6 Chloro 4 Ethylamino 3 Pyridinecarboxaldehyde
pyridine pyrrole pyrazine piperidine piperazine

6-chloro-4-(ethylamino)-3-Pyridinecarboxaldehyde

    Specifications

    HS Code

    399222

    Chemical Formula C8H9ClN2O
    Molecular Weight 184.62
    Physical State At Room Temperature Solid (assumed based on similar compounds)
    Solubility In Water Low solubility expected (due to non - polar groups)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    What are the chemical properties of 6-chloro-4- (ethylamino) -3-Pyridinecarboxaldehyde?
    6-Chloro-4- (ethylamino) -3-pyridyl formaldehyde, this is an organic compound. Looking at its structure, the chlorine atom is attached to the 6 position of the pyridine ring, the 4 position is connected with ethylamino group, and the 3 position is aldehyde group.
    Its chemical properties, the first is the characteristics of aldehyde groups. The aldehyde group has high reactivity and can undergo many reactions. If it is oxidized, it can be oxidized to carboxyl groups in case of mild oxidizing agents, such as Toran reagent, to obtain corresponding pyridyl carboxylic acid derivatives; in case of strong oxidizing agents, such as potassium permanganate, it can also be oxidized, and the pyridine ring may be affected to cause structural changes. A reduction reaction can occur, and the aldehyde group can be reduced to a hydroxyl group to obtain 6-chloro-4- (ethylamino) -3-pyridyl methanol.
    Furthermore, ethylamino also participates in the reaction. Amino groups are basic and can form salts with acids and bind to protons. Because their nitrogen atoms have lone pairs of electrons, they can participate in nucleophilic substitution reactions as nucleophiles. Pyridine rings are aromatic and can undergo electrophilic substitution reactions, but due to the existence of chlorine, aldehyde groups and ethylamino groups, the reactivity and check point are affected. Chlorine atoms are electron-withdrawing groups, which reduce the electron cloud density of the pyridine ring, slightly reduce the activity of electrophilic substitution reaction, and the localization effect makes the new substituents enter the specific position of the pyridine ring.
    This compound is rich in chemical properties and can be used as a key intermediate in the field of organic synthesis to construct complex pyridine compounds, providing a basis for research in pharmaceutical chemistry, materials science and other fields.
    What are the synthesis methods of 6-chloro-4- (ethylamino) -3-Pyridinecarboxaldehyde
    To prepare 6-chloro-4- (ethylamino) -3-pyridine formaldehyde, the method is as follows:
    First take the appropriate pyridine compound as the starting material. For example, under specific reaction conditions, a pyridine derivative is introduced into the chlorine atom at position 6. This process requires the selection of suitable chlorination reagents, such as chlorine-containing halogenating agents, and the reaction in a suitable solvent and temperature environment. The chlorination agent and the pyridine derivative are fully interacted, and through a series of reaction steps, the intermediate product of 6-chloropyridine derivatives can be reached.
    Then, the ethylamino group is connected at position 4. In this step, ethylamine or its derivatives can be selected. With the help of a suitable catalyst, under certain temperature and pressure conditions, through the reaction mechanism such as nucleophilic substitution, the ethylamino group is introduced to obtain 6-chloro-4- (ethylamino) pyridine derivatives.
    Finally, the resulting derivative is subjected to aldehyde-ylation reaction. Specific oxidation or other aldehyde-ylation methods can often be used. For example, with a suitable oxidizing agent, under precise control of the reaction conditions, the pyridine ring at the No. 3 position can be converted into an aldehyde group. During the reaction, attention should be paid to the reaction process and product purity, or the impurities should be removed through separation and purification to finally obtain 6-chloro-4- (ethylamino) -3-pyridine formaldehyde. Each step of the reaction requires precise control of factors such as temperature, reagent dosage, and reaction time in order to make the reaction efficient and the product pure.
    What is the main use of 6-chloro-4- (ethylamino) -3-Pyridinecarboxaldehyde?
    6-Chloro-4- (ethylamino) -3-pyridine formaldehyde is one of the organic compounds. This compound has important uses in many fields.
    In the field of medicinal chemistry, it is often the key intermediate for the synthesis of drugs. Using it as the starting material, through a series of chemical reactions, a drug molecular structure with specific biological activities can be constructed. Due to the unique properties of functional groups such as pyridine ring, chlorine atom and aldehyde group in the structure, it can endow the synthesized drugs with various biological activities, such as antibacterial, anti-inflammatory and anti-tumor effects. The presence of the coine-pyridine ring helps to enhance the interaction between drugs and biological targets; chlorine atoms can enhance the lipid solubility of drugs, thereby improving the pharmacokinetic properties of drugs; aldehyde groups can participate in a variety of chemical reactions, providing many possibilities for the modification of drug structures.
