6-carbomethoxy-2-oxa-1,2-dihydropyridine-3-carboxylic acid

6-Methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid. Looking at its name, it can be seen that this is one of the organic compounds. From its naming analysis, "6-methoxycarbonyl" means that at the 6th position of the pyridine ring, there is a substituent such as methoxycarbonyl (-COOCH). This substituent is formed by connecting carbonyl (C = O) with methoxy (-OCH). Carbonyl is electrophilic, and methoxy has an impact on the distribution of electron clouds.
"2-oxane" indicates that the carbon atom at position 2 of the pyridine ring is replaced by an oxygen atom. The pyridine ring is originally a nitrogen-containing hexamembered heterocycle, and the replacement of this oxygen atom greatly changes the electron cloud density and chemical properties of the ring. Compared with the ordinary pyridine ring, the electron cloud on the ring is more biased towards the oxygen atom due to the higher electronegativity of the oxygen atom than that of the carbon, which changes the reactivity at other positions on the ring.
"1,2-dihydropyridine" indicates that the position 1 and 2 in the pyridine ring is a single bond state after double bond hydrogenation. This structural change changes the conjugate system of the original pyridine ring, and the stability and reactivity also change accordingly. Compared with the aromatic conjugation system of pyridine, the degree of conjugation of dihydropyridine is reduced, the energy state is changed, and it shows different properties in chemical reactions.
"3-carboxylic acid", that is, there is a carboxyl group (-COOH) attached to the third position of the pyridine ring. The carboxyl group is acidic and can undergo acid-base reactions, and the synergistic effect of its carbonyl group and hydroxyl group allows this compound to participate in many esterification, amidation and other reactions.
Overall, the chemical structure of 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid shows unique chemical properties due to the interaction of these substituents with the ring structure. In the field of organic synthesis, it can be used as a key intermediate to participate in the construction of various complex organic compounds.

6-Methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Gein dihydropyridine compounds often have unique biological activities. With 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid as the starting material, chemically modified and reacted, drug molecules with specific pharmacological activities can be constructed, or used in the creation of drugs for the treatment of cardiovascular diseases. By regulating ion channels and other mechanisms, the normal function of the cardiovascular system can be maintained. < Br >
In the field of organic synthesis, as an important building block, it can participate in diverse reactions. For example, condensation and addition reactions occur with compounds containing active hydrogen or unsaturated bonds to build more complex organic molecules, expand the structural diversity of organic compounds, and provide powerful tools for organic synthesis chemists to explore new compounds and new reaction pathways.
In materials science-related research, through appropriate chemical transformation, it may be introduced into the structure of polymer materials to endow materials with special properties. Such as improving the stability and optical properties of materials, it provides the possibility for the research and development of new functional materials. In conclusion, 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid has important potential value in many fields, which is of great significance for promoting the development of related science and technology.

The method for preparing 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid is not detailed in the ancient book "Tiangong Kaiwu", but it can be deduced from the ancient chemical preparation principles and modern organic synthesis methods.
First look at the structure of this compound, which contains functional groups such as methoxycarbonyl, dihydropyridine ring and carboxylic acid. The preparation method can start from the construction of the pyridine ring.
First, a suitable β-ketoate can be reacted with ammonia or amine compounds. Beta-ketoate is condensed with ammonia and cyclized to form a pyridine ring structure. For example, methyl acetoacetate is reacted with ammonia under suitable catalyst and temperature conditions. The catalyst can be selected from Lewis acid, such as ZnCl ², in a suitable solvent, such as ethanol or toluene, heated and refluxed, which can promote its cyclization to form pyridine derivatives. Then the resulting product may need to be further modified to obtain a specific substituent of the target compound.
Second, a multi-step reaction strategy is used. Intermediates containing part of the target structure can be prepared first, and then functional groups can be converted to obtain the target. For example, a compound with a pyridine ring skeleton and convertible functional groups is first synthesized, and then its specific position functional groups are converted into methoxycarbonyl and carboxylic acids through esterification, oxidation and other reactions. For example, halogenated pyridine derivatives are used as starters, methoxycarbonyl is introduced through metal-catalyzed carbonylation, and then specific groups are oxidized to carboxylic acids under suitable conditions.
During the reaction process, attention should be paid to the precise control of the reaction conditions. Temperature, reaction time, and the proportion of reactants all have a significant impact on the reaction yield and product purity. If the temperature is too high, or side reactions occur, the product is complex and difficult to separate; improper proportion of reactants also affects the reaction process and yield.
Separation and purification are also key steps. After the reaction, it can be purified by distillation, recrystallization, column chromatography, etc. according to the physical and chemical properties of the product and the impurity. If the boiling point difference between the product and the impurity is large, distillation can be used; if the solubility of the product in a solvent changes significantly with temperature, recrystallization can be effectively purified; column chromatography is suitable for separating mixtures with similar structures. In this way, after various steps, 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid can be obtained.

6-Methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid has various physical and chemical properties. Its shape or white to off-white crystalline powder is solid at room temperature and has good stability. However, in strong acid and alkali environments, it may cause chemical reactions and cause structural changes.
When it comes to solubility, it is slightly soluble in common organic solvents such as ethanol and acetone, but partially soluble; in water, its solubility is poor and insoluble. This property is related to the molecular structure. The polar groups in the molecule interact with the non-polar part, resulting in its solubility. < Br >
Its melting point is also an important physical property. After measurement, it is about a specific temperature range. This melting point can be used as the basis for identification and purity judgment. When heated, it melts into a liquid state. If it continues to heat up or triggers a decomposition reaction, the molecular structure is destroyed and other substances are formed.
In terms of chemical properties, due to the presence of active groups such as methoxycarbonyl and carboxyl groups, it can participate in a variety of chemical reactions. Carboxyl groups are acidic and can neutralize with bases to form corresponding salts; methoxycarbonyl groups can be hydrolyzed, and under the catalysis of acids or bases, carboxyl groups and methanol are formed. In addition, the compound may participate in esterification, amidation and other reactions, and has great application potential in the field of organic synthesis.

What you are inquiring about is the price range of 6-methoxycarbonyl-2-oxa-1,2-dihydropyridine-3-carboxylic acid in the market. However, the price of this product varies due to many reasons, and it is difficult to determine its fixed number.
First, the supply and demand situation in the market is the main factor for the change in price. If there are many people who want it, and there are few people who supply it, the price will increase; if the supply exceeds the demand, the price may drop. Second, the place where this product is produced also affects its price. Different origins, due to different raw materials, methods and freight, the price also varies. Third, the quality of the quality also affects the price. < Br >
As far as I know, if I want to know the price of this product, I can consult various merchants in the chemical raw material market in detail, or check it on the network of chemical transactions to get a near real-time price. Although it is difficult to determine the range of its price, it may be possible to know its approximate price through this route.