6 Bromopyridine 2 Carbohydrazide
pyridine pyrrole pyrazine piperidine piperazine

6-bromopyridine-2-carbohydrazide

    Specifications

    HS Code

    343044

    Name 6-bromopyridine-2-carbohydrazide
    Chemical Formula C6H6BrN3O
    Molar Mass 216.036 g/mol
    Appearance Solid (predicted)
    Solubility In Water Low solubility (organic compound with polar and non - polar parts)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, DMSO
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    Frequently Asked Questions

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    What are the chemical properties of 6-bromopyridine-2-carbohydrazide?
    6-Bromopyridine-2-formylhydrazide is a member of the family of organic compounds. This substance contains bromine atoms and formylhydrazide groups, and has specific chemical properties due to its unique structure.
    First talk about its physical properties. At room temperature, it may be white to pale yellow crystalline powder with a certain melting point and boiling point. It shows a certain solubility in organic solvents such as ethanol and dichloromethane, but its solubility in water may be limited.
    Besides chemical properties, its formylhydrazide group is active and can participate in many chemical reactions. It is easy to condensate with aldodes and ketones to form hydrazone compounds. This reaction is of great significance in the field of organic synthesis and is often a key step in the construction of nitrogen-containing heterocyclic compounds. Due to its structure containing nitrogen atoms, it can be used as a ligand to complex with metal ions to form metal complexes, which has potential application value in catalysis, materials science and other fields.
    In addition, the presence of bromine atoms introduces unique reactivity to the compound. Bromine atoms can undergo nucleophilic substitution reactions and are replaced by other nucleophilic reagents such as alcohols and amines. By means of this, the structure of the compound is modified to synthesize a series of derivatives, and its applications in pharmaceutical chemistry, materials science and other fields are expanded.
    Its pyridine ring imparts aromatic and basic properties to the molecule. The nitrogen atom on the pyridine ring has a lone pair electron, so that the compound can bind to protons, exhibit a certain alkalinity, and can participate in acid-base related chemical reactions.
    The chemical properties of 6-bromopyridine-2-formylhydrazide have attracted much attention in many fields such as organic synthesis, drug development, materials science, etc., and have become an important organic intermediate in chemical research and industrial production.
    What are the common synthetic methods of 6-bromopyridine-2-carbohydrazide?
    6-Bromopyridine-2-formyl hydrazide is also an organic compound. The common method of synthesis is to use 6-bromopyridine-2-formic acid as the starting material. First, it is heated with thionyl chloride, and this step aims to convert the carboxyl group into an acid chloride. 6-bromopyridine-2-formic acid and thionyl chloride are heated to a certain temperature in a suitable reaction vessel and maintained for several hours, and the acid chloride is formed.
    Then, the resulting acid chloride is reacted with hydrazine hydrate. In an appropriate solvent, such as anhydrous ethanol, hydrazine hydrate is slowly added, and the two are nucleophilic substitution reaction to obtain 6-bromopyridine-2-formylhydrazide. This reaction requires attention to the ratio of the reaction temperature to the material. If the temperature is too high or too low, the proportion of the material is improper, which can affect the yield and purity of the product.
    There are also those who use 6-bromopyridine-2-formate as a raw material. First, 6-bromopyridine-2-formate ethyl ester is treated with ethanol and sodium hydroxide solution, and hydrolysis is carried out to change the ester group to a carboxyl group. Then, according to the above method of using 6-bromopyridine-2-formic acid as raw material, acid chloride is first prepared, and then reacted with hydrazine hydrate to obtain 6-bromopyridine-2-formylhydrazide. In this way, the hydrolysis step needs to control the reaction conditions to ensure complete hydrolysis and avoid adverse effects on the pyridine ring and bromine atoms. During synthesis, each step needs to be carefully operated and monitored to obtain pure 6-bromopyridine-2-formylhydrazide.
    In what areas is 6-bromopyridine-2-carbohydrazide applied?
    6-Bromopyridine-2-formylhydrazide has applications in various fields such as medicine and materials.
