6 Methoxy 2 Methyl 3 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

6-methoxy-2-methyl-3-nitropyridine

    Specifications

    HS Code

    748312

    Chemical Formula C7H8N2O3
    Appearance Solid (usually)
    Melting Point Data - specific value needed from literature
    Boiling Point Data - specific value needed from literature
    Solubility In Water Low (organic nitro - pyridine derivatives generally have low water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Density Data - specific value needed from literature
    Pka Data - specific value needed from literature

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 6-methoxy-2-methyl-3-nitropyridine?
    6-Methoxy-2-methyl-3-nitropyridine, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of pharmaceutical synthesis. It can construct complex molecular structures with biological activity through specific chemical reaction steps to assist in the development of new drugs, such as the synthesis of pyridine drugs with unique pharmacological effects.
    In the field of pesticides, it also has important functions. It can be used as a raw material to prepare some highly efficient, low-toxic and environmentally friendly pesticide varieties. With its special chemical structure, pesticides are endowed with unique insecticidal, bactericidal or herbicidal properties, providing an effective means for pest control and weed control in agricultural production.
    In the field of materials science, 6-methoxy-2-methyl-3-nitropyridine can also play a role. It can participate in the synthesis of functional materials. Through chemical modification and polymerization, the materials are endowed with special properties such as electrical conductivity and optical activity, which contribute to the creation of new materials.
    In addition, as a typical pyridine derivative in the basic research of organic synthetic chemistry, it provides an ideal model compound for exploring chemical reaction mechanisms and studying molecular interactions, and promotes the theoretical development and technological innovation of organic chemistry. Overall, 6-methoxy-2-methyl-3-nitropyridine has significant value and applications in many fields.
    What are 6-methoxy-2-methyl-3-nitropyridine synthesis methods?
    The synthesis method of 6-methoxy-2-methyl-3-nitropyridine is a key issue in the field of organic synthesis. Its synthesis path is like exploring a labyrinth, which requires careful planning and step by step.
    One of the common synthesis methods can be obtained from 2-methyl-3-nitropyridine through methoxylation. In this process, suitable methoxylation reagents, such as dimethyl sulfate, iodomethane, etc., need to be selected under basic conditions to undergo nucleophilic substitution reaction with 2-methyl-3-nitropyridine. The choice of base is also crucial, such as potassium carbonate, sodium carbonate, etc. The concentration, dosage, reaction temperature, time and other factors have a significant impact on the yield and selectivity of the reaction.
    Second, you can start with 6-methoxy-2-methylpyridine and introduce nitro groups through nitrification. Nitrification reagents often choose a mixed acid system of nitric acid and sulfuric acid. This reaction requires strict control of the reaction conditions, because the nitrification reaction is dangerous, and the reaction selectivity needs to be fine-tuned. If the temperature is too high, it is easy to cause the formation of polynitrification products, which affects the purity of the target product; if the temperature is too low, the reaction rate is slow and takes too long.
    In addition, there is a strategy to use pyridine as the starting material and introduce methoxy, methyl and nitro groups in sequence. Although this path is slightly complicated, the reaction conditions of each step are relatively mild and easier to control. For example, pyridine is used as the substrate, methoxy is introduced under suitable conditions, and then methyl is introduced through methylation reaction, and finally the target product 6-methoxy-2-methyl-3-nitropyridine is obtained through nitration reaction.
    The synthesis process, such as craftsmen carving beautiful jade, requires careful control at each step, and the reaction conditions are related and influenced by each other. Only through in-depth understanding of the reaction mechanism and precise regulation of conditions can 6-methoxy-2-methyl-3-nitropyridine be synthesized efficiently and with high purity, laying a solid foundation for subsequent research and application.
    What are the physical properties of 6-methoxy-2-methyl-3-nitropyridine?
    6-Methoxy-2-methyl-3-nitropyridine is a kind of organic compound. The physical properties of this compound are particularly well studied by us.
    Its properties are mostly solid at room temperature and pressure. Looking at its color, or white-like powder, it has a fine texture, which is caused by the orderly arrangement of molecular structures and the scattering of light.
