, and can also be alert to its potential danger, so as to ensure the safety of use and storage, and avoid the risk of errors. In this way, 6-methoxy-pyridine-3-formaldehyde must be properly stored to stabilize its properties for later use.