6 Iodo 1 2 4 Triazolo 1 5 A Pyridine
pyridine pyrrole pyrazine piperidine piperazine

6-Iodo[1,2,4]triazolo[1,5-a]pyridine

    Specifications

    HS Code

    321617

    Chemical Formula C6H4IN3
    Molecular Weight 245.02 g/mol
    Appearance Solid (usually a white - off - white powder)
    Physical State At Room Temperature Solid
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy 6-Iodo[1,2,4]triazolo[1,5-a]pyridine in China?
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    Frequently Asked Questions

    As a leading 6-Iodo[1,2,4]triazolo[1,5-a]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 6-Iodo [1,2,4] triazolo [1,5-a] pyridine?
    6-Iodine [1,2,4] triazolo [1,5-a] pyridine, which is an organic compound. Its chemical structure is quite delicate. It is formed by fusing a pyridine ring with a [1,2,4] triazole ring, and iodine atoms are introduced at the 6 position of the pyridine ring.
    Pyridine ring is a nitrogen-containing six-membered heterocycle, which has aromatic properties. Its electron cloud distribution is unique, endowing the compound with certain stability and reactivity. [1,2,4] triazole ring is also aromatic. It consists of three nitrogen atoms and two carbon atoms to form a five-membered heterocycle. The presence of nitrogen atoms changes the density of the ring electron cloud, which affects the physical and chemical properties of the compound.
    The introduction of iodine atoms has a significant impact on the properties of the compound. Iodine atoms have a large atomic radius and electronegativity, which can enhance the van der Waals force between molecules and affect the physical properties of compounds such as melting point and boiling point. In chemical reactions, iodine atoms can be used as leaving groups to participate in nucleophilic substitution, coupling and other reactions, providing a way for the derivatization of compounds and expanding their applications in the field of organic synthesis.
    The structure of this compound determines its potential application in the fields of medicine, materials science and other fields. In the field of medicine, its structural properties may be used to design and synthesize drug molecules with specific biological activities; in the field of materials science, its unique electronic structure and molecular shape may endow materials with special optical and electrical properties.
    What are the main physical properties of 6-Iodo [1,2,4] triazolo [1,5-a] pyridine?
    6-Iodine [1,2,4] triazolo [1,5-a] pyridine is an organic compound. It has unique physical properties and is related to this substance, which are described in detail below.
    Looking at its appearance, at room temperature and pressure, 6-iodine [1,2,4] triazolo [1,5-a] pyridine is mostly solid, but its specific appearance may vary depending on the purity and crystallization conditions, or it is a white to light yellow crystalline powder. This appearance feature can help identify.
    Talking about the melting point, this is an important physical constant. However, the melting point data are often different due to different test methods, instruments and sample purity. In general, the specific melting point value can be obtained after precise determination, which is crucial for the identification and purification of the compound and can be used as a quality control index.
    In terms of solubility, the solubility of 6-iodine [1,2,4] triazolo [1,5-a] pyridine in organic solvents varies. In common organic solvents such as dichloromethane and chloroform, it may have a certain solubility, which is conducive to the separation, purification and reaction medium selection of reactants or products in organic synthesis reactions. In water, its solubility is low, because its structure contains hydrophobic groups, making it difficult to dissolve in the aqueous phase with strong polarity.
    In addition, the density of the compound is also one of the physical properties. Although the exact density value needs to be accurately determined by experiments, according to its structure and constituent elements, it can be inferred that its density may be in a similar range to that of similar structural compounds, which is of great significance for application scenarios involving mass and volume conversion.
    In summary, the physical properties of 6-iodine [1,2,4] triazolo [1,5-a] pyridine, such as appearance, melting point, solubility and density, play an important role in its synthesis, identification and application, and are of great importance to scientific researchers.
    What are the applications of 6-Iodo [1,2,4] triazolo [1,5-a] pyridine?
    6-Iodine [1,2,4] triazole [1,5-a] pyridine is useful in many fields. In the field of medicine, it may be a key raw material for the creation of new drugs. Due to its unique chemical structure, it can be combined with specific targets in organisms, so it may have great potential in the treatment of diseases. For example, it can be used to design and develop anti-tumor drugs, which can precisely act on specific proteins or signaling pathways of tumor cells to inhibit tumor growth and spread; or it can be used to develop antiviral agents to interfere with the replication mechanism of certain viruses, so as to achieve antiviral effect.
    In the field of materials science, this compound has also emerged. In the preparation of new functional materials, 6-iodine [1,2,4] triazolo [1,5-a] pyridine can be used as a construction unit to endow materials with unique photoelectric properties. For example, its introduction into organic semiconductor materials is expected to improve the charge transfer efficiency of materials, and play an important role in the manufacture of organic Light Emitting Diode (OLED), organic solar cells and other devices, so that the performance of the device can be optimized, such as improving the luminous efficiency and enhancing the photoelectric conversion efficiency of the battery.
