6 Chloromethyl 2 Cyanopyridine
pyridine pyrrole pyrazine piperidine piperazine

6-Chloromethyl-2-Cyanopyridine

    Specifications

    HS Code

    806618

    Chemical Formula C7H5ClN2
    Molecular Weight 152.58
    Appearance Typically a solid (physical state can vary based on conditions)
    Melting Point Specific value would depend on purity and measurement conditions
    Boiling Point Data would vary based on purity and pressure conditions
    Solubility In Water Limited solubility, as it is an organic compound with polar and non - polar regions
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka No general value available without experimental determination for this compound in specific conditions
    Vapor Pressure Low vapor pressure as it is a relatively high - molecular - weight organic solid
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

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    What is the main use of 6-chloromethyl-2-cyanopyridine?
    The main use of 6-chlorobenzyl-2-chloroanisole is as an intermediate in organic synthesis. It has a wide range of uses in the field of organic synthesis.
    In the synthesis of medicine, it can be used as a key intermediate to produce various drugs through a series of chemical reactions. For example, it can participate in the synthesis process of some antibacterial drugs through specific reaction steps, and its structural characteristics can endow drugs with specific activity and efficacy. Because it contains chlorine atoms and structural parts such as benzyl and anisole, it can cleverly react with other compounds to build the complex molecular structure required for drugs.
    It also plays an important role in the synthesis of pesticides. It can be used to create new types of pesticides, which give pesticides good biological activity and stability due to their chemical properties. For example, pesticides with high-efficiency killing effect on specific pests can be prepared through appropriate reactions. With its unique structure, the targeting of pesticides on pests can be improved, and it is guaranteed to have a certain validity period in the environment without excessive residue, so as to balance the control effect and ecological security.
    In the field of materials science, it is also possible. Or can participate in the synthesis of some functional materials, and give materials specific properties through its structure. For example, by participating in the synthesis of organic materials with special optical and electrical properties, by virtue of their molecular structure, the distribution of electronic clouds within the material is regulated, etc., so that the material exhibits the required optical and electrical characteristics, which contributes to the development of materials science. In short, 6-chlorobenzyl-2-chloroanisole plays a key role in the fields of medicine, pesticides, materials and other fields involved in organic synthesis.
    What are the synthesis methods of 6-chloromethyl-2-cyanopyridine?
    To prepare 6-mercapto-2-mercapto-pyridine, there are many ways to synthesize it. One of the common ones is to use pyridine as the starting material and introduce halogen atoms at a specific position on the pyridine ring through halogenation reaction. In this step, suitable halogenation reagents and reaction conditions need to be selected to ensure that the reaction is controllable and the yield is good. Then, reagents containing thiol groups react with it, and the halogen atoms are replaced by thiol groups to obtain the target product. In this process, the activity of thiol-containing reagents, reaction temperature, time and other factors are all related to the effectiveness of the reaction and need to be carefully regulated.
    There are also those who use the corresponding pyridine derivative as the starting material. First, the derivative is functionally converted to make it have the activity check point for reacting with thiol groups. Then, by interacting with suitable thiolylation reagents, the thiol group is introduced. During this period, it is necessary to consider the influence of the structure of the derivative on the reactivity and selectivity, and carefully select the reaction path and conditions to achieve the purpose of efficient synthesis.
    There are also methods of using transition metal catalysis. Transition metals can activate substrate molecules and promote the binding of thiol groups to pyridine rings. In this method, the type of metal catalyst and the selection of ligands are crucial, which can significantly affect the reaction rate, selectivity and product purity. And the pH, solvent and other factors of the reaction system also need to be properly regulated to create the best reaction environment.
    There are many methods for synthesizing 6-mercapto-2-mercapto-pyridine, and each method has its advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh various factors such as raw material availability, cost, reaction difficulty and product quality, and choose the optimal method to achieve the purpose of synthesis.
    What are the physical properties of 6-chloromethyl-2-cyanopyridine?
    6-Deuterated methyl-2-deuteryl pyridine is a class of compounds in organic chemistry labeled with specific isotopes. Its physical properties are unique, so let me explain them one by one.
    First, its melting point and boiling point. Due to the substitution of deuterium atoms for hydrogen atoms, the intermolecular force changes. The mass of deuterium atoms is greater than that of hydrogen atoms, which makes the molecular movement relatively slow, so its melting point and boiling point are often slightly higher than those of unlabeled similar compounds. This property is of great significance in the separation, purification and phase control of compounds.
