6-Chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid

6-Chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid, its chemical structure is formed by fusing the pyridine ring with the pyrrole ring. The pyridine ring is a six-membered nitrogen-containing heterocyclic ring, which is aromatic, and the nitrogen atom occupies a specific position in the ring. The pyrrole ring is a five-membered nitrogen-containing heterocyclic ring, which is also aromatic and fused with the pyridine ring in a specific way. Specifically, some carbon atoms of the pyrrole ring are shared with some carbon atoms of the pyridine ring, forming a pyrrolido [3,2-c] pyridine ring fused ring system.
In this fused ring system, the 6th position is replaced by a chlorine atom, that is, the chlorine atom is directly connected to the pyrrolido [3,2-c] pyridine ring. In the 2nd position, there is a carboxyl group, which is composed of a carbonyl group connected to a hydroxyl group, and is connected to the 2nd carbon atom of the pyrrolido [3,2-c] pyridine ring through chemical bonds.
This chemical structure imparts specific physical and chemical properties to the 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid. Due to the aromaticity of the ring system, it has certain stability and conjugation effect; the presence of chlorine atoms affects molecular polarity and reactivity; the acidic properties of carboxyl groups enable the compound to participate in many acid-base reactions and other related chemical reactions, and may have important uses in organic synthesis, medicinal chemistry, and other fields.

The common synthesis method of 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid is based on the technology of chemical synthesis. One method is to take the appropriate pyridine derivative as the starting material, and introduce the chlorine atom at a specific position through the halogenation reaction. This halogenation reaction often requires careful selection of halogenating reagents and reaction conditions to achieve the purpose of precise positioning.
Then, through ingenious construction of pyrrole ring structure, this step often relies on specific organic synthesis reactions, such as condensation reaction, cyclization reaction, etc. In this process, the temperature, time, and proportion of reactants of the reaction need to be carefully regulated to obtain the prototype of the target compound. < Br >
Another method can start from a compound containing a pyrrolido-pyridine skeleton and introduce a carboxyl group at a specific position through a carboxylation reaction. There are various means of carboxylation, or carboxylation reagents can be used under suitable catalysts and reaction environments to make the reaction proceed smoothly.
Furthermore, a multi-step tandem reaction strategy can be adopted. The starting material is gradually converted into functional groups. By ingeniously designing the reaction path, each step of the reaction is linked to each other, so as to efficiently synthesize the target product. However, these methods require a deep understanding of the reaction mechanism and strict control of the experimental conditions in actual operation in order to improve the yield and purity of the product and achieve the purpose of synthesis.

6-Chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid, which has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate. It can be converted into biologically active compounds through specific chemical reactions and used in the development of new drugs. Its unique structure allows it to interact with specific targets in organisms, or it can be a potential active ingredient in the treatment of diseases.
In the field of materials science, it can be used to prepare functional materials. Due to its specific chemical structure, it endows materials with unique properties, such as optical, electrical or thermal properties, so it can be used in optical materials, electronic devices and other fields.
In the field of organic synthesis, it is an important building block. Chemists use various reactions to connect them with other organic molecules to build complex organic structures and expand the types and functions of organic compounds.
In short, 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acids are of great value in many scientific fields. With further research, its potential uses are expected to be further expanded and explored.

6-Chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid, this is an organic compound. Its physicochemical properties are particularly important for its application in many fields.
In terms of its appearance, it often takes the form of a white to off-white solid powder, which is conducive to its dispersion and participation in various reaction systems. Looking at its solubility, it shows good solubility in common organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), but its solubility in water is relatively limited. This solubility property is of great significance in the field of drug research and development, because the good solubility in organic solvents helps the synthesis, separation and purification of drug molecules, and moderate water insolubility can affect the release and metabolism of drugs in the body.
Its melting point is also one of the key physical properties. After determination, the melting point of the compound is in a specific temperature range. This temperature characteristic can not only be used to identify the substance, but also in its preparation and processing process, it is of great significance for the precise control of temperature. If the temperature is not properly controlled, it may cause the crystal transformation of the compound, which in turn affects its chemical stability and biological activity.
When it comes to chemical properties, the presence of chlorine atoms and pyridine and pyrrole rings in this compound gives it unique reactivity. Chlorine atoms have certain nucleophilic substitution activities, which can react with many nucleophilic reagents, thereby introducing different functional groups, expanding the structural diversity of compounds, and can be used as an important intermediate in the field of organic synthesis for constructing more complex organic molecular structures. At the same time, the conjugation system of pyridine ring and pyrrole ring makes it have certain electron delocalization characteristics, which affects the electron cloud distribution of molecules, and then affects its chemical reaction selectivity. Its carboxyl functional group is typically acidic, which can neutralize with bases to generate corresponding carboxylic salts. This property may have important applications in the process of drug salt formation, improving the solubility and stability of drugs through salt formation.

6-Chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid, an organic compound, is widely used in the fields of medicinal chemistry and organic synthesis. However, its market price range is difficult to determine due to many factors.
First, the production scale has a great impact on the price. If the manufacturer has large-scale capacity, the unit production cost may be reduced by the scale effect, and the product price may be close to the people. On the contrary, when small-scale production, the cost is high and the price will rise.
Second, the cost of raw materials is also the key. The preparation of 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid requires specific raw materials, and the price of raw materials fluctuates, which is directly related to the price of finished products. If raw materials are scarce or production costs are high, the price of 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid will be affected and rise.
Third, the market demand and competition situation should not be underestimated. The market demand for this compound is strong, but the supply is limited, and the price will rise; conversely, if the market competition is fierce, manufacturers may reduce prices in order to compete for share.
According to past market transactions and related information, the price per gram of 6-chloro-1H-pyrrolido [3,2-c] pyridine-2-carboxylic acid may range from tens to hundreds of yuan. However, this is only a rough range. The actual price changes rapidly with market conditions. When purchasing, consult the supplier in detail to obtain an accurate quotation.