6-Mercapto-3-pyridine carboxlic acid

6-Mercapto-3-pyridinecarboxylic acid is an organic compound. It has unique chemical properties.
This compound contains thiol (-SH) and pyridinecarboxylic acid structures. The thiol group is active and easy to participate in chemical reactions. In case of oxidants, it can be oxidized to disulfide bonds (-S-S-), which is of great significance in the field of chemical modification and cross-linking of proteins and peptides.
The pyridine ring is aromatic and basic, and the nitrogen atom can accept protons, so that the compound can form salts in acidic environments. The pyridine ring is also an active checking point for nucleophilic substitution reactions, and can react with a variety of electrophilic reagents, providing the possibility for the construction of complex organic molecules.
Carboxyl group (-COOH) is acidic, can ionize hydrogen ions, and has the general property of acid. It can react with bases to form salts and water, and esterify with alcohols to form ester compounds.
6-mercapto-3-picolinocarboxylic acid is widely used in pharmaceutical chemistry, materials science, organic synthesis chemistry and other fields due to these chemical properties. In the field of medicine, or can be used as a pharmaceutical intermediate to construct molecules with specific biological activities; in materials science, or can participate in the preparation of functional materials with special properties.

6-Mercapto-3-pyridinecarboxylic acid, an organic compound, has important uses in many fields.
In the field of medicine, its role is quite large. It can be used as a key intermediate in drug synthesis. The unique chemical structure of Gainpyridine and thiol groups endows the substance with special chemical and biological activities. Through specific chemical reactions, it can be integrated into the molecular structure of the drug to improve the properties of the drug. For example, it can enhance the affinity of the drug to specific targets, so that the drug can act more precisely on diseased cells, thereby enhancing the efficacy of the drug. Or optimize the metabolic kinetic properties of the drug, such as prolonging the action time of the drug in the body, reducing the frequency of administration, and improving the compliance of patients.
In the field of materials science, 6-mercapto-3-pyridinecarboxylic acid is also useful. It can be used to prepare functional materials. Due to the coordination of thiol groups with a variety of metal ions, it can be used to prepare metal-organic framework materials (MOFs). Such materials have the characteristics of high specific surface area, adjustable pore structure, etc., and show excellent performance in gas adsorption and separation, catalysis, etc. For example, in gas adsorption, it has the ability to selectively adsorb specific gas molecules, which can be used to efficiently separate target gases from mixed gases; in catalytic reactions, it can provide rich activity check points for reactions, speed up the reaction rate, and improve the reaction efficiency.
In the field of chemical research, it is an important chemical reagent. It is often used in the study of organic synthesis reactions. As a reactant, it participates in various organic reactions to explore new reaction paths and methods. Chemists can control the reaction conditions to achieve precise regulation of the structure and properties of reaction products, providing new ideas and methods for the development of organic synthetic chemistry, and promoting the continuous development of chemistry.
In summary, 6-mercapto-3-pyridinecarboxylic acid plays an indispensable role in many fields such as medicine, materials science, and chemical research, and has made significant contributions to the progress and development of related fields.

