6-(Hydroxymethyl)pyridine-2-carboxamide

6- (hydroxymethyl) pyridine-2-formamide has a wide range of uses. In the field of medicine, this compound is often a key raw material for the creation of new drugs. Due to its unique chemical structure or specific biological activity, it can be used as a target to develop drugs for specific diseases, such as anti-inflammatory and anti-tumor drugs.
In the field of materials science, it also has its uses. Or it can participate in polymer synthesis, giving materials unique properties, such as enhancing material stability and biocompatibility. If it is introduced into polymer materials, it can be used to prepare special materials for biomedical engineering, such as tissue engineering scaffolds and drug sustained-release carriers.
In organic synthetic chemistry, 6- (hydroxymethyl) pyridine-2-formamide is an important intermediate. With its active groups, it can undergo various chemical reactions to derive many organic compounds with complex structures, expanding the synthesis path for organic synthetic chemists, helping to create novel organic molecules, and then promoting the development of organic synthetic chemistry.
In addition, in the field of agricultural chemistry, with appropriate modification or modification, bioactive pesticides and plant growth regulators can be developed. This may provide a new way to improve crop yield and resist pest attacks, which is of great significance to the sustainable development of agriculture.

6- (hydroxymethyl) pyridine-2-formamide is synthesized by different methods. One common method is to use pyridine-2-formamide as the starting material, and introduce hydroxymethyl into the 6-position of the pyridine ring before appropriate reaction conditions. This can be achieved by nucleophilic substitution reaction, such as reacting with pyridine-2-formamide in a suitable hydroxymethyl-containing reagent in an alkaline environment or in the presence of a catalyst.
Another method is to construct the structure of the pyridine ring first, and then add hydroxymethyl at the 6-position. For example, a compound containing carboxyl and amino groups is cyclized to form a pyridine ring, and then the 6-position is modified to introduce hydroxymethyl groups. This cyclization reaction requires attention to the regulation of reaction conditions, such as temperature, pH and reaction time, in order to obtain the desired pyridine ring structure.
Furthermore, starting from other related pyridine derivatives, the functional group can be converted to form hydroxymethyl groups at the 6-position, while retaining the formamide group at the 2-position. In this process, the reagents and reaction conditions need to be carefully selected to ensure the selectivity and yield of the reaction. For example, in some metal-catalyzed reactions, hydroxymethyl groups can be introduced at specific positions of the pyridine ring with precision, and have little effect on other functional groups. In the process of synthesis, attention should be paid to the connection between reaction steps, as well as the purification and identification of the products in each step, in order to achieve the purpose of synthesizing 6- (hydroxymethyl) pyridine-2-formamide.

6- (hydroxymethyl) pyridine-2-formamide is one of the organic compounds. Its physical properties are worth exploring, as follows:
Looking at its properties, under normal circumstances, 6- (hydroxymethyl) pyridine-2-formamide is mostly in the state of white crystalline powder. This morphology is easy to distinguish, and in many chemical operations and applications, powdered materials are more conducive to dispersion, mixing and other operations.
As for the melting point, it has been experimentally determined to be about a specific temperature range. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. This property is of great significance for the purification, identification, and behavior of the compound in high temperature environments. Accurately knowing its melting point can help chemists judge the purity of the substance. If impurities are mixed, the melting point often changes.
Solubility is also one of the important physical properties. 6- (hydroxymethyl) pyridine-2-formamide exhibits different solubility properties in specific solvents. In water, its solubility is moderate, and it can be partially dissolved with moderate stirring, which is due to the interaction of polar groups contained in the molecular structure with water molecules. In organic solvents such as ethanol and dichloromethane, the solubility is better. This solubility characteristic allows chemists to select suitable solvents according to their characteristics in the process of chemical synthesis, separation and purification, so as to achieve the expected chemical reaction or separation effect.
In addition, the density of the compound also has its specific value. Density refers to the mass of the substance per unit volume. This parameter plays a key role in the measurement of the substance, the mixing ratio, and the distribution in different media. Knowing its density can precisely control the dosage of each substance in the reaction system and ensure that the chemical reaction proceeds in the expected direction.
The many physical properties of 6- (hydroxymethyl) pyridine-2-formamide lay the foundation for its research and application in the field of chemistry. Chemists can design experimental schemes according to their physical properties to realize its effective application in synthetic chemistry, medicinal chemistry and many other fields.

6- (hydroxymethyl) pyridine-2-formamide is one of the organic compounds. Its chemical properties are quite unique, so let me tell them one by one.
First of all, its solubility. This substance has a certain solubility in water, and there are hydroxyl groups and amide groups in its molecule. Both are hydrophilic and can form hydrogen bonds with water molecules, so it can be partially dissolved in aqueous solvents. In organic solvents, such as ethanol and acetone, the solubility is also considerable. Due to the principle of similar compatibility, its organic structure is similar to the molecular structure of this type of organic solvent.
Let's talk about its acidity and alkalinity. In the amide group, the lone pair of electrons on the nitrogen atom can be conjugated with the carbonyl group, which reduces the electron cloud density of the nitrogen atom, so its alkalinity is weak. The hydroxyl group can weakly ionize hydrogen ions, making it slightly acidic, but overall, the acidity is also very weak.
In terms of stability, under normal conditions, this compound is quite stable. When encountering strong acids and bases, amide bonds can be hydrolyzed, and hydroxyl groups may also participate in the reaction. If there are appropriate catalysts and conditions, the hydroxymethyl group part can undergo esterification, substitution and other reactions, such as reacting with acyl halides to form ester derivatives; when reacting with halogenated hydrocarbons, substitution can occur to form new carbon-carbon bonds or carbon-heterobond compounds. < Br >
And the pyridine ring in this compound is aromatic, giving it certain stability and special electronic effects. The electron cloud distribution on the pyridine ring is uneven, so that it can participate in a variety of electrophilic substitution and nucleophilic substitution reactions. In the field of organic synthesis, it can be used as a key intermediate and converted into compounds with more complex structures through various reactions.

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First, visit the chemical raw material trading platform. In today's world, the Internet is smooth, and many chemical products are traded on the online platform. On such platforms, you can find the sales information of 6- (hydroxymethyl) pyridine-2-formamide, which is often marked with the price, and the price varies depending on the quantity, quality and supplier.
Second, ask the chemical product supplier. The world's chemical suppliers are like stars, and they specialize in the production and sales of chemical products. You can call, write or go to your company in person to ask about the price of 6- (hydroxymethyl) pyridine-2-formamide. The price quoted by suppliers may vary due to cost considerations and market supply and demand trends.
Third, refer to industry reports and information. In the chemical industry, there are many institutions specializing in information collection and analysis, which often make industry reports, which may involve the market price of 6- (hydroxymethyl) pyridine-2-formamide. Detailed analysis of its price trend, influencing factors, etc., can help people know the approximate range of its price.
I hope I have not seen the exact price range, but in this way, I may be able to get the market price of 6- (hydroxymethyl) pyridine-2-formamide.