6-chloro-H-imidazo[1,2-a]pyridine

6-Chloro-H-imidazolo [1,2-a] pyridine, this is an organic compound. It has a wide range of uses and has important applications in many fields.
In the field of medicinal chemistry, this compound plays a key role. Many drug research and development use it as the core starting material or key intermediate. Due to its unique chemical structure, it can participate in a variety of chemical reactions. After ingenious design and synthesis, it can be converted into drug molecules with specific pharmacological activities. For example, in the synthesis of some drugs used to treat neurological diseases, 6-chloro-H-imidazolo [1,2-a] pyridine is an indispensable component, or participates in the construction of the active core structure of the drug, or affects the binding mode of the drug and the target, which in turn affects the efficacy and selectivity of the drug.
In the field of materials science, this compound also shows potential value. Due to its specific electronic structure and chemical properties, it can be used to prepare functional materials. Such as the research and development of some photoelectric materials, 6-chloro-H-imidazolo [1,2-a] pyridine can be appropriately modified and polymerized to regulate the electrical and optical properties of the materials, and is expected to be applied to organic Light Emitting Diode (OLED), solar cells and other fields, providing new ideas and approaches for the design and preparation of new materials.
In agricultural chemistry, 6-chloro-H-imidazolo [1,2-a] pyridine can be used as an important intermediate for the synthesis of pesticides. By reacting with other chemicals, pesticide products with insecticidal, bactericidal or weeding effects can be prepared. Its unique structure helps to improve the effect of pesticides on specific targets, while reducing the impact on the environment and non-target organisms, providing assistance for the development of high-efficiency, low-toxicity, and environmentally friendly pesticides.

6-Chloro-H-imidazolo [1,2-a] pyridine, this is an organic compound. Its physical properties are related to many aspects, let me go through them one by one.
When it comes to appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. The appearance is delicate, like the first snow in winter, pure and with a specific form. This form is quite influential in many chemical reactions and industrial applications.
In terms of melting point, it is about 120-125 ° C. The characteristics of the melting point are like the unique "temperature label" of a substance. When the temperature gradually rises, 6-chloro-H-imidazolo [1,2-a] pyridine slowly melts from the solid state to the liquid state. This process is like melting ice and snow, and the morphology changes. The accurate determination of the melting point is of great significance in the identification of the purity of the substance and the control of related processes.
The boiling point is usually above 300 ° C. The boiling point characterizes the temperature required for the compound to transform from liquid to gaseous state. The high boiling point indicates that the intermolecular force is strong and can be converted into a gaseous state under high temperature environments. This property is a key consideration in chemical operations such as distillation and separation.
Solubility is also an important physical property. 6-Chloro-H-imidazolo [1,2-a] pyridine is slightly soluble in water, like a hermit in water, and is difficult to blend with water. However, it is soluble in common organic solvents such as ethanol and dichloromethane. In solvents such as ethanol, it is like a duck to water and evenly dispersed. This solubility lays the foundation for its application in organic synthesis, drug development and other fields.
Density above, although no exact value is widely circulated, based on its molecular structure and the characteristics of similar compounds, the density should be slightly higher than that of water. This density characteristic affects the distribution and behavior of substances in the process of mixing and separation.
The physical properties of 6-chloro-H-imidazolo [1,2-a] pyridine are as important as cornerstones in many fields such as chemical research, industrial production, and drug creation, providing a key basis for related operations and applications.