The synthesis method of 6-mercapto-3-pyridinecarboxylic acid has been known for a long time and has various routes. The following is a detailed description of Jun.
First, the pyridine derivative is used as the starting material. First, take a suitable pyridine compound with a modifiable group in a specific position in its structure. The carboxyl group is introduced at the third position of the pyridine ring by a delicate chemical reaction. The introduction of this carboxyl group often requires the help of specific reagents and suitable reaction conditions. For example, a carboxylation-capable reagent can be selected to react with the pyridine compound at the appropriate temperature, pressure and catalyst to achieve the successful access of the 3-position carboxyl group. < Br >
Then, the thiol group is introduced at the 6-position of the pyridine ring. This process also requires careful selection of reagents and conditions. The common method is to use a thiol-containing reagent to interact with a carboxyl-containing pyridine derivative in a mild and controlled reaction environment to successfully connect the thiol group to the 6-position. This step requires attention to the selectivity and yield of the reaction to ensure that the thiol group is precisely connected without affecting the formed carboxyl group.
Second, other nitrogen-containing heterocyclic compounds are used as the starting point. First, the heterocyclic ring is modified, and the structure of the pyridine ring is gradually constructed through a series of chemical reactions. During the construction of the pyridine ring, carboxyl groups and thiol groups are introduced synchronously or sequentially. For example, the activity check point on the heterocyclic ring can be used to introduce the carboxyl-related substituent first, and then converted into the carboxyl group through the reaction. Subsequently, the thiol group is introduced at the 6 position of the pyridine ring through a specific thiogylation reaction. Although this path is more complex, it can provide higher selectivity and better reaction yield in some specific cases.
Third, there is also a method of biosynthesis. With the help of specific microorganisms or enzymes, using natural substrates as raw materials, 6-mercapto-3-pyridinecarboxylic acid is generated through the metabolic pathway in the microorganism or the catalytic reaction of enzymes. This biosynthesis method has the advantages of green and environmental protection, and the reaction conditions are mild. However, the screening and culture requirements for microorganisms or enzymes are rather high, and it is necessary to precisely control the environmental factors of the reaction, such as temperature, pH value, etc., to ensure the smooth progress of the biocatalytic reaction and the generation of products.

6-Mercapto-3-pyridinecarboxylic acid, the price between cities, it is difficult to determine a definite number. The change in its price depends on multiple ends. In the market of this compound, the balance between supply and demand is the main factor. If there is a demand for prosperity and a lack of supply, the price will rise; if there is an oversupply, the price may drop.
Its preparation also affects its price. If the preparation method is complex, if the materials used are extravagant, the labor cost will increase, and the price will also increase. On the contrary, if the preparation is easy and the materials used are saved, the price may decrease.
Furthermore, the quality of its superiority is also related to the price.
And the competition in the market is also a variable of price. Merchants compete to sell, or to occupy the market, if there is a profit to ask for quantity, the price is also affected by it.
According to the view of "Tiangong Kaiwu", the price of a product is determined by all conditions. For 6-mercapto-3-pyridinecarboxylic acid, the current price is about a few yuan to tens of yuan per gram. However, this is only a rough estimate. The actual price should be based on the current market price. The market situation changes, and the price is difficult to maintain a constant number.

6-Mercapto-3-pyridine carboxylic acid (6-mercapto-3-pyridinecarboxylic acid) is one of the organic compounds. Its storage conditions are crucial to the stability and quality of this substance.
This substance should be stored in a cool and dry place. In a cool place, the temperature should be controlled within a moderate range and should not be too high. High temperature can easily cause chemical reactions in compounds, such as accelerating their decomposition and oxidation processes, which damage their structure and properties. A dry environment is also indispensable. Moisture can easily lead to moisture absorption or cause adverse changes such as hydrolysis, which affects its purity and properties.
Furthermore, the storage place should be well ventilated. Good ventilation can disperse harmful gases that may be generated, and can even the temperature and humidity in the storage space, avoiding local temperature and humidity abnormalities and endangering this substance.
The choice of storage container should not be underestimated. Choose the appropriate material to prevent reaction with the compound. Glass containers are usually preferred because of their stable chemical properties, which are inert to most compounds and are not easy to interact with. However, if the compound is aggressive to glass, other materials need to be selected, such as specific plastic materials, etc. Make sure that the container is tightly sealed to prevent air, moisture, etc. from invading.
And the storage place should be away from fire, heat and oxidants. 6 - Mercapto - 3 - pyridine carboxylic acid may burn or explode when exposed to open flames, hot topics or contact with oxidants, endangering safety. Therefore, proper storage locations and strict compliance with the above conditions can keep 6 - Mercapto - 3 - pyridine carboxylic acid long-term. Its inherent characteristics are required for scientific research and production.