    In the field of medicine, it has great potential. It can be used as an intermediate for drug synthesis, and it can be combined with other compounds through specific chemical reactions to construct a biologically active molecular structure. For example, it may be able to participate in the construction of drugs targeting specific disease targets, and is expected to be applied to the development of anti-tumor, anti-infection and other drugs. Due to its unique chemical structure, it can interact with specific proteins, enzymes, etc. in organisms to interfere with disease-related physiological processes and achieve therapeutic purposes.
    In the field of materials, it also has its uses. Or it can be used to prepare functional materials, such as fluorescent materials. The structure of 6-bromopyridine-2-formylhydrazide can be appropriately modified and assembled to endow the material with unique optical properties, which can play a role in optical sensing and display. When a specific substance or environment changes, the fluorescence properties of the material may be changed, thereby realizing the detection of the target substance.
    In addition, in the field of organic synthetic chemistry, it is an important synthetic building block. Chemists can carry out various reactions based on this to construct complex organic molecules, expand the types and structures of organic compounds, and promote the development of organic synthetic chemistry. For example, by reacting with aldose, ketone and other compounds, new nitrogen-containing heterocyclic structures are formed, enriching organic synthesis strategies and product types.
    What is the market price of 6-bromopyridine-2-carbohydrazide?
    6-Bromopyridine-2-formylhydrazide, the price of this product in the market often varies due to many reasons. First, the difficulty of preparation is involved. If the preparation method is complicated, special raw materials, exquisite skills and cumbersome processes are required, the cost will be high, and the price in the market will also be high. Second, the state of supply and demand determines the price. If there is a large number of people in the market, but the supply is small, and the supply is in short supply, the price will rise; conversely, if the supply exceeds the demand, the price may drop. Third, the price of raw materials is also the key. The price of the raw materials required for preparation fluctuates, and the price of 6-bromopyridine-2-formylhydrazide also fluctuates. In addition, the price set by different manufacturers will also vary due to their own cost considerations and market strategies.
    Looking at the market in the past, the price of 6-bromopyridine-2-formylhydrazide has changed every time. At some times, due to the improvement of the preparation process, the cost has to drop, and the price has also been reduced. However, sometimes, due to the scarcity of raw materials and the surge in demand, the price has risen. If you want to obtain an accurate market price, it is advisable to check the chemical product trading platform and consult the industry merchants in order to obtain the current exact price.
    What are 6-bromopyridine-2-carbohydrazide storage conditions?
    6-Bromopyridine-2-formyl hydrazide is one of the chemical substances. Its storage conditions are quite important, which is related to the stability and quality of this substance.
    This substance should be stored in a cool, dry and well-ventilated place. Cover a cool place to reduce the risk of decomposition and deterioration due to excessive temperature. High temperature often promotes chemical reactions to accelerate, or causes material structure changes and loses its original characteristics. Dry environment is also indispensable, because moisture is easy to cause adverse reactions such as hydrolysis. Water can interact with many chemical substances, destroy its chemical structure, reduce its purity and damage its effectiveness. Good ventilation can disperse volatile substances that may accumulate in time, avoid safety hazards caused by its high concentration, and prevent it from adversely reacting with other substances in the environment.
    In addition, keep away from fire and heat sources when storing. Both fire and heat sources can cause a sudden rise in temperature, trigger violent chemical reactions, or even cause serious accidents such as combustion and explosion. At the same time, they should be stored separately from oxidants, acids, and bases, and must not be mixed. Because oxidants have strong oxidizing properties, they can react with 6-bromopyridine-2-formylhydrazide for oxidation and reduction; acids and bases can damage their chemical properties due to acid and alkali properties, or neutralization reactions with them.
    In addition, storage containers should also be carefully selected. It is advisable to use well-sealed containers to prevent them from coming into contact with outside air, moisture, etc. Suitable material containers can avoid reactions with substances and maintain their purity and stability. In summary, following these storage conditions, 6-bromopyridine-2-formylhydrazide should be properly stored to maintain its good quality and chemical properties.