The chemical synthesis of 6-chloro-H-imidazolo [1,2-a] pyridine is an important topic in the field of organic synthesis. There are various synthesis paths, each with its own advantages and disadvantages, and it should be selected according to specific needs and conditions.
Common synthesis methods, one is to start with pyridine derivatives and halogenated acetonitrile. Shilling pyridine derivatives react with halogenated acetonitrile under the catalysis of bases to form key intermediates. This step requires careful temperature control and reaction time, and the type and dosage of bases also have a significant impact. Commonly used bases such as potassium carbonate, sodium carbonate, etc., may be at room temperature to tens of degrees Celsius. The intermediate is obtained, and then the cyclization reaction is carried out to construct the skeleton of imidazolo [1,2-a] pyridine. During cyclization, specific catalysts, such as metal salts, may be required to promote the efficient reaction.
Second, nitrogen-containing heterocycles and chlorinated reagents are used as raw materials. First prepare suitable nitrogen-containing heterocycles, and then introduce chlorine atoms with chlorinated reagents. The choice of chlorinated reagents is quite important, such as dichlorosulfoxide, phosphorus oxychloride, etc., whose activities and reaction conditions are different. During operation, attention should be paid to the anhydrous environment of the reaction system to avoid hydrolysis of chlorinated reagents and reduce the reaction yield. During the reaction process, it is also necessary to monitor the reaction process, and adjust the reaction conditions in a timely manner by means of thin layer chromatography.
There is also a method of synthesis by multi-step series reaction. The several-step reaction is connected in series and carried out continuously in the same reaction system to reduce the separation and purification steps of intermediates and improve the synthesis efficiency. However, this method requires extremely high control of the reaction conditions, and the reaction conditions of each step need to be compatible in order to achieve the desired goal.
In short, the synthesis of 6-chloro-H-imidazolo [1,2-a] pyridine requires comprehensive consideration of many factors such as raw material availability, cost, reaction conditions and yield, and a carefully designed synthesis route to achieve the purpose of efficient and economical synthesis.

It is difficult to determine the price range of 6-chloro-H-imidazolo [1,2-a] pyridine in the market. The price often changes due to many factors, such as quality, purity, purchase quantity, supply and demand, and the market conditions are also changing rapidly.
Looking at past transactions, the price may vary due to differences in purity. If the purity is quite good, almost high-purity products, the price per gram may reach tens of gold or even hundreds of gold. However, if the purity is slightly lower, it is the degree commonly used in industry, and the price may be reduced to a few gold to tens of gold per gram.
The purchase quantity is also a major factor. If the buyer's demand is very large, in terms of kilograms or even tons, the merchant may give a discount to promote the sale, and the price may be several gold per gram lower than the retail price.
The situation of supply and demand also affects the price. When the market demand for this product is strong and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price may drop.
In addition, the price varies in different places. In prosperous ports, with convenient transportation and prosperous business, the price may be relatively easy; while in remote places, the price may be slightly higher due to transportation and logistics costs. Therefore, in order to know the exact price of 6-chloro-H-imidazolo [1,2-a] pyridine, we should carefully consider various factors and consult various suppliers to observe the current market situation.

6-Chloro-H-imidazolo [1,2-a] pyridine, the preparation of this substance is quite professional, and it is occasionally involved in various chemical and pharmaceutical fields. In this case, its manufacturer is located in the land of China, and many factories specializing in chemical synthesis may operate.
In the past, in the land of Jiangnan, there was a factory name called Ruixiang Chemical, which was known for fine chemical synthesis, and had deep attainments in the preparation of nitrogen-containing heterocyclic compounds. Products such as 6-chloro-H-imidazolo [1,2-a] pyridine may be produced by its workshop.
In the land of Yanzhao in the north, Hongtai Chemical is also a chemical giant. Its scientific research teacher, who specializes in chemical technology, also dabbles in the synthesis of heterocyclic compounds, or has produced this product for the needs of various chemical pharmaceuticals.
In addition, on the coast of the East China Sea, on the Pearl Shanghai, there is a scientific innovation enterprise, called Xingchen Bio, focusing on the creation of biomedical raw materials, with its cutting-edge technology, or also for the production of 6-chloro-H-imidazolo [1,2-a] pyridine, adding to the building blocks.
However, the chemical industry is not a single company. Within the four seas, there may be many specialized small factories hidden in the city, which also manage this industry. Although their reputation is not obvious, they are skilled and are a solid part of the chemical chain. They silently help the production of 6-chloro-H-imidazolo [1,2-a] pyridine for the needs of the world's chemical and pharmaceutical industries.