6-Hydroxy-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile

6-Hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile, which is an organic compound. Its main use is more common in the field of medicinal chemistry and plays a key role in the process of drug development.
According to the creation of Guanfu Medicine, such compounds are often used as key intermediates. Due to their unique chemical structure, they can be cleverly connected with other molecules through various chemical reactions, thus constructing new compounds with complex structures and specific functions. And these new compounds, or with unique biological activities, can be used as potential drug candidates, bringing hope for the fight against various diseases such as tumors, inflammation, nervous system disorders, etc.
For example, in the exploration of anti-tumor drugs, researchers may use 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile as the starting material, and introduce different active groups through multiple carefully designed synthesis steps, aiming to find new drug molecules with significant inhibitory effects on tumor cell growth and proliferation.
Furthermore, in the field of basic research in pharmaceutical chemistry, this compound is also of important value. Due to its structural characteristics, it can help scientists gain in-depth insight into the interaction mechanism between drugs and biological targets, explore pharmacological processes at the molecular level, and provide a key basis for rational drug design, making drug development more targeted and efficient, reducing blind attempts, and accelerating the pace of new drugs, benefiting the common people.

The synthesis method of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile, although it is not contained in the classic "Tiangong Kaiwu", I can imitate it and express the synthesis idea in ancient Chinese.
To obtain this compound, compounds containing pyridine structure are often used as starting materials. The methoxy group is introduced at a specific position in the pyridine ring first, and this step may require an appropriate alkoxylation reagent and a nucleophilic substitution reaction catalyzed by a base. The type, dosage, reaction temperature and duration of bases need to be carefully regulated to avoid side reactions.
Then when the pyrazole ring is constructed, the reactants undergo a cyclization reaction. Suitable nitrogen-containing reagents and carbonyl compounds can be selected, and in a suitable solvent, under the catalysis of acid or base, condensation and cyclization form pyrazole rings. In this process, the polarity of the solvent and the activity of the catalyst have a great influence on the reaction process.
After the pyrazole and pyridine skeleton is formed, a cyano group is introduced at a specific position. It can be achieved by nucleophilic substitution, nucleophilic addition, etc., such as the reaction of halogenates with cyanide reagents. In this step, attention should be paid to the mild reaction conditions to ensure that the cyano group is introduced accurately.
During the whole synthesis process, the products of each step need to be refined and purified by recrystallization, column chromatography, etc., in order to ensure the purity of the final product and meet expectations. Although the specific method of "Tiangong Kaiwu" is not followed, the idea of synthesis also adheres to the rigor and wisdom of ancient man-made objects, step by step, in order to achieve good results.

6-Hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile, this is an organic compound. Its physical and chemical properties are related to many aspects.
Looking at its appearance, it is often in the state of white to light yellow crystalline powder, delicate and with a specific color, which is the primary characteristic of its visual visibility. Regarding solubility, it has certain solubility in common organic solvents, such as dichloromethane, N, N-dimethylformamide, but it is slightly soluble in water. This difference in solubility is due to the characteristics of functional groups contained in its molecular structure. The interaction between polar functional groups and non-polar parts causes them to show different affinities in different solvents. The melting point of
is also one of the key physical properties. After determination, the melting point is in a specific temperature range, which is of great significance for its identification and purity determination. When heated to the melting point, the substance gradually transitions from solid to liquid state. The accurate determination of this phase transition temperature can help to determine the purity geometry of the compound, and the presence of impurities often causes melting point deviation.
In terms of chemical properties, the hydroxyl group, methoxy group and cyano group in the molecule of this compound are all reactive. Hydroxyl groups can participate in esterification, etherification and other reactions, because the lone pair electrons on the oxygen atom make it easy to interact with electrophilic reagents. Although methoxy groups are relatively stable, they can also participate in substitution reactions under specific conditions. The cyanyl group can be hydrolyzed to generate corresponding carboxylic acids, amides and other derivatives, or participate in nucleophilic addition reactions to expand its chemical transformation path.
Its spectral properties cannot be ignored. In the infrared spectrum, each functional group has a corresponding characteristic absorption peak, such as the stretching vibration peak of the hydroxyl group, the characteristic absorption of the cyanyl group, etc., providing strong evidence for the structure confirmation. In the nuclear magnetic resonance spectrum, hydrogen and carbon atoms in different chemical environments exhibit unique chemical shifts, which help to analyze the molecular structure and the connection mode of each atom.
In summary, the physicochemical properties of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile are rich and diverse, which lays the foundation for its application in organic synthesis, drug development and other fields.

I have not heard of the price of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile in the market. However, if you want to observe the price of this product, you can explore it in various ways.
First, visit the market for chemical materials, ask the shopkeeper, or you can get its price. The price of chemical products in the city varies according to the quality, quantity, and abundance of time. If this product is easy to buy, and there are many people in the market, the price is flat; if it is rare and difficult to produce, and if you are seeking it, the price will be high.
Second, in the "Tiangong Kaiwu", although there is no definite price of this product, it can be referred to in detail on the production and streamer of the product. Looking at other products, if it is difficult to make, the materials used are expensive, and the transportation is inconvenient, the price will be high. 6-Hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile If it belongs to this category, the price is also not cheap.
Third, in this world, the information is smooth and can be sought on the Internet. Websites, forums for chemical materials, or quotations from merchants, or people in the industry say the price of this product. However, the price on the Internet must also be identified as true or false, and cannot be trusted.
In conclusion, if you want to know the market price of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile, you should search for information widely and screen it in detail to get a more accurate price.

The stability of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile depends on whether it can maintain its own structure and properties under different environments. The stability of this substance can be analogous to the ancient golden stone. Under normal circumstances, it seems to be able to stand still. However, under special conditions, it will inevitably change under the ice of fire.
Looking at its chemical structure, specific atomic connections and chemical bonds give it initial stability. The existence of methoxy and hydroxyl groups, or like the barrier of the city, protects the core structure to a certain extent, making it difficult to be easily eroded under common chemical reagents and general temperature conditions, and can maintain its own structural integrity. < Br >
However, the stability is not static. If placed in a state of strong acid and strong alkali, it is like being attacked by a warrior with a sharp weapon. The ions of strong acid and strong alkali are highly active, or can interact with some atoms in the molecule, destroying the original chemical bonds, thereby causing its structure to disintegrate, and its stability is lost.
Temperature is also a key factor. Under high temperatures, molecules gain more energy. If people are full of vitality, atomic movement intensifies. If the temperature is too high, the chemical bonds in the molecule may be unbearable, such as the rope being broken by strong tension, the structure changes, and the stability drops suddenly. However, in a low temperature environment, the molecule seems to fall into a deep sleep, and the atomic movement is soothing, so its stability can be well maintained.
Light can also not be ignored. Light carries energy, such as shadowless arrows, or can stimulate intramolecular electron transitions. Once the electronic state changes, the strength of the chemical bond and the molecular structure may be affected, and the stability may also fluctuate.
Therefore, the stability of 6-hydroxy-4-methoxypyrazolo [1,5-a] pyridine-3-formonitrile is affected by many factors, and it is necessary to carefully consider its environment in order to know the clues of its changes.