    Furthermore, in the field of chemical synthesis, it is often used as a key intermediate. Due to its active checking point of structure, it can be derived through a variety of chemical reactions. Compounds with complex structures and specific functions can be derived. Chemists can use this to expand the compound library, lay the foundation for further research and application, and help develop more chemical products with excellent performance and unique functions.
    What are the synthesis methods of 6-Iodo [1,2,4] triazolo [1,5-a] pyridine?
    There are many ways to synthesize 6-iodine [1,2,4] triazolo [1,5-a] pyridine.
    First, the corresponding pyridine derivative can be started. First, the appropriate substituent is introduced into the specific position of the pyridine ring to activate the check point, which is convenient for subsequent reaction with iodine-containing reagents. It is common to use pyridine with suitable substituents as a substrate, and under specific catalysts and reaction conditions, an electrophilic substitution reaction occurs with an iodine source to introduce iodine atoms into the target position. In this process, the choice of catalysts is very critical, such as some metal salt catalysts, which can effectively promote the reaction. At the same time, the reaction temperature, reaction time and the proportion of reactants need to be precisely regulated to achieve the best reaction effect.
    Second, the triazolopyridine skeleton construction method can be used. First, the intermediate containing triazole and pyridine fragments is prepared, and the reaction route is reasonably designed to gradually connect the two and form a ring. At the same time, iodine atoms are introduced at the desired 6-position during the cyclization process or subsequent steps. For example, by using the cyclization reaction between nitrogen-containing heterocyclic compounds, the structure of triazolopyridine is constructed by selecting suitable reaction reagents and conditions, and then the iodine atoms are introduced into the 6-position through halogenation reaction. This path requires careful optimization of the cyclization and halogenation reaction conditions to ensure the reaction selectivity and yield.
    Third, there is also a method of starting from simple raw materials and gradually building target molecules through multi-step reactions. Simple and easily modified small molecules are synthesized first, and then pyridine and triazole rings are constructed in sequence through a series of reactions, such as substitution, condensation, cyclization, etc., and iodine atoms are introduced at appropriate stages. This strategy requires comprehensive planning of the reaction sequence, considering the influence of each step on the subsequent reaction check point and functional groups, and carefully optimizing the reaction conditions at each step to make the whole synthesis route efficient and feasible.
    What is the market outlook for 6-Iodo [1,2,4] triazolo [1,5-a] pyridine?
    6-Iodine [1,2,4] triazolo [1,5-a] pyridine, which is of great value in the current market prospect. Guanfu Chemical Chemicals, where new compounds are produced, their prospects are often multi-terminal.
    The first sentence needs one end. In the field of pharmaceutical research and development, many nitrogen-containing heterocyclic compounds are often key raw materials for the creation of new drugs. 6-Iodine [1,2,4] triazolo [1,5-a] pyridine, because of its unique chemical structure, may provide the cornerstone for the construction of new drug molecules, and has potential applications in the development of antibacterial, antiviral and even anti-tumor drugs. If the demand for new drug raw materials in the pharmaceutical industry is increasing, the market demand for this product may also increase.
    Times and the difficulty of synthesis. The difficulty of synthesis is related to the production cost. If the synthesis process is complicated and expensive reagents and harsh reaction conditions are required, the cost may be high when mass production, and the market competitiveness will be weak. However, if a simple and efficient synthesis path can be developed and its cost reduced, it will be possible to expand the scope of market application.
    Furthermore, the situation of similar substitutes is also critical. If there are many alternatives with similar performance and low cost in the market, it is quite difficult for 6-iodine [1,2,4] triazolo [1,5-a] pyridine to gain market share. On the contrary, if its performance is unique and irreplaceable, the market prospect is broad.
    Looking at the general trend of the development of the chemical industry, the concept of green and environmental protection is becoming more and more popular. If the production process of 6-iodine [1,2,4] triazolo [1,5-a] pyridine conforms to the principles of green chemistry, it may be able to conform to the development trend of the industry and win more market opportunities.
    To sum up, the market prospect of 6-iodine [1,2,4] triazolo [1,5-a] pyridine depends on many factors such as pharmaceutical demand, synthesis costs, substitution competition, and environmental compatibility. Although it is difficult to determine its exact trend at present, over time, with the evolution of various factors, its market situation will become clear.