6 Bromoimidazo 1 2 A Pyridine 3 Carbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde

    Specifications

    HS Code

    995468

    Chemical Formula C9H7BrN2O
    Molecular Weight 239.07
    Appearance Typically a solid (description may vary)
    Melting Point Data may vary depending on purity
    Boiling Point Unspecified, but relevant to its vaporization conditions
    Solubility Solubility characteristics can vary with solvents like organic solvents
    Density Data specific to the compound needs determination
    Pka Relevant for its acidic - basic behavior in solution (data may vary)
    Flash Point Important for fire - hazard assessment (data required)
    Refractive Index Useful for identification and purity determination (data may vary)

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    General Information
    Where to Buy 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde in China?
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    Frequently Asked Questions

    As a leading 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 6-Bromoimidazo [1,2-a] pyridine-3-carbaldehyde
    6 - Bromoimidazo [1,2 - a] pyridine - 3 - carbalaldehyde is an organic compound with unique chemical properties. Its appearance may be solid, and the specific color may vary depending on the purity and preparation method.
    In this compound, the presence of bromine atoms, imidazolopyridine rings and aldehyde groups endows it with various chemical activities. The aldehyde groups are typically reactive and can participate in many organic reactions, such as oxidation reactions, which can be oxidized by mild oxidants to corresponding carboxylic acids; in reduction reactions, they can be reduced to alcohols. In addition, aldehyde groups can also undergo condensation reactions with amino-containing compounds to form imines. The bromine atom is also a key activity check point, which can be replaced by other nucleophiles through nucleophilic substitution reactions to achieve structural modification of compounds, thus expanding its application in the field of organic synthesis. The imidazolopyridine ring endows molecules with certain aromaticity and stability, which affects the physical and chemical properties of compounds. Its nitrogen atom can be used as an electron donor to participate in coordination chemistry related reactions and form complexes with metal ions, which may have potential uses in the fields of materials science and catalysis.
    Due to its special chemical properties, 6 - Bromoimidazo [1,2 - a] pyridine - 3 - carbalaldehyde has attracted much attention in the fields of medicinal chemistry and materials science, providing an important structural basis for the development of new drugs and the creation of functional materials.
    What are the synthesis methods of 6-Bromoimidazo [1,2-a] pyridine-3-carbaldehyde
    The synthesis method of 6-bromimidazolo [1,2-a] pyridine-3-formaldehyde is not included in the classic "Tiangong Kaiwu", but the current organic synthesis method is often followed by numerical methods.
    First, imidazolo [1,2-a] pyridine is used as a base, and bromine atoms are introduced at the 6th position by halogenation reaction, and then the aldehyde group is added at the 3rd position by formylation reaction. During halogenation, a brominating agent such as N-bromosuccinimide (NBS) can be selected, and in a suitable solvent such as dichloromethane, under the action of an initiator such as benzoyl peroxide, light or heat can be used to make the bromine atoms fall precisely at the 6th position. The Vilsmeier-Haack reaction is the best for formylation. N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl) are used to prepare an active formylation reagent, which is co-heated with 6-bromo imidazolo [1,2-a] pyridine, and the aldehyde group is formed at the 3rd position.
    Second, it can be prepared from pyridine derivatives by multi-step cyclization, halogenation, formylation and other reactions. First, pyridine derivatives and suitable bifunctional reagents are cyclized to form imidazolo [1,2-a] pyridine structures under alkali catalysis, and then halogenated and formylated according to the previous method. < Br >
    Third, there are also methods of transition metal catalysis. For example, palladium catalysis is used to make the substrate containing bromine and pyridine structure and the aldehyde-containing precursor directly form the target molecule through coupling reaction. This requires careful selection of ligands, bases and reaction solvents to achieve efficient and highly selective synthesis.
    Synthesis methods have their own advantages and disadvantages, and need to be selected according to many factors such as the availability of raw materials, the ease of control of reaction conditions, and the purity of the product.
    6-Bromoimidazo [1,2-a] What is the main use of pyridine-3-carbaldehyde?