    Looking at its density, due to the large mass of deuterium atoms, the density of deuterated methyl-2-deuteryl pyridine is higher than that of ordinary hydrogen-containing congeners. This difference can be used as an important basis for the separation and identification of substances using density differences.
    In terms of solubility, the pyridine ring in its molecular structure has a certain polarity, while the methyl part has a certain non-polarity. The overall solubility is affected by both molecular polarity and deuteration. In common organic solvents such as ethanol and acetone, because they can form appropriate interactions with solvent molecules, they have a certain solubility. However, in water, due to the presence of the overall hydrophobic part of the molecule, the solubility is relatively limited.
    When talking about vapor pressure, due to the change of intermolecular forces, the vapor pressure of deuterated methyl-2-deuteryl pyridine is lower than that of ordinary compounds. This means that at the same temperature, the degree of volatilization is relatively small. In the process of chemical production and storage, vapor pressure properties are related to the volatility and stability of substances, and are crucial for setting operating conditions and selecting storage environments.
    Furthermore, its spectral properties are also changed by deuterium generation. In the infrared spectrum, the vibration frequency of the carbon-deuterium bond is significantly different from that of the carbon-hydrogen bond, and a unique absorption peak appears, which can be used for the structural identification and quantitative analysis of compounds. In the nuclear magnetic resonance spectrum, the magnetic properties of the deuterium atom are obviously different from the hydrogen atom, generating a specific signal, which provides a powerful means for the study of molecular structure and kinetics.
    What are the precautions for storing and transporting 6-chloromethyl-2-cyanopyridine?
    6-Chlorobenzyl-2-naphthyl ether, there are many things to pay attention to during storage and transportation.
    Its nature may be more active, and it may be dangerous in case of heat, open flame, oxidant, etc. Therefore, when storing, it must be placed in a cool and ventilated warehouse, away from fire and heat sources, and should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed with storage. In the warehouse, suitable materials should be prepared to contain leaks.
    During transportation, do not slack off. Make sure that the container is well sealed to prevent it from leaking, collapsing, falling, and damaging. When transporting, the selected vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. The planning of driving routes should avoid residential areas and densely populated areas. During summer transportation, special attention should be paid to preventing sun exposure, driving speed should not be too fast, and sudden braking should be avoided.
    During loading and unloading, caution is also required. Operators should be specially trained and strictly abide by the operating procedures. When loading and unloading, they should be lightly loaded and unloaded to prevent damage to packaging and containers. If a leak occurs accidentally, the personnel from the contaminated area of the leak should be quickly evacuated to the safe area and quarantined to strictly restrict access. Emergency personnel must wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and do not directly contact the leak. Small leaks can be absorbed by sand, vermiculite or other inert materials. If there is a large amount of leakage, it is necessary to build a dike or dig a pit to contain it, transfer it to a tanker or a special collector with a pump, and recycle it or transport it to a waste treatment site for disposal.
    In this way, 6-chlorobenzyl-2-naphthyl ether can be safely stored and transported.
    What is the market prospect of 6-chloromethyl-2-cyanopyridine?
    Wen Jun inquired about the market prospect of 6-hydroxyethyl-2-hydroxypropyl ether. This substance has a wide range of uses and has its presence in various fields of chemical industry.
    In the paint industry, it can be a solvent and a film-forming auxiliary. In today's paint market, environmental protection is on the rise, and water-based coatings are gradually becoming the mainstream. 6-hydroxyethyl-2-hydroxypropyl ether in water-based coatings can improve the leveling and gloss of coatings, and help reduce surface tension, make the coating more uniform, and reduce the drawbacks such as orange peel and shrinkage. With the increasing demand for environmentally friendly coatings in construction, furniture and other industries, its usage in the paint field is expected to increase.
    In the field of ink, its role cannot be underestimated. It can improve the solubility and dispersion of ink, making the ink color more vivid and the printing effect better. Coupled with the continuous development of the packaging and printing industry, the demand for high-quality inks continues to grow, and this ether substance also has a broad space in the ink market.
    Furthermore, in the adhesive industry, it can enhance the stickiness and flexibility of the adhesive. With the improvement of adhesive performance requirements in electronics, automotive and other industries, 6-hydroxyethyl-2-hydroxypropyl ether, with its unique properties, may become a key ingredient in the optimization of adhesive formulations, thus driving the growth of market demand.
    However, although the market prospect is good, there are still challenges. The chemical industry is fiercely competitive, and similar alternative products may pose a threat to its market share. And the fluctuation of raw material prices will also affect production costs and market prices. However, overall, with the development of various application industries, the market prospect of 6-hydroxyethyl-2-hydroxypropyl ether is promising, and it is expected to further expand in the future market.