6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid

6-Chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, this is an organic compound. Its chemical structure is quite unique.
Look at its structure, a fused ring system containing pyrrolido-pyridine. Pyrrolido-pyridine is formed by the ingenious fusing of pyrrole rings and pyridine rings, and the two share two adjacent carbon atoms. This fused ring structure gives the compound specific chemical and physical properties. In the pyrrolido-pyridine system, 1H indicates that there is a hydrogen atom at position 1 of the pyrrole ring.
Furthermore, when chlorine atoms are introduced at the 6th position, the chlorine atoms have strong electronegativity, which will have a significant impact on the electron cloud distribution and chemical reaction activity of the molecule. It can reduce the density of electron clouds in adjacent and para-positions, resulting in electrophilic substitution reactions that are more likely to occur in the meta-position; at the same time, the presence of chlorine atoms also affects the physical properties of molecules such as polarity and fat solubility.
And the carboxyl group (-COOH) at the 3rd position brings acidity to the compound. Carboxyl groups can undergo many chemical reactions, such as salt formation reactions and esterification reactions. In organic synthesis, carboxyl groups often participate in various reactions as key functional groups to construct more complex compounds.
The chemical structure of 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid integrates many key structural elements such as fused ring, halogen atom and carboxyl group, which makes it show potential application value in organic synthesis, medicinal chemistry and other fields.

6-Chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is an organic compound. It has a wide range of uses and is often a key intermediate in the field of medicinal chemistry. Due to its unique chemical structure, it can participate in a variety of chemical reactions and help synthesize various biologically active compounds.
Looking at the field of drug development, with its structural characteristics, it can be chemically modified and modified to derive many potential therapeutic drugs. For example, it may be used to prepare inhibitors targeting specific disease targets, which are expected to have therapeutic effects on certain diseases.
In the field of materials science, it may also have potential applications. Due to its special chemical properties, it may participate in the construction of new organic materials and give new properties to materials. Such as the development of materials with special optical and electrical properties to meet different technical needs.
Furthermore, in organic synthetic chemistry, 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is often used as a starting material or key intermediate. Through various reaction pathways, complex organic molecular structures are constructed, providing an important cornerstone for the development of organic synthetic chemistry and expanding the boundaries and possibilities of synthetic chemistry.

The synthesis of 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is a key field of organic synthetic chemistry. To synthesize this compound, the common way is to use suitable pyridine derivatives as starting materials. First, specific modifications are made to the pyridine ring, and suitable substituents are introduced to lay the foundation for the subsequent construction of the pyrrole ring.
Nucleophilic substitution reaction can be used to introduce chlorine atoms at specific positions in the pyridine ring. This step requires careful selection of reaction conditions and reagents to ensure accurate positioning of chlorine atoms. Subsequently, the pyrrole ring structure is established through cyclization reaction. This process may require the help of a specific catalyst and a suitable reaction medium to efficiently promote cyclization. For example, Lewis acid catalysts can be used to create a chemical environment conducive to the formation of pyrrole rings.
In addition, there are also those who use nitrogen-containing heterocyclic compounds as starting materials. Through multi-step reactions, the overall structure of the target molecule is gradually constructed. During this time, many reaction types such as oxidation, reduction, and condensation are involved. For example, the initial heterocyclic ring is oxidized first, and its electron cloud distribution is adjusted so that subsequent reactions are more likely to occur. After condensation reaction, the various parts are cleverly connected to obtain the target 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid.
Or it can be synthesized from a simple organic small molecule through a multi-step series reaction. This strategy requires delicate design of the reaction sequence and conditions, so that each step of the reaction is closely connected, and the synthesis efficiency and yield are improved. There are many paths for synthesis. It is necessary to carefully weigh and choose the best one according to factors such as the availability of raw materials, the controllability of reaction conditions, and cost-effectiveness.

6-Chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is an organic compound with specific physical properties. Its appearance is mostly white to off-white solid powder, which is easy to store and transport, and is easy to use and measure in many chemical reactions.
The melting point of this compound is in a specific range, generally between 240-245 ° C. As an important physical property, the melting point is of great significance to the purity and structural stability of the compound. This melting point range indicates that the intermolecular force of 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is stable, and a higher temperature is required to break the lattice structure and cause its melting.
Its solubility is also a key physical property. In common organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it exhibits good solubility and can form a homogeneous solution, which is conducive to participating in various reactions as reactants or intermediates in organic synthesis and drug development. However, its solubility in water is poor, because its molecular structure contains hydrophobic pyridine and pyrrole rings, which reduce the chance of forming hydrogen bonds with water molecules.
In addition, the density of 6-chloro-1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid is about 1.6 g/cm ³. Density, as an intrinsic property of the substance, has important guiding value in determining the dosage and space occupied by the compound in the material preparation and process design.
In terms of spectral properties, its infrared spectrum will show a characteristic absorption peak at a specific wave number. For example, carboxyl (-COOH) groups have strong absorption peaks at 1700-1725 cm. This indicates the stretching vibration of carbonyl (C = O). The C-H bond between pyridine and pyrrole rings has stretching vibration absorption peaks at 3000-3100 cm. These spectral characteristics can be used for structural identification and purity analysis of the compound.

I have not heard of the price of "6-chloro-1H-pyrrolo [2,3-b] pyridine-3-carboxylic acid" in the market. This is a fine chemical substance, and its price often varies depending on the purity of the quality, the situation of demand and supply, and the complexity and simplicity of the system. If the quality is pure and high, the supply is small, and the system is difficult, the price will be high; conversely, the quality is coarse, the supply is small, and the system is easy, and the price is low.
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