    6 - Bromoimidazo [1,2 - a] pyridine - 3 - carbalaldehyde, Chinese name 6 - bromoimidazo [1,2 - a] pyridine - 3 - formaldehyde, this substance is widely used. In the field of medicinal chemistry, it is often a key intermediate for the creation of many bioactive compounds. Due to its unique chemical structure, it can interact with specific targets in organisms and help develop specific drugs such as antibacterial, antiviral, and anti-tumor.
    It also plays an important role in the field of organic synthetic chemistry. With its own functional group characteristics, it can participate in a variety of organic reactions, such as nucleophilic substitution, redox, condensation reactions, etc., providing the possibility to construct complex organic molecular structures, and then synthesize new materials, dyes or fragrances.
    In the field of materials science, specific compounds synthesized from this substance as a starting material may have unique electrical, optical, and thermal properties, which can be applied to cutting-edge fields such as electronic devices and optical materials. For example, in the development of organic Light Emitting Diode (OLED) materials, rational molecular design and modification may improve the luminous efficiency and stability of materials.
    In summary, 6-Bromoimidazo [1,2-a] pyridine-3-carbalaldehyde has important uses in many scientific fields and has made significant contributions to the development of related fields.
    What is the market price of 6-Bromoimidazo [1,2-a] pyridine-3-carbaldehyde
    What I am asking you is about the market price of 6 - Bromoimidazo [1,2 - a] pyridine - 3 - carbalaldehyde. Sadly, this product is not included in "Tiangong Kaiwu", because the technology of chemical synthesis at that time was not as developed as it is today, and such fine organic compounds have not yet been invented.
    However, today is different from the past. To know the market price of this product, it is necessary to consider many factors. First, the difficulty of its production process. If the synthesis steps are complicated, the reaction conditions are demanding, and the raw materials are scarce, the cost will be high, and the price will be expensive. Second, the market supply and demand situation. If the demand is strong and the supply is limited, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. Third, the purity of the product. High purity is mostly used in high-precision fields such as pharmaceutical research and development, and the price is much higher than that of ordinary purity.
    In the current market, the price of this product fluctuates frequently. To get an accurate price, you can consult the chemical product trading platform, or contact the professional chemical raw material supplier. The price may vary depending on the amount of purchase, and when purchasing in bulk, there may be a preferential price. Therefore, the exact price is difficult to sum up in a word, and it depends on the actual market situation.
    6-Bromoimidazo [1,2-a] What are the precautions in storage and transportation of pyridine-3-carbaldehyde
    6-Bromimidazolo [1,2-a] pyridine-3-formaldehyde is an important organic compound, and many matters need to be paid attention to during storage and transportation.
    First word storage. This compound is quite sensitive to environmental factors, so it needs to be placed in a dry place. Humid gas can easily lead to chemical reactions and cause it to deteriorate. I still remember that in the past, a workshop caused the same compound to be damp due to uncontrolled humidity in the storage place, and eventually lost its effectiveness. Furthermore, temperature is also critical. Store in a cool place to avoid hot topics. High temperature can easily promote its decomposition, or cause dangerous reactions. For example, in the past, there were cases of high temperature causing compounds to decompose and smoke. In addition, it must be stored separately from oxidizing agents, acids, alkalis, etc. Contact with these substances can easily cause chemical reactions, or even cause serious consequences such as explosions.
    As for transportation, it should not be ignored. The packaging must be tight to prevent leakage. In the past, there have been accidents where the packaging was damaged during transportation and the compound leaked and caused environmental pollution. During transportation, the vehicle should keep running smoothly to avoid bumps and vibrations. Vibration or damage to the packaging, and may stimulate internal reactions of the compound. At the same time, the transportation personnel must be professionally trained and familiar with the characteristics of this compound and emergency treatment methods. If there is an unexpected situation during transportation, it can be properly disposed of in time. In conclusion, the storage and transportation of 6-bromimidazolo [1,2-a] pyridine-3-formaldehyde is related to safety and quality, and all aspects need to be treated with caution and operated according to regulations to ensure safety.