    When it comes to the melting point, it is about a specific temperature range. Due to the intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., which restrict each other, a certain amount of heat energy is required to break its lattice and turn the solid state into a liquid state. When heated to the melting point, the molecule is energized, the vibration intensifies, and the lattice gradually collapses, resulting in a liquid state.
    The boiling point also has corresponding values. At the boiling point, the molecular kinetic energy inside the liquid increases greatly, which is enough to overcome the external pressure and the attractive force between molecules, escape from the liquid surface, and form a gaseous state. This temperature reflects the difficulty of the molecule breaking free from the liquid phase binding, which is closely related to the intermolecular force and molecular weight.
    In terms of solubility, it may have a certain solubility in organic solvents, such as ethanol and acetone. Due to the similar miscibility principle, some structures of the compound are similar to the polarity of organic solvents, and they can interact with each other with intermolecular forces, so they are soluble. However, in water, its molecular polarity is quite different from that of water, and its solubility may be very small.
    Density is also one of its important physical properties. The value of its density is related to the mass of the molecule and the degree of packing compactness. A larger density indicates that the molecular mass is larger and closely arranged, and the number of molecules contained in the unit volume is more.
    In summary, the physical properties of 6-methoxy-2-methyl-3-nitropyridine are determined by its molecular structure. All properties are related and are of great significance in chemical research and practical applications.
    What are the chemical properties of 6-methoxy-2-methyl-3-nitropyridine?
    6-Methoxy-2-methyl-3-nitropyridine is one of the organic compounds. Its chemical properties are unique and worth exploring.
    This compound contains functional groups such as methoxy, methyl and nitro. Methoxy (-OCH 🥰) has a donator effect, which can increase the electron cloud density of the pyridine ring and has a significant impact on its reactivity. Due to the characteristics of the donator, the electron cloud density of the pyridine ring can be relatively increased, and it is easier to react in the adjacent and para-sites during the electrophilic substitution reaction. < Br >
    Methyl (-CH) is also a supply chain group. Although the supply chain is weaker than methoxy, it can also increase the electron cloud density of the pyridine ring, and it has an effect on the selectivity of the reaction check point due to the steric hindrance effect. For example, in some reactions, the presence of methyl groups will prevent the reagent from approaching a specific location, thereby changing the reaction path and product distribution.
    Nitro (-NO ²) is a strong electron-absorbing group, which greatly reduces the electron cloud density of the pyridine ring, making the pyridine ring more prone to nucleophilic substitution reactions. Under appropriate conditions, nucleophiles are prone to attack the positions with low electron cloud density on the pyridine ring. At the same time, nitro groups can also participate in some special reactions, such as the reduction reaction of nitro groups, which can be converted into other functional groups such as amino groups, expanding the reaction path and derivation possibilities of compounds.
    6-methoxy-2-methyl-3-nitropyridine exhibits unique chemical activity and reaction selectivity due to the joint action of these functional groups, and is widely used in the field of organic synthesis. It can be used as an intermediate to participate in the construction of a variety of complex organic compounds.
    What is the price of 6-methoxy-2-methyl-3-nitropyridine in the market?
    6-Methoxy-2-methyl-3-nitropyridine is in the market, and its price is difficult to determine. The price of this chemical often changes due to many reasons.
    First, the supply and demand situation has a huge impact on the price. If there are many people in the market, but the supply is small, the price will be high; conversely, if the supply exceeds the demand, the price may decline.
    Second, the cost of production is also important. The price of raw materials, the method of preparation, and the cost of energy consumption are all related to the cost. If the price of raw materials is high, or the preparation requires multiplication and energy consumption, the price will also increase.
    Third, the purity of the product also affects its price. The higher the purity, the more difficult it is to prepare, and the more expensive the price.
    Fourth, the region of the seller and the buyer also has an impact. The difference in transportation fees and taxes can vary.
    Although "Tiangong Kaiwu" is detailed in various process products, this chemical is not owned when it was written, so it is difficult to know its price. If you want to know the exact price of 6-methoxy-2-methyl-3-nitropyridine, you must consult all chemical raw material suppliers or check it on the chemical trading platform before you can get a near-real price.