    In the field of materials science, 6-chloro-4- (ethylamino) -3-pyridyl formaldehyde is also used. Or it can be used to prepare functional materials, such as fluorescent materials. Its structural properties or make it exhibit fluorescence properties under specific conditions, which can be used in the preparation of fluorescent probes for biological imaging, environmental monitoring and other fields. With its selective recognition and fluorescence response to specific substances, sensitive detection of target substances can be achieved.
    In addition, in organic synthesis chemistry, this compound, as an important intermediate, can participate in many organic reactions, such as nucleophilic addition reactions, condensation reactions, etc., laying the foundation for the construction of more complex organic molecular structures. By ingeniously designing reaction routes and leveraging the activity of functional groups contained in them, chemists can synthesize organic compounds with novel structures and unique properties, promoting the development of organic synthesis chemistry.
    What is the market outlook for 6-chloro-4- (ethylamino) -3-Pyridinecarboxaldehyde?
    Today, there are 6-chloro-4- (ethylamino) -3-pyridyl formaldehyde. This compound is in the market prospect, and the answer is based on the ancient classical text of "Tiangong Kaiwu".
    Looking at the world, all kinds of things have their own uses, and they all depend on people's needs. This 6-chloro-4- (ethylamino) -3-pyridyl formaldehyde, although not widely known, has its own unique needs in various fields.
    In the field of medicine, this aldehyde compound may be used as a raw material for medicine. Doctors often need to study various medicines in order to treat people's diseases. And this compound, or because of its unique structure, can play a key role in the synthesis of drugs. At present, everyone hopes that the drug is powerful and harmless, so the demand for drug research and development is increasing. If this compound can help the improvement of medicine, it must have the need and good prospects in the pharmaceutical market.
    In the chemical industry, the chemical industry is related to the formation of many utensils. This compound may be a raw material for a certain type of fine chemicals, helping it to generate unique properties. The development of chemical industry is changing with each passing day, and the demand for various special raw materials is also increasing. If its performance is unique, it can make chemical products have better properties, such as durability, beauty, etc., the chemical industry may have more to buy, and the market prospect can also be viewed.
    However, looking at the state of the market, the situation is changing. Although this compound is available, it also needs to look at the difficulty and cost of its preparation. If the preparation is difficult and the cost is high, it will be difficult to be widely used in the market despite the demand. And the competition of peers cannot be ignored. If there are other things that can be used instead and have more advantages, the road to the market may be bumpy.
    In summary, 6-chloro-4- (ethylamino) -3-pyridyl formaldehyde may have opportunities in the fields of medicine and chemical industry, but the market prospect still depends on the preparation, cost, competition and many other things.
    What are the storage conditions for 6-chloro-4- (ethylamino) -3-Pyridinecarboxaldehyde?
    6-Chloro-4- (ethylamino) -3-pyridyl formaldehyde is one of the organic compounds. Its storage conditions are crucial and related to the quality and stability of this substance.
    Cover this substance should be placed in a cool, dry and well-ventilated place. A cool person can avoid the harm of high temperature. High temperature can greatly increase the activity of molecules, or initiate chemical reactions, causing them to deteriorate. If the temperature is too high, it may accelerate its volatilization, reduce its content, or change its internal structure and lose its original characteristics. Therefore, it should be controlled at a suitable low temperature, generally speaking, 2-8 ° C. This temperature range can keep its chemical properties stable and prevent it from changing due to heat.
    Dry environment is indispensable. Water vapor in the air, or interact with the compound. If the environment is humid, water vapor adsorbs on its surface, or penetrates into the interior, or causes reactions such as hydrolysis to occur. The change of hydrolysis can break its molecular structure, change its chemical composition, and lose its function. It is necessary to avoid moisture. It can be stored and disposed of as a desiccant to absorb water vapor and keep it dry.
    Good ventilation is also essential. If the ventilation is poor, the volatile gas of the compound gathers in one place, or reaches a dangerous concentration, in case of open flames and other incentives, it may cause explosions and other disasters. And ventilation can dissipate harmful gases generated by chemical reactions, ensuring the safety of the storage environment.
    In addition, when storing this substance, it should be stored separately from oxidants, acids, bases, etc. These substances are chemically active and meet 6-chloro-4- (ethylamino) -3-pyridyl formaldehyde, which is easy to react chemically. Oxidants can cause oxidation, and acids, bases or structural changes can damage their quality.
    It needs to be stored in a sealed container. Sealing can prevent the intrusion of external air, water vapor and impurities, keep it pure, and maintain its chemical stability. During storage, it should also be checked regularly to see if it has any signs of deterioration, such as changes in color and smell. If there is any abnormality, take measures to prevent it from further deterioration.