6-ethoxypyridine-3-carbaldehyde

6-Ethoxypyridine-3-formaldehyde, this substance has a wide range of uses. In the field of organic synthesis, it is an important raw material and intermediate.
From the perspective of pharmaceutical chemistry, chemists can build many molecular structures with biological activities. Through ingenious reactions, compounds with specific pharmacological effects can be prepared, such as antibacterial, anti-inflammatory, anti-tumor and other drugs, contributing to the conquest of human diseases.
In the field of materials science, it also plays a key role. It can participate in the preparation of organic materials with unique functions, or affect the photoelectric properties of materials, or endow materials with specific adsorption and separation properties. It has potential applications in optoelectronic devices, sensors and other fields.
Furthermore, in the field of fine chemicals, 6-ethoxypyridine-3-formaldehyde can be used to synthesize high-end fragrances, dyes and other fine chemicals. With its unique structure, it endows fragrances with unique aroma characteristics, or brings novel colors and properties to dyes.
In general, 6-ethoxypyridine-3-formaldehyde plays an important role in many chemical-related fields. With its unique chemical structure, it provides diverse possibilities for the development of various fields and promotes the progress of science and technology and industry.

The synthesis method of 6-ethoxypyridine-3-formaldehyde is often studied in the field of organic synthesis. One method can be started by the corresponding pyridine derivative. For example, 6-hydroxypyridine-3-formaldehyde is used as the raw material, and the halogenated ethane is reacted in the presence of a base in a suitable solvent. The base can be selected from potassium carbonate, etc., and the solvent can be selected from N, N-dimethylformamide (DMF). In this reaction process, the halogen atom of halogenated ethane is affected by a base, so that ethoxy negative ions are formed, and then nucleophilic substitution occurs with the hydroxyl group of 6-hydroxypyridine-3-formaldehyde, so 6-ethoxypyridine-3-formaldehyde is obtained.
Another method can be started from the construction of the pyridine ring. With a suitable precursor containing ethoxy and aldehyde, the pyridine ring is constructed by multi-step reaction. For example, with an ethoxy-substituted β-dicarbonyl compound and a nitrogen-containing reagent, under acidic or basic catalysis, the cyclization reaction forms a pyridine ring, and then through appropriate oxidation or functional group conversion, the aldehyde group is introduced, and the final target product is obtained.
In addition, metal-catalyzed coupling reactions can also be used. The coupling of halogenated pyridine derivatives with ethoxyborate in the presence of palladium and other metal catalysts and ligands under suitable reaction conditions, followed by the introduction of aldehyde groups, is an effective strategy for constructing the compound. These methods have their own advantages and disadvantages. In practical application, careful choices should be made according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the purity requirements of the product.

6-Ethoxypyridine-3-formaldehyde is a kind of organic compound. It has unique physical properties and has attracted much attention in the field of chemistry.
Looking at its appearance, it is usually a light yellow to colorless liquid or a crystalline solid under normal conditions. This substance has a specific odor, but its odor properties vary depending on individual olfactory differences, usually with a slight aromatic smell.
The melting point and boiling point of 6-ethoxypyridine-3-formaldehyde are important physical constants. Melting point, the temperature at which a substance changes from solid to liquid state. The melting point of the compound is about 30-40 degrees Celsius, but this value may vary slightly due to the presence of impurities and differences in measurement methods. The boiling point is the temperature at which a substance changes from liquid to gaseous state. At standard atmospheric pressure, the boiling point is about 260-270 degrees Celsius. This higher boiling point indicates strong intermolecular forces, or due to hydrogen bonds, van der Waals forces, etc. The solubility is also a key physical property. 6-ethoxypyridine-3-formaldehyde is soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. In ethanol, because its molecules and ethanol can form hydrogen bonds or have similar polarities, it can be well miscible. However, its solubility in water is relatively low, because the hydrophobic pyridine ring and ethoxy group in the molecule account for a large proportion, resulting in poor hydrophilicity.
In terms of density, the compound has a slightly higher density than water, about 1.1-1.2 g/cm3. This property allows it to be treated according to the difference in density between it and water when it involves operations such as liquid-liquid separation.
In addition, 6-ethoxypyridine-3-formaldehyde has a certain degree of volatility. Although the volatility is not strong, under open environment or heating conditions, the molecular escape rate will be accelerated. This volatility needs to be taken into account when storing and using the compound. It should be stored in a closed container and placed in a cool place to prevent volatilization loss and potential safety risks.

6-Ethoxypyridine-3-formaldehyde is one of the organic compounds. Its chemical properties are quite unique, and the following is described in detail by Jun.
From the perspective of physical properties, this compound is usually in the form of a solid or a liquid, and the specific form varies according to temperature and environmental conditions. It has a specific melting point and boiling point, and the melting point and boiling point values vary depending on purity and test conditions.
In terms of chemical activity, aldehyde groups are the key active sites. The aldehyde groups are active and can participate in many chemical reactions. For example, oxidation reactions can occur, which can be oxidized to carboxyl groups by weak oxidants such as Torun reagent to generate 6-ethoxypyridine-3-carboxylic acids; it can also react with strong oxidants such as potassium permanganate to undergo deep oxidation.
At the same time, aldehyde groups can undergo reduction reactions. Under the action of suitable reducing agents such as sodium borohydride, they can be reduced to alcohols to obtain 6-ethoxypyridine-3-methanol.
Furthermore, aldehyde groups are prone to condensation reactions with compounds containing active hydrogen. For example, they react with amine compounds to form Schiff bases. This reaction is often used in organic synthesis to construct nitrogen-containing heterocycles or new carbon-nitrogen bonds.
The ethoxy group is attached to the pyridine ring, which also affects the properties of the compound. The solitary pair electrons of the oxygen atom in the ethoxy group are conjugated with the pyridine ring, which affects the electron cloud density distribution of the pyridine ring, making the pyridine ring more prone to electrophilic substitution at specific positions. For example, under appropriate conditions, other substituents can be introduced into the pyridine ring to realize structural modification and derivatization.
In addition, the pyridine ring of the compound is also basic and can react with acids to form salts. This property has important applications in separation, purification and certain specific reactions. The chemical properties of 6-ethoxypyridine-3-formaldehyde are rich and diverse, and it has broad application prospects in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate for the synthesis of more complex organic compounds.

I think what you are asking is that 6-ethoxypyridine-3-formaldehyde is in the market price range. However, the price of this product often changes for many reasons, and it is difficult to determine the number.
First, the situation of supply and demand has a great impact. If there are many people in the market, and the supply is small, the price will increase; conversely, if the supply exceeds the demand, the price will drop automatically.
Second, the cost of production is also the key. The price of raw materials, the cost of manufacturing, and the cost of labor are all related to costs. If the price of raw materials rises, or the cost of manufacturing processes is complicated and the cost rises, the price will also increase.
Third, the difference in quality makes the price different. High quality, the price is often higher than ordinary.
Fourth, the price varies from region to region. In different places, the price varies depending on transportation, taxes, market environment, etc.
In terms of common situations, in the chemical raw material market, the price of this product may be between hundreds and thousands of yuan per kilogram. However, this is only a rough range. The actual price must be based on the local market conditions at that time, consult chemical product suppliers, distributors, or refer to the data of relevant trading platforms to obtain a